Discover and read the best of Twitter Threads about #stemcell
Most recents (13)
🔥Crohn’s Perianal Fistula - #MondayNightIBD w all🌟faculty 🔥 CME 👉 bit.ly/CPF2 🔸Supported by an edu grant from @TakedaPharma 🔸 twitter.com/i/broadcasts/1…
2/#MondayNightIBD #Crohns #PerianalFistula #MedTwitter #GITwitter
✅Answer #IBDPolls👇
🗓 Mark your calendar - Live Q&A @ 8p ET/5p PT
📲Tweet your❓to be addressed Monday!
📸 Faculty disclosures & important CME info👇
✅Answer #IBDPolls👇
🗓 Mark your calendar - Live Q&A @ 8p ET/5p PT
📲Tweet your❓to be addressed Monday!
📸 Faculty disclosures & important CME info👇
3/#MondayNightIBD #GITwitter #MedTwitter
#Crohns #PerianalFistula #CPF
@BonumCe
👇Answer Pre-Polls before watching 👇
#Crohns #PerianalFistula #CPF
@BonumCe
👇Answer Pre-Polls before watching 👇
📣#GITwitter
Join⚕️@DCharabaty @AmyLightnerMD #DrMarlaDubinsky+ Brandon Pomish 4 #Crohns #PerianalFistula
🗓️#CPF #MNIBDWebinar Sat 2/11
🎯MultiD Mgmt
🎯Stem Cell Therapy
🎯#PatientExperience
🆓#CME👉bit.ly/CPF-MNIBD-CME
🗳️#IBDPolls👇
🔸Supported by an edu grant @TakedaPharma
Join⚕️@DCharabaty @AmyLightnerMD #DrMarlaDubinsky+ Brandon Pomish 4 #Crohns #PerianalFistula
🗓️#CPF #MNIBDWebinar Sat 2/11
🎯MultiD Mgmt
🎯Stem Cell Therapy
🎯#PatientExperience
🆓#CME👉bit.ly/CPF-MNIBD-CME
🗳️#IBDPolls👇
🔸Supported by an edu grant @TakedaPharma
1/#PreConvo #IBDPoll #Crohns #PerianalFistula
#MNIBDWebinar #CPF
🆓#CME🔗bit.ly/CPF-MNIBD-CME
🟢Where are you in your career?
#MNIBDWebinar #CPF
🆓#CME🔗bit.ly/CPF-MNIBD-CME
🟢Where are you in your career?
2/#PreConvo #IBDPoll 1️⃣
#MNIBDWebinar #Crohns #PerianalFistula #CPF
🆓#CME🔗bit.ly/CPF-MNIBD-Pre2
🟢The addition of which of the following to an anti-TNF agent is associated with a higher rate of #Crohns #PerianalFistula CPF healing vs the anti-TNF agent alone?
#MNIBDWebinar #Crohns #PerianalFistula #CPF
🆓#CME🔗bit.ly/CPF-MNIBD-Pre2
🟢The addition of which of the following to an anti-TNF agent is associated with a higher rate of #Crohns #PerianalFistula CPF healing vs the anti-TNF agent alone?
Bench to bedside series: Lung COPD part 1/3
Respiratory histology (via @drawittoknowit)
Health & COPD Lung @TheLancet
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Respiratory histology (via @drawittoknowit)
Health & COPD Lung @TheLancet
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Bench to bedside series: Lung COPD part 2/3
2. #Pathophysiology of #COPD via @EricWong_MD
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
2. #Pathophysiology of #COPD via @EricWong_MD
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Bench to bedside series: Lung COPD part 3/3
#scRNAseq paper: Human distal airways contain a multipotent secretory cell that can regenerate alveoli
1. RASCs (new cell-type) + #stemcell properties in distal airways 2. faulty RASC-to-AT2 transformation in COPD
#Bioinformatics #MedEd
#scRNAseq paper: Human distal airways contain a multipotent secretory cell that can regenerate alveoli
1. RASCs (new cell-type) + #stemcell properties in distal airways 2. faulty RASC-to-AT2 transformation in COPD
#Bioinformatics #MedEd
Healthy Lung vs. Lung with Chronic Obstructive Pulmonary Disease (COPD)
h/t @PatologCritica
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #lung #COPD #INNOMed
h/t @PatologCritica
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #lung #COPD #INNOMed
Bench to bedside series: Lung COPD part 1/3
Respiratory histology (via @drawittoknowit)
Health & COPD Lung @TheLancet
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Respiratory histology (via @drawittoknowit)
Health & COPD Lung @TheLancet
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Bench to bedside series: Lung COPD part 2/3
2. #Pathophysiology of #COPD via @EricWong_MD
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
2. #Pathophysiology of #COPD via @EricWong_MD
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
1/ Incredibile ma è successo. È appena uscito su @ScienceAdvances il paper a cui ho lavorato tutta l'estate in collaborazione con il lab di Friburgo!
Tutto è cominciato da questo meraviglioso set up... ma di cosa tratta questa ricerca? Vediamolo assieme!
science.org/doi/full/10.11…
Tutto è cominciato da questo meraviglioso set up... ma di cosa tratta questa ricerca? Vediamolo assieme!
science.org/doi/full/10.11…
2/ Le cellule staminali sono un modello perfetto per ottenere cellule cardiache che battono spontaneamente e continuamente nel dish del laboratorio.
Quelle che vedete nel video sono proprio loro. Cellule atriali cardiache ottenute da staminali pluripotenti indotte. #18Novembre
Quelle che vedete nel video sono proprio loro. Cellule atriali cardiache ottenute da staminali pluripotenti indotte. #18Novembre
3/ Recentemente è stato scoperto un canale (una proteina) chiamato WiChR che proviene dalla specie marina Wobblia Lunata.
Questo canale è estremamente sensibile alla luce blu e, in presenza di quest'ultima, si attiva provocando una corrente di potassio... dove voglio arrivare?
Questo canale è estremamente sensibile alla luce blu e, in presenza di quest'ultima, si attiva provocando una corrente di potassio... dove voglio arrivare?
1/ Out now on @ScienceAdvances!
#StemCells are a wonderful tool to create atrial cardiomyocytes that spontaneously and continuosly beat in a dish… but what happens if we transfect them with the highly potassium selective channelrhodopsin WiChR? #Thread
science.org/doi/full/10.11…
#StemCells are a wonderful tool to create atrial cardiomyocytes that spontaneously and continuosly beat in a dish… but what happens if we transfect them with the highly potassium selective channelrhodopsin WiChR? #Thread
science.org/doi/full/10.11…
2/ WiChR is a channel that comes from the marine species Wobblia Lunata.
Differently from previosly described K+-conducting channels such as HcKcR1, this channel is characterized by small photocurrent inactivation and improved light sensitivity. #Thread #Physiology #Optogenetics
Differently from previosly described K+-conducting channels such as HcKcR1, this channel is characterized by small photocurrent inactivation and improved light sensitivity. #Thread #Physiology #Optogenetics
There’s been some questions recently here about the types of #IBD research that @CrohnsColitisFn supports. I want to highlight some of the innovative projects that we are working on to bring us closer to our vision of a future free from #CrohnsDisease & #UlcerativeColitis.
.@CrohnsColitisFn is proud to be a collaborator on over 200 #IBD research projects in the US & around the world that are helping to improve patient quality of life and bring us closer to cures. Here are some examples:
We support the work of researchers at @ut_dallas who developed and are testing a wrist-watch like device that monitors sweat for biomarkers that could indicate an #IBD flare: crohnscolitisfoundation.org/blog/researche…
Bench to bed series: Lung COPD part 1/3
1. #Respiratory #histology (via @drawittoknowit)
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
1. #Respiratory #histology (via @drawittoknowit)
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Bench to bed series: Lung COPD part 2/3
2. #Pathophysiology of #COPD via @EricWong_MD
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
2. #Pathophysiology of #COPD via @EricWong_MD
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Bench to bed series: Lung COPD part 3/3
#scRNAseq paper: Human distal airways contain a multipotent secretory cell that can regenerate alveoli
1. RASCs (new cell-type) + #stemcell properties in distal airways 2. faulty RASC-to-AT2 transformation in COPD
#Bioinformatics #meded
#scRNAseq paper: Human distal airways contain a multipotent secretory cell that can regenerate alveoli
1. RASCs (new cell-type) + #stemcell properties in distal airways 2. faulty RASC-to-AT2 transformation in COPD
#Bioinformatics #meded
Quite remarkable results in this
5 year-old suffering severe post-effects of
a rare form of autoimmune 🧠encephalitis
journals.sagepub.com/doi/10.1177/09… #snrtg #medtwitter #openscience #scicomm #neurology #immunology #stemcell
5 year-old suffering severe post-effects of
a rare form of autoimmune 🧠encephalitis
journals.sagepub.com/doi/10.1177/09… #snrtg #medtwitter #openscience #scicomm #neurology #immunology #stemcell
"The patient was in a vegetative state when she was first admitted to hospital and received cell therapy as a last resort."
...she is now ready to attend school.
...she is now ready to attend school.
These results need to be replicated in additional patients, however initial results look extremely compelling.
main.icmr.nic.in/sites/default/…
Important @ICMR statement on evidence based use of #StemCell Therapy based on critical review of literature & claims by large panel of academic clinicians, which I had the privilege to lead. #StemCells often hyped & shouldn't be offered as #StandardOfCare
Important @ICMR statement on evidence based use of #StemCell Therapy based on critical review of literature & claims by large panel of academic clinicians, which I had the privilege to lead. #StemCells often hyped & shouldn't be offered as #StandardOfCare
Inherent public appeal of #StemCellTherapy is being exploited & promoted unethically as a #MagicRemedy to vulnerable patients & should be regulated. There are many diseases where Basic/Translational/Clinical Research can establish its utility @ISSCR @ICMR @fda @ema leads the way!
Acutely aware that patients & their groups want freedom to try whatever might help them & detest when the academic medical community or regulators are so hung up on #RiskBenefitRatio & good evidence and till then say this therapy they cannot take outside regulated clinical trials
Our first paper authors.elsevier.com/a/1cRqD6tu0Cbo… is now out @CellStemCell! With @ionispharma & the Jamieson Lab @UCSanDiegoDRM, we found that selective #antisense oligonucleotides inhibiting #IRF4 reduce disease burden & #multiplemyeloma #regeneration in #cancer models. @CellPressNews 1/
IRF4 (interferon regulatory factor 4) is a key plasma cell transcription factor that is known to play a critical role in #myeloma progression. It's been shown to activate networks of #cellcycle and cancer regulators, including the notorious #cancer and #stemcell gene, #MYC. 2/
In this new work, the talented @PhoebeMondala & @AshniVora first dug deeper into the IRF4 networks activated in high-risk forms of #myeloma, including #plasmacellleukemia. IRF4 target genes (SLAMF7, BCMA) were widely induced, especially among genes regulating the #cellcycle. 3/
"You don't see radio changing gradually and suddenly become radar. #Darwin's theory doesn't work for #technology, and we have to make a new observation."
- W Brian Arthur at SFI today
#evolution #innovation #invention
- W Brian Arthur at SFI today
#evolution #innovation #invention
"Novel technologies are constructed from existing technologies. These offer themselves as components for the construction of further technologies."
- W Brian Arthur at SFI today
#evolution #innovation #invention #technology #engineering #design
- W Brian Arthur at SFI today
#evolution #innovation #invention #technology #engineering #design
Unlike the two-parent #inheritance typical to (but not ubiquitous among) #complex organisms, #technology inherits features from n parents - a "vast ancestral #network" more like horizontal gene transfer networks in #bacteria.
W Brian Arthur on sumulating #invention on a chip:
W Brian Arthur on sumulating #invention on a chip:
Thread:
As #AspenIdeaHealth concludes today I will share with you some of my reflections. It was a pleasure to see @jrovner @EricTopol @davidrosenthal @olgakhazan @WalterIsaacson Aviv Regev of @MIT and others.
As #AspenIdeaHealth concludes today I will share with you some of my reflections. It was a pleasure to see @jrovner @EricTopol @davidrosenthal @olgakhazan @WalterIsaacson Aviv Regev of @MIT and others.
It is truly humbling and awe-inspiring to realize that our human body is made up of a congealing of pulsating energy and elements of the stardust that began its life with the primordial big bang.
The body has ~37 trillion cells that all began with a single event of the union of Shiva and Shakti and the creative energy expansion that followed. Here is Aviv Regev on cells:
