Discover and read the best of Twitter Threads about #MTX
Most recents (5)
#Methotrexate is the nr1⃣drug of choice for Rheumatoid #Arthritis.
MTX's history is eventful, and deserves a 🧵
🔹It started with childhood leukeamia
🔹Sleeping Beauty in the 1960-70's
🔹Awakened by Hoffmeister
🔹FDA👍1988 and 🔝 in the 1990's
1/🧵 #RheumTwitter #MedTwitter
MTX's history is eventful, and deserves a 🧵
🔹It started with childhood leukeamia
🔹Sleeping Beauty in the 1960-70's
🔹Awakened by Hoffmeister
🔹FDA👍1988 and 🔝 in the 1990's
1/🧵 #RheumTwitter #MedTwitter
The start:
🔹1948, Dr Farber treated 5 children with #leukemia with Aminopterin, an anti-folate & precursor of #MTX, with outstanding results
🔹1951, first positive results of Aminopterin in #RA & #Psoriasis pts
Despite this, Aminopterin was aborted in RA
2/🧵 #RheumTwitter
🔹1948, Dr Farber treated 5 children with #leukemia with Aminopterin, an anti-folate & precursor of #MTX, with outstanding results
🔹1951, first positive results of Aminopterin in #RA & #Psoriasis pts
Despite this, Aminopterin was aborted in RA
2/🧵 #RheumTwitter
MTX enters:
Due to difficulties in manufacturing, Aminopterin was modified and MTX was created.
🔹1962, positive results with MTX in both RA and #PSA
🔹Next 10 years: MTX was extensively studied in #psoriasis but halted in #RA
🔹In RA, MTX becomes the Sleeping Beauty👸💤
3/🧵
Due to difficulties in manufacturing, Aminopterin was modified and MTX was created.
🔹1962, positive results with MTX in both RA and #PSA
🔹Next 10 years: MTX was extensively studied in #psoriasis but halted in #RA
🔹In RA, MTX becomes the Sleeping Beauty👸💤
3/🧵
Methotrexate is an important part of lupus care. We are aware of reports that some people are having difficulty accessing methotrexate in the wake of the Supreme Court’s ruling in the Dobbs case. 
The health of all people with lupus is of utmost importance to the Lupus Foundation of America. We are working with our Medical-Scientific Advisory Council to guide our efforts going forward so we can help ensure that people with lupus have access to the treatments they need.
If you are a person with #lupus experiencing challenges accessing #methotrexate (#MTX), please email access@lupus.org with details of your experience.
The ACR is aware of the emerging concerns surrounding access to needed treatments such as #MTX after the recent decision in Dobbs v. Jackson Women’s Health Organization.
We are following this issue closely to determine if #rheum providers & patients are experiencing any widespread difficulty accessing #MTX
or if any initial disruptions are potentially temporary & due to the independent actions of pharmacists trying to figure out what is & isn’t allowed where they practice.
@MondayNightIBD @southasianIBD @ibdesis @Empoweringpts9 @DCharabaty @ownyourcrohns @crohnsbabble @LivingWithUmeed @vkckiranpullela @TheMaveilousGut @dunung_ruchita 📣 #IBD patients & caregivers:
#IBDPoll 1️⃣
📊Thinking abt your IBD needs, what's been the biggest hurdle to your care?
📝 In the replies, elaborate. What’s helped your care?
Please share your #PatientExperience w #MondayNightIBD 👇🏽
👨👩👧👦=Family
👩🏼🤝👩🏽=Friends
🥼=Specialist
#IBDPoll 1️⃣
📊Thinking abt your IBD needs, what's been the biggest hurdle to your care?
📝 In the replies, elaborate. What’s helped your care?
Please share your #PatientExperience w #MondayNightIBD 👇🏽
👨👩👧👦=Family
👩🏼🤝👩🏽=Friends
🥼=Specialist
@MondayNightIBD @southasianIBD @ibdesis @Empoweringpts9 @DCharabaty @ownyourcrohns @crohnsbabble @LivingWithUmeed @vkckiranpullela @TheMaveilousGut @dunung_ruchita #MondayNightIBD #PatientExperience
#IBDPoll 2️⃣
🧐Thinking about your culture’s expectations
📊 Have you tried Complementary and Alternative (CAM) Therapies (ex: ayurveda, homeopathy)?
What drove you to try these therapies? Please share your experience.
SE=side effects
#IBDPoll 2️⃣
🧐Thinking about your culture’s expectations
📊 Have you tried Complementary and Alternative (CAM) Therapies (ex: ayurveda, homeopathy)?
What drove you to try these therapies? Please share your experience.
SE=side effects
@MondayNightIBD @southasianIBD @ibdesis @Empoweringpts9 @DCharabaty @ownyourcrohns @crohnsbabble @LivingWithUmeed @vkckiranpullela @TheMaveilousGut @dunung_ruchita Thank you @MondayNightIBD for shining a spotlight on 🌏 #SouthAsianIBD pt experience!
I'm Madhura from 🇮🇳, co-founder Team @ibdesis. We are proud to lead #PatientExperience on #MondayNightIBD!
We hope to improve care for our community around the 🌍 through @SouthAsianIBD.
I'm Madhura from 🇮🇳, co-founder Team @ibdesis. We are proud to lead #PatientExperience on #MondayNightIBD!
We hope to improve care for our community around the 🌍 through @SouthAsianIBD.
1/ OK, so today #OBGynInternChallenge diagnosed an ectopic! What do you do once that's accomplished? Let's talk about treatment with a #tweetorial! We'll do these occasionally to cover content we couldn't get to in our @learnarist course. Bonus knowledge! #MedEd #FOAMed #FOAMob
2/ When you think about #treatment for any medical condition, it can be helpful to organize your thoughts into three broad categories: #medical, #surgical, and #expectant. We often forget about that last one! #MedTwitter #OBGynTwitter
3/ With #ectopic #pregnancy, #surgery is what you probably think of first. It's appropriate in three cases: 1) hemodynamically unstable patient; 2) a patient who desires surgery instead of medical therapy; 3) a patient has a contraindication to medical therapy.
