Discover and read the best of Twitter Threads about #posaconazole
Most recents (4)
Images of Infectious Diseases
46F with diabetes presents with orbital apex syndrome. Imaging and histopathology shown. What is your differential diagnosis? #MayoIDQ to follow @StephanieGrach @ZYetmar @omarabusaleh15
46F with diabetes presents with orbital apex syndrome. Imaging and histopathology shown. What is your differential diagnosis? #MayoIDQ to follow @StephanieGrach @ZYetmar @omarabusaleh15
2/ #MayoIDQ
46F with uncontrolled DM and recent DKA is admitted because of left sided HA for a month. PE: orbital apex syndrome. Head imaging shown. ENT/neurosurgery proceeded with debridement. Pathology shown. Which one of the following choices is most correct?
46F with uncontrolled DM and recent DKA is admitted because of left sided HA for a month. PE: orbital apex syndrome. Head imaging shown. ENT/neurosurgery proceeded with debridement. Pathology shown. Which one of the following choices is most correct?
3/
Case diagnosis: Rhinocerebral #mucormycosis due to #Rhizopus in a person with poorly controlled diabetes mellitus
Rx:
Surgical debridement
Liposomal #Amphotericin B
Later: transitioned to #Posaconazole upon clinical control and improvement
Case diagnosis: Rhinocerebral #mucormycosis due to #Rhizopus in a person with poorly controlled diabetes mellitus
Rx:
Surgical debridement
Liposomal #Amphotericin B
Later: transitioned to #Posaconazole upon clinical control and improvement
JUST IN |An online application system for allotment of #LiposomalAmphotericinB, #Posaconazole and Isavuconazole, is introduced by #Telangana govt @Shiva_THNews
Steps involved---
Application for the #LiposomalAmphotericin B, Posaconazole and Isavuconazole, should be sent in a prescribed proforma to ent-mcrm@telangana.gov.in
Application for the #LiposomalAmphotericin B, Posaconazole and Isavuconazole, should be sent in a prescribed proforma to ent-mcrm@telangana.gov.in
“The applications will be scrutinized by a committee consisting of Director of Medical Education (DME) @DMETELANGANA, Superintendent of ENT Hospital, and HoD of Department of ENT, Gandhi Medical College,” as per a press note.
Finally got to analyze & put my thoughts together on the recent #posaconazole vs. #voriconazole phase 3 trial for invasive #aspergillosis published in .@TheLancet a few weeks ago.
Best is to put the major trials of the 3 #VIP triazoles done over the last 20 years in perspective!
Best is to put the major trials of the 3 #VIP triazoles done over the last 20 years in perspective!
So (re)studied the following key trials & appendices
#Posaconazole vs. #Voriconazole: thelancet.com/journals/lance…
#Isavuconazole vs. Vori: thelancet.com/journals/lance…
#AmphotericinB vs. Vori: nejm.org/doi/10.1056/NE…
#TxID #IDTwitter
#Posaconazole vs. #Voriconazole: thelancet.com/journals/lance…
#Isavuconazole vs. Vori: thelancet.com/journals/lance…
#AmphotericinB vs. Vori: nejm.org/doi/10.1056/NE…
#TxID #IDTwitter
Here is the table with key points of trial design of the #TresAmigos trials, interesting features:
#Vori-Ampho was open label, but with blinded adjudication, including to adverse effects.
All where non-inferiority trials, #vori-amphoB had a clause for claiming superiority.
#Vori-Ampho was open label, but with blinded adjudication, including to adverse effects.
All where non-inferiority trials, #vori-amphoB had a clause for claiming superiority.
On day 14 of neutropenia, an astute ID fellow noted this finding (photo) while examining a patient with fever. Underlying AML and ongoing chemotherapy.
What do you suspect? What work up do you suggest? Details and #MayoIDQ MCQ to follow...
What do you suspect? What work up do you suggest? Details and #MayoIDQ MCQ to follow...
65M acute myeloid leukemia. Rx: CLAG-M. Prophy ACV, posaconazole, Levo, inhaled pentamidine
D14 neutropenia: fever / chills
Exam: onychomycosis, rapidly evolving lesions in arms and torso (photo)
You asked for skin biopsy. Blood culture will grow what fungus?
D14 neutropenia: fever / chills
Exam: onychomycosis, rapidly evolving lesions in arms and torso (photo)
You asked for skin biopsy. Blood culture will grow what fungus?
2/
Case diagnosis: disseminated fusariosis
Majority got the diagnosis correctly!
Blood culture: Fusarium sp.
Rx: AmBisome / voriconazole
Hope for neutrophil recovery!!!
Case diagnosis: disseminated fusariosis
Majority got the diagnosis correctly!
Blood culture: Fusarium sp.
Rx: AmBisome / voriconazole
Hope for neutrophil recovery!!!
