Discover and read the best of Twitter Threads about #AmphotericinB
Most recents (5)
#BombayHighCourt to hear clutch of petitions pertaining to management of #COVID19 in #Maharashtra.
Hearing before Bench of Chief Justice Dipankar Datta and Justice GS Kulkarni.
@CMOMaharashtra
@mybmc
Hearing before Bench of Chief Justice Dipankar Datta and Justice GS Kulkarni.
@CMOMaharashtra
@mybmc
Adv General Ashutosh Kumbhakoni appears for State, ASG Anil Singh appears for Centre, Sr Adv Anil Sakhare appears for BMC.
Advocates Simil Purohit, Arshil Shah, Rajesh Inamdar, Ajinkya Udane appear for petitioners.
#BombayHighCourt
@ArshilAjay
@rajinamdar22
Advocates Simil Purohit, Arshil Shah, Rajesh Inamdar, Ajinkya Udane appear for petitioners.
#BombayHighCourt
@ArshilAjay
@rajinamdar22
#BombayHighCourt is hearing Suo Motu plea concerning #COVID19 situation in districts falling within the Aurangabad Bench jurisdiction.
Bench of Justices RV Ghuge and BU Debadwar are dealing with the issue of #mucormycosis.
Bench of Justices RV Ghuge and BU Debadwar are dealing with the issue of #mucormycosis.
Court is informed that till today in Aurangabad there have been 49 deaths, and in Nanded 35 deaths.
In Marathwada region, 124 deaths have taken place till date.
#COVID19 #BombayHighCourt
In Marathwada region, 124 deaths have taken place till date.
#COVID19 #BombayHighCourt
Court: And what is the stock of the #AmphotericinB with us?
Because the affidavit in the Principal seat says about 5-6 vials are required in a day, and we were told yesterday that only 1-2 vials in a day. SO what is it? Undertreatment?
#COVID #BombayHighCourt
Because the affidavit in the Principal seat says about 5-6 vials are required in a day, and we were told yesterday that only 1-2 vials in a day. SO what is it? Undertreatment?
#COVID #BombayHighCourt
Delhi High Court will today continue hearing petitions concerning #COVID19 issues in the national capital.
Hearing to take place before Justices Vipin Sanghi and Jasmeet Singh.
#DelhiCovid
@CMODelhi @LtGovDelhi
Hearing to take place before Justices Vipin Sanghi and Jasmeet Singh.
#DelhiCovid
@CMODelhi @LtGovDelhi
This was issue related to judicial officers.. court had directed a meeting. Significant developments have happened: Senior Adv Dayan Krishnan for Delhi Judicial Officers Association.
Things are adequate.. govt has appointed Principal Secretary (Law) as nodal officer; Krishnan
Things are adequate.. govt has appointed Principal Secretary (Law) as nodal officer; Krishnan
The only small issue is with respect to declaration of frontline workers. They have been declared as frontline for vaccination only. If there are any other benefits, that should also accrue to us. That needs to be looked into by govt : Krishnan
#DelhiHighCourt
#DelhiHighCourt
#Gujarat declared #Mucormycosis an epidemic and made it a notifiable disease on May 20, but...
This should've been done much, much earlier and still, gaps remain.
A Thread.
This should've been done much, much earlier and still, gaps remain.
A Thread.
Centre says Health is a state subject & yet, #Gujarat the state burdened most with #Mucormycosis in India, waited for an appeal from the GoI before deeming it an epidemic & making it notifiable.
Rajasthan, Telangana, Tamil Nadu, Odisha & Haryana did this before the letter.
1/n
Rajasthan, Telangana, Tamil Nadu, Odisha & Haryana did this before the letter.
1/n
There were 1,237 active #Mucormycosis patients in six major hospitals of #Gujarat on May 20.
Three days earlier, on May 17, Gujarat had 1,040 cases in these six hospitals.
And still, Mucormycosis was not made notifiable even after the state had the highest cases in India.
2/n
Three days earlier, on May 17, Gujarat had 1,040 cases in these six hospitals.
And still, Mucormycosis was not made notifiable even after the state had the highest cases in India.
2/n
Finally got to analyze & put my thoughts together on the recent #posaconazole vs. #voriconazole phase 3 trial for invasive #aspergillosis published in .@TheLancet a few weeks ago.
Best is to put the major trials of the 3 #VIP triazoles done over the last 20 years in perspective!
Best is to put the major trials of the 3 #VIP triazoles done over the last 20 years in perspective!
So (re)studied the following key trials & appendices
#Posaconazole vs. #Voriconazole: thelancet.com/journals/lance…
#Isavuconazole vs. Vori: thelancet.com/journals/lance…
#AmphotericinB vs. Vori: nejm.org/doi/10.1056/NE…
#TxID #IDTwitter
#Posaconazole vs. #Voriconazole: thelancet.com/journals/lance…
#Isavuconazole vs. Vori: thelancet.com/journals/lance…
#AmphotericinB vs. Vori: nejm.org/doi/10.1056/NE…
#TxID #IDTwitter
Here is the table with key points of trial design of the #TresAmigos trials, interesting features:
#Vori-Ampho was open label, but with blinded adjudication, including to adverse effects.
All where non-inferiority trials, #vori-amphoB had a clause for claiming superiority.
#Vori-Ampho was open label, but with blinded adjudication, including to adverse effects.
All where non-inferiority trials, #vori-amphoB had a clause for claiming superiority.
