Discover and read the best of Twitter Threads about #NOAC

Most recents (7)

1/

Second day of @Smart_Meeting_M

Professor @giovannilandoni talking about management of #anticoagulant in #perioperative patients 💉

✅You surely all know how to deal with #antithrombotic and #regionalanesthesia, here the guidelines:

pubmed.ncbi.nlm.nih.gov/34980845/

#FOAMed #FOAMcc Image
2/

💡Let's focus on perioperative #DOAC /#NOAC / #TSOAC

➡️Consider both #surgical blood loss risk and #patient characteristics.

⚠️Remember NOT to bridge with #LMWH or #UFH.

pubmed.ncbi.nlm.nih.gov/33895845/ Image
3/

What if it's not an elective patient??

Use #reversal agents when needed❗

🔹#Idarucizumab for #dabigatran
🔹#Andexanet for #apixaban and #rivaroxaban
💡#Prothrombin complex concentrates in addiction

pubmed.ncbi.nlm.nih.gov/36988142/ Image
Read 7 tweets
La FA es la arritmia mas común en #Amyloidosis #Cardiaca ya que existe una predisposición en el depósito de fibras amyloides en el atrio y en adición a un aumento de las presiones intra-atriales, resultando una dilatación.
🚩: FA + Bajo Voltaje + LVH Image
Un 33% de estos pacientes presentaron trombo intracardiaco en autopsias, con un riesgo elevado de #shock cardiogenico.
El tratamiento es poco tolerada, ya que pueden provocar un estado de bajo gasto cardiaco y deterioro hemodinámico, por la fisiología restrictiva de la #AC

◼️Rythm: Amiodarona y Dofetilide

◻️Rate: bajas dosis de #BetaBlockers

🔲La ablacion por catéter a tenido grandes avances
Read 6 tweets
Don’t miss a new accredited #tweetorial launching TOMORROW here on @cardiomet_CE. #Emergencymedicine #thrombosis researcher @md_pollack will be discussing safe, effective management of selected patients with venous thromboembolism (#VTE) from the #emergencydepartment.
It used to be SOOO much more complicated, but since we entered the era of the #DOACs, #lifeisgood! #Physicians #nurses #pharamcists all work together to make it happen, and all can earn CE/#CME here! @AlexSpyropoul @ScottKaatz @RenatoDLopes1 @GenoMerli @aakonc @vic_tapson
1) Welcome to a #tweetorial on the safe and effective management of acute venous #thromboembolism (#VTE) directly from the #emergencydepartment. This program is accredited for 0.50 credits for #physicians #nurses #pharmacists by @academiccme! I am @md_pollack. Image
Read 23 tweets
Patients with #HF are at risk for thromboembolic events,even when in sinus rhythm

Low-dose #DAOC seem to reduce thromboembolic risk

OAC should be considered in patients with heart failure in sinus rhythm in some circumstances jacc.org/doi/10.1016/j.… @JACCJournals #cardiotwitter
Patients with heart failure should be evaluated for atrial fibrillation or subclinical atrial tachyarrhythmias. Decision to anticoagulate depends on the CHA2DS2-VASc score. #MedTwitter
Heart failure patients in sinus rhythm with a mechanical heart valve, active venous thromboembolism, or hypercoagulable disorder should be anticoagulated. #CardioTwitter @JACCJournals @JavedButler1 @MihaiTrofenciuc
Read 5 tweets
1/
Ever wonder if all #DOACs were created equal? #GITwitter #livertwitter #MedTwitter

Let's start with a poll followed by a #tweetorial on direct oral anticoagulants. First things first, which is your go-to choice of #DOAC ? (COI: none):
2/
These agents work "directly" to anti-coagulate and since they are hardly "new' anymore the term #NOAC has become obsolete. Dabigatran is a direct thrombin inhibitor (factor IIa), whereas the others are factor Xa inhibitors (note the Xa in their names)

3/
In general they share many characteristics such as a quick onset of action, shorter half-lives, potential for drug-drug interactions (CYP3A4 & P-gp) and renal elimination (except apixaban) when compared with warfarin

ncbi.nlm.nih.gov/pmc/articles/P…
Read 18 tweets
For people >= 80 years of age with non-valvular #AF, once-daily #edoxaban 15mg was superior to placebo in preventing #stroke or systemic embolism & did not result in a higher incidence of major #bleeding than placebo
| #AFib #Elderly #NOAC 🇯🇵 @NEJM nejm.org/doi/full/10.10…
Participants were elderly Japanese patients (≥80 years of age) with nonvalvular #AtrialFibrillation who were not considered to be appropriate candidates for oral #anticoagulant therapy at doses approved for #stroke prevention.
Read 3 tweets
Study warns against combined use of oral #anticoagulants , #antiplatelet therapy for #AFib 1️⃣

#GARFIELD-AF registry

escardio.org/The-ESC/Press-…
2️⃣ Currently, do you stop #aspirin w #NOAC #DOAC for #AFIB in pts w previous history of stent (>1yr prior) for non-ACS CAD ? (Yes- I know it should be a less and less common scenario)
3️⃣ Currently, do you stop #aspirin w #NOAC #DOAC for #AFIB in pts w previous history of CAD ( #STEMI / #NSTE-ACS >1year prior) ?
Read 3 tweets

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