Discover and read the best of Twitter Threads about #HF

Consejo de Cardiología Clínica y Terapéutica SAC

@clinicasac

📌#Revisión & #Metaanálisis. Revascularización en Cardiopatía Isquémica c/FEY <35%: para quienes y como.
4⃣ECR & 2.4K👥
🔹HEART (#HF #Revascularisation Trial)
🔸STICH (Surgical Treatment for #Ischemic HF)
🔹PARR-2 (PET and Recovery Following Revascularization)
🔸REVIVED-BCIS2

🔹HEART (6%👥) FEY 24%. CABG vs OMT. Viabilidad todos.
🔸STICH/STICHES (49%👥) FEY 28%. CABG vs OMT. Viabilidad discrecional🩺.
🔹PARR-2 (17%👥) FEY 27%. tto guiado x imágenes
🔸REVIVED (28%👥) FEY 27%. PCI vs OMT. 14% TCI y 58% DA prox. Viabilidad todos.
👇Para guardar

📌Rol de la isquemia:
🔸Basado en estudios históricos: MASS II.
🔹STICH (nuclear) no mostró beneficio y sí un pequeño subanálisis del ISCHEMIA (gráfico)
🔸Aún👉recomendación clase I p/👥c/ enf. multivaso + isquemia inducible y FEY severa, aunque la evidencia actual no lo avala⛔️

Read 7 tweets

cardio-met

@cardiomet_CE

1) Welcome to Part 1 of a new #accredited #tweetorial in our series of educational programs on #hypertrophic #cardiomyopathy #HCM. Previous programs, still available for 🆓CE/#CME, are at cardiometabolic-ce.com/category/hcm/.
Now you can earn another 1.5hr credit by following ALL of this 🧵!

2) Our expert author is Sergio Kaiser MD PhD FACC FESC 🇧🇷🇮🇱 @pabeda1, cardiologist 🫀, Professor 🎓 of #InternalMedicine, Rio de Janeiro State University. He brings the general cardiologist's perspective to our #HCM discussions. Read and learn!
#FOAMed #CardioTwitter

3) This program is supported by an unrestricted educational grant from Bristol Myers Squibb. Statement of accreditation and faculty disclosures at cardiometabolic-ce.com/disclosures/. Credit for #physicians #nursepractitioners #physicianassociates #nurses #pharmacists from @academiccme.

Read 68 tweets

Heather Haworth 🇺🇦 🌻 #StandWithUkraine 💜🏳️‍🌈

@HeatherHawort17

1/ #OPSEC STOP ALL CONTRACTS w/ #Palantir (Boldend) - Peter Thiel, FB #Fascism #DarkMoney

THIEL - Musk, Koch #KochNetwork Milo, Ton-That, Giesea, Thiel protégé, Cernovich, Breitbart & T. $ startup “White Nationalist Hate Group” & Palantir pushed by Flynn huffpost.com/entry/clearvie…

https://twitter.com/cnn/status/1629841492859650048

2/ “Pence again spoke at #HF DC of #KochNetwork”

#Koch & White Nationalist Hate Groups Bankrolled by #DonorsTrust prominent conservative #DarkMoney fund favored by #GOP - #Koch Mercer & Devos biggest known backer of 2 #WNHG #Fascism $ #Jan6 #DISCLOSEAct exposedbycmd.org/2022/06/07/buf…

3/ Koch advocacy group courts far-right Republicans it vowed to thwart
Americans for Prosperity Action (AFP - Koch family political network - #KochNetwork)
recently invited two politicians who tried vigorously to overturn the 2020 presidential election theguardian.com/us-news/2023/f…

Read 4 tweets

cardio-met

@cardiomet_CE

1a) Welcome to a new #accredited #tweetorial, “MOA and Clinical Trial Data for Novel & Emerging Therapeutic Strategies for #HCM: Can We Target Our Therapy?"

1b) Our expert (and returning @cardiomet_ce) author is Giuseppe Galati MD, MMSc in Heart Failure, FHFA, @GiuseppeGalati_ , Consultant #Cardiologist #HeartFailure & #Cardiomyopathies

2) @GiuseppeGalati_ is in Milan 🇮🇹 This program is intended for #healthcare professionals & is accredited for 0.75h CE/#CME credit for #physicians #physicianassistants #nurses #nursepractitioners #pharmacists.

Read 46 tweets

Neal Dixit, MD

@NealDixit

A 🧵on STRONG-HF 💪🏾🫀

⭐️The first randomized trial to show the immense benefits of a comprehensive high-intensity med-titration program with #HF GDMT

❓How did the investigators achieve an 8.1% ARR in HFH/mortality at 6 months❓

Let’s see what we can learn 👇🏾🧵

First let’s take a look at the inclusion and exclusion criteria.

You’ll note:
👉🏾must have SBP > 100, HR >60, K <5.0, GFR > 30
-this eliminates many patients unlikely to tolerate aggressive titration

At baseline still a sick cohort:
-66% NYHA 3 or more
-avg NT-proBNP 7110

Next we see what they aimed for

✌🏽Half doses at discharge

✊🏽Full doses by week 2

And these were high guideline directed target doses e.g.:
-Carvedilol 50 BID
-Spironolactone 50 qd
-Enalapril 20 BID (👀)
-S/V 97/103 BID

Read 7 tweets

Consejo de Cardiología Clínica y Terapéutica SAC

@clinicasac

#AHA22. DESTACADOS DÍA 1⃣📚.
🧵Seguilo hasta el final.

⛔️DCP trial:
💊Clortalidona vs Hidroclorotiazida.
👥13K hipertensos a 2.5 años.

🏁Resultados: ⛔️sin diferencias significativas en pto final combinado (muerte, IAM, IC stroke, revascularización, muerte -no por cáncer-).

⛔️TRANSFORM-HF:
💊Torsemida vs Furosemida vía oral en #HF
👥2.8 k 🏥con IC descompensada aleatorizados a furosemida vs torsemida después del alta.
🗓️Seguimiento medio 17 meses.

🏁Resultados: ⛔️sin diferencias en mortalidad por todas las causas u hospitalizaciones🏥.

⛔️IRONMAN.
👥1.1K. Fe derisomaltose IV vs plcbo en #HFrEF.
📋Inclusión: FEVI ≤45%, NYHA II–IV, sat. d transferrina <20% o ferritina <100 μg/L, reciente🏥x IC y NTBNP >250 (RS)/> 1000 (FA)

🏁Resultados:⛔️sin diferencias significativas en pto final de muerte CV y🏥por IC.

Read 5 tweets

Viet Le PA-C, FACC FAHA

@VietHeartPA

TRANSFORM-HF

What do we really know about efficacy of furosemide vs torsemide?

I am sure @robmentz and team have something to say about this 👊🏾

pubmed.ncbi.nlm.nih.gov/33714745/

#AHA #LBCT @AHAScience @noshreza

Chlorthalidone versus HCTZ - pragmatic emr study by @Areefishani et al. After #SPRINTTrial I use chlorthalidone. What’s the evidence?

pubmed.ncbi.nlm.nih.gov/35390512/

#AHA #LBCT @AHAScience @noshreza

PPAR-alpha (e.g., fenofibrate, permafibrate) - Are triglycerides as a target out for CV event reduction, or just this mechanism?

pubmed.ncbi.nlm.nih.gov/30342298/ @APradhanBrigham to present 👊🏾

#AHA #LBCT @AHAScience @noshreza

Read 8 tweets

@CKD_ce

@ckd_ce

1) Welcome to this new #accredited #tweetorial on “Strategies to Apply Current Clinical Trial Data for SGLT2i to Reduce the Progression of CKD,” authored by our ⭐️tweetorialist Edgar V. Lerma 🇵🇭 @edgarvlermamd

2) This program is #accredited for CE/#CME #physicians #physicianassociates #nurses #pharmacists #nursepractitioners & is supported by an educational grant from the Boehringer Ingelheim Pharmaceuticals Inc and Eli Lilly Company. It is intended for healthcare professionals.

3) Faculty disclosures and statement of accreditation are provided at ckd-ce.com/disclosures/. Please FOLLOW @ckd_ce (& @cardiomet_CE!) so you don't miss ANY of our unique serialized #tweetorials, always 🆓, always from expert authors! Prior programs at ckd-ce.com/category/dkd/ .

Read 26 tweets

cardio-met

@cardiomet_CE

1) Welcome to a new #accredited #tweetorial, Update on New HFrEF Data from ESC 2022 with a Focus on Vericiguat. Our expert author is Giuseppe Galati MD, MMSc in Heart Failure, FHFA, @GiuseppeGalati_ , Consultant #Cardiologist #HeartFailure & #Cardiomyopathies

2) @GiuseppeGalati_ is at San Raffaele Research Hospital, Milan 🇮🇹 @SanRaffaeleMI. This program is intended for #healthcare professionals & is accredited for 0.75h CE/#CME credit for #physicians #physicianassistants #nurses #nursepractitioners #pharmacists.

3) This program is supported by an educational grant from Bayer. See archived programs still open for credit at cardiometabolic-ce.com. Statement of accreditation & faculty disclosures at cardiometabolic-ce.com/disclosures/.🙏 FOLLOW US !

Read 43 tweets

Henry Han , MBBS, MD

@HanCardiomd

#COAPT Risk Score for Death or #HeartFailure 🏥

📍Simple risk score using 4 clinical (COPD, #NYHA class, Afib/Aflut, and #CKD)

📍4 #EchoFirst (#LVEF, LVESD, RVSP, and #TR) variables + 1 treatment-related variable (#TEER)

jacc.org/doi/10.1016/j.… @JACCJournals @GreggWStone

Using data from the #COAPT trial, a simple risk score using 4 clinical and 4 Echo parameters + 1 treatment-related variable (#TEER), which provides prognostic insight into the 2-year rates of ☠️ or #HeartFailure 🏥 in patients with symptomatic #HF and severe #FMR

@JACCJournals

There was consistent benefit from TEER with MitraClip across all risk strata

FMR and HF pts are at ⬆️ risk for ☠️ and recurrent HFH, despite best Med Rx & invasive Tx including MV TEER

👉🏻Future studies are needed to externally validate the COAPT risk score in pts with HF & FMR

Read 6 tweets

Heather Haworth 🇺🇦 🌻 #StandWithUkraine 💜🏳️‍🌈

@HeatherHawort17

ONE has tried to stop #Koch since 1930s. US allowed Fred Koch to come back AFTER working for Stalin & Hitler. Steralization of #LGBT+ w/ ADF & SCOTUS #Barrett

#KochNetwork funded #Jan6 #Insurrection of #Fascism #DarkMoney

#USandTheHolocaustPBS
👉unkochmycampus.org/los-ch3-part-1…

https://twitter.com/cbsmornings/status/1570030964352643072

1929-31 Fred Koch #KochNetwork Soviet Union building oil refineries for Stalin & Hitler Nazi Germany prior to WWII. Russia 1956 & Iraq 1958 just prior to Iraq Coup/Revolution. Prior to Soviet Union, worked in England. FBI Docs 👉 america.aljazeera.com/articles/2014/… 👉 assets.documentcloud.org/documents/1237…

Iran-Contra Koch & Hayek Mont Pelerin Society member since 1970 - Pinochet & CLOSE ties to Milton Friedman direct help & Hayek several visits to Chilea late 70s & early 80s - specifically defended Pinochet’s regime & Peter Thiel
MISES #KochNetwork

unkochmycampus.org/los-ch2-part-4…

Read 15 tweets

@CKD_ce

@ckd_ce

1) Welcome to a new #accredited (0.75h CE/#CME) #tweetorial on challenging case presentations for pts with #cardiometabolic disease, #CaReMe #FOAMed.
Our expert author is Claire Davies. @claireyrivs is a specialist diabetes & endocrinology #pharmacist working in Gateshead in 🇬🇧.

2) She is a member of UKCPA Diabetes & Endocrinology committee @UKCPADiabetes & works across #diabetes, #endocrinology, & emergency/acute care in Secondary Care. She is currently involved in development of regional guidelines & education to support medicines optimisation for PLWD

3a) This program is intended for healthcare professionals and is supported by an educational grant from Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company.

Read 36 tweets

@CKD_ce

@ckd_ce

1) Welcome to our new #accredited #tweetorial which is Part 1 of a 2-part "highlights" program on new #SGLT2i & #DKD data presented at @ERAkidney #ERA22. #Physicians #nurses #pharmacists #PAs and #NPs can all earn 0.5h CE/#CME by following this thread!

2) @ERAkidney #ERA22 is a primary international scientific symposium for interaction and exchange among basic scientists and clinicians working in #Nephrology. It was held in May. Our expert author is Dr. Sheila Bermejo (@shbermejo) from @vallhebron in Barcelona, Spain.

3) This program is #accredited for CE/#CME & is supported by an independent educational grant from the Boehringer Ingelheim/Lilly Alliance. It is not intended for US- or UK-based based HCPs. Accreditation statement & faculty disclosures at ckd-ce.com/disclosures/.

Read 43 tweets

Dominique Vervoort

@DVervoort94

Today marks the start of #WHA75!

This week, @WHO, Ministries of Health, civil society, & more will discuss #GlobalHealth priorities.

Missing on agenda? #GlobalSurgery & 🫀 care.

Hence, I'll be sharing key points, papers, & developments in #GlobalCardiacSurgery in 75 tweets 👇

(1/75) To start, what *is* #GlobalCardiacSurgery?

GCS extends far beyond OR, from community-based disease detection & efficient referral networks to timely care, long-term follow-up, robust supply chains & adequate financial risk protection. #WHA75

Read: academic.oup.com/ejcts/article/…

(2/75) Why does #GlobalCardiacSurgery matter?

⚠️ Every year, 18 million people die from #CVD

🫀 500 million live with CVD; 100s of millions more to come.

🏥 Up to 1/3 will require #CTSurgery or interventional care in lifetime

Data @IHME_UW: healthdata.org/results/data-v…

#WHA75

Read 77 tweets

@CKD_ce

@ckd_ce

1) Welcome to our #accredited #tweetorial on optimal mgt of #hyperkalemia in the patient with #CKD. Earn 0.5h #CME/CE credit by following this thread. I am Sourabh Sharma MD DNB FASN 🇮🇳 @iamnephrologist & u have found the ONLY source for CE credit delivered entirely on Twitter!

2) This program is supported by educational grants from AstraZeneca and Bayer & is intended for #healthcare providers. See faculty disclosures ckd-ce.com/disclosures/. Educational credit for #physicians #physicianassociate #nurses #nursepractitioners #pharmacists 🇺🇸🇨🇦🇪🇺🇬🇧

3) Potassium was first isolated by Humphry Davy in 1807 by electrolysis (Coined word from “Potash” [Dutch]). The periodic table symbol K was derived from kali (alkali) [Arabic].
en.wikipedia.org/wiki/Potassium
#NephroNotes #NephPearls #FOAMed #MedEd @MedTweetorials #CardioTwitter

Read 36 tweets

cardio-met

@cardiomet_CE

1) Welcome to a new #accredited #tweetorial, Prevention and Management of Heart Failure in T2 Diabetes: The Cardiologist’s Perspective! Our expert author is Giuseppe Galati MD, MMSc in Heart Failure, @GiuseppeGalati_ , Consultant #Cardiologist #HeartFailure & #Cardiomyopathies

3) @cardiomet_CE is supported by educational grants from AstraZeneca, Bayer, Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company, & Chiesi. Earn credit from archived programs at cardiometabolic-ce.com. Disclosures at cardiometabolic-ce.com/disclosures/.🙏 FOLLOW US !

Read 56 tweets

cardio-met

@cardiomet_CE

1) Welcome to a new #accredited #tweetorial, Prevention and Management of Heart Failure in T2 Diabetes: The Diabetologist’s Perspective! Our expert author is Melanie J Davies CBE FMedSci @profmjdavies, Prof of Diabetes Medicine, U Leicester, Leicester Diabetes Unit @LDC_Tweets

2) This program is intended for #healthcare professionals and is accredited by @academiccme for 0.75h CE/#CME credit for #physicians #physicianassistants #nurses #nursepractitioners #pharmacists 🇺🇸🇨🇦🇬🇧🇪🇺. FOLLOW US for #cardiometabolic education from expert authors!

3) @cardiomet_CE is supported by educational grants from AstraZeneca, Bayer, Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company, and Chiesi. See archived programs still available for credit at cardiometabolic-ce.com. Disclosures at cardiometabolic-ce.com/disclosures/

Read 43 tweets

cardio-met

@cardiomet_CE

2) This program is supported by educational grants from AstraZeneca, Bayer, & Chiesi & is intended for #healthcare providers. See faculty disclosures cardiometabolic-ce.com/disclosures/. Educational credit for #physicians #physicianassociate #nurses #nursepractitioners #pharmacists 🇺🇸🇨🇦🇪🇺🇬🇧

3) Potassium first isolated by Humphry Davy in 1807 by electrolysis (Coined word from “Potash” [Dutch]). The periodic table symbol K was derived from kali (alkali) [Arabic].
en.wikipedia.org/wiki/Potassium
#NephroNotes #NephPearls #FOAMed #MedEd @MedTweetorials #CardioTwitter

Read 36 tweets

@CKD_ce

@ckd_ce

1) Welcome to a new #accredited #tweetorial on Cardiorenal Disease in T2D & the Impact of Blocking the MR in Patients w/DKD, another CE/#CME program by one of the @GoggleDocs, this time our friend @AmarPut, Diabetes & Endocrine Consultant in the West Midlands 🇬🇧. #CaReMe #FOAMed

2) This program is supported by an educational grant from Bayer & is intended for #healthcare providers. Author disclosures can be found at ckd-ce.com/disclosures/. Prior programs, still available for CE/#CME credit, are at ckd-ce.com. CE/#CME credit 🇬🇧🇪🇺🇨🇦🇺🇸

3) So first – the ‘triple threat’ . . . We know of the link between the 🫀 and the kidneys and the ‘#cardiorenal’ syndrome, but what about in the setting of #diabetes?

Read 55 tweets

Giuseppe Galati

@GiuseppeGalati_

🎖 #ACC_AHA_HFSA #HF Guidelines are out
Short Tweetorial
🍀 Congrats to the authors for the huge effort : 108 pgs covering multiple aspects including #CardiacAmyloid
@ShelleyZieroth @hvanspall @carlosguizars @ValleAlfonso @JavedButler1 @gcfmd @JJheart_doc
rb.gy/ocnlb7

1️⃣ #HFrEF tx
✅ Pros: Clear 4 pillar 1st line 1 day ( No wait)
❌ Cons: NYHA is not fixed very changeable : Better using Hypotension (SBP<100 mmHg) as choice criteria for ACE/ARB vs ARNI
❌ Cons: After 1 + 1/2 year from #GALACTIC_HF Omecamtiv Mecarbil still not in GD

2️⃣ #HFmrEF
✅ Pros: Concur with HFmrEF recom.
⭕️ Probably a 2a in this class for #ARNI is more EBM
@DrNasrien @dranulala @robmentz @MicheleSenni @DrDEliaEmilia @gbiondizoccai @torresviera @JavierdeJuan1 @global_meded @Filippatos @YuriLopatin1
#ACC22

Read 6 tweets

Lorenzo Azzalini

@LAzzaliniMD

1️⃣ Variability in #CAD testing for pts with new-onset heart failure #HF

Prevalence of CAD is 50-60% in HF.

Only 35% of pts underwent CAD testing (21% coronary angiogram) during the 90 days before and after initial HF diagnosis, and 9% underwent revasc.

jacc.org/doi/10.1016/j.…

2️⃣ Pts who underwent CAD testing were more likely to be younger, male, and have systolic dysfunction.
Significant social disparities: CAD testing was used less in women and Black pts.

3️⃣ Pts managed by a cardiologist were more likely to undergo CAD testing, compared with those managed by a PCP (57% vs. 16%; aOR 5.12). However, great variations across cardiologists, as well as across US regions.

Read 5 tweets

Discover and read the best of Twitter Threads about #HF

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Discover and read the best of Twitter Threads about #HF

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