Discover and read the best of Twitter Threads about #babesia

Most recents (5)

Joseph Burrascano, MD - Diagnostic Tools
#Lyme Clinical Presentation: nonspecific, viral-like symptoms that persist, & new ones appear. Then symptoms more focused on musculoskeletal, peripheral and central nervous systems, heart and skin. Muti-systemic & migratory. #ILADS2022 Image
2/Burrascano: Sorting out the co-infections #NotJustLyme #Bartonella #Babesia #Ehrlichia #Anaplasma #Mycoplasma #ILADS2022 ImageImageImageImage
3/Burrascano: Types of tests
SEROLOGIES are indirect, B-cell based tests:
B-cells create antibodies and serologies measure these antibodies #ILADS2022
Read 19 tweets
Joseph Burrascano, Jr. MD: Ticks are "Nature’s Dirty Needle." In addition to #Lyme, ticks may be infected with #Babesia #Bartonella #Ehrlichia #Anaplasma #Chlamydia #Mycoplasma #WestNileVirus #Nematodes #candida and viruses. #ILADS2022
2/Burrascano: B. microti and B. duncani (also known as WA-1) are the predominant cause of Babesiosis in the United States #Babesiosis has been detected in all 50 states #ILADS2022
3/Burrascano: #Babesia odocoilei has been found in ticks across N America, but not human samples, perhaps due to defective primers. Immunoblot data shows significant % of Babesia species in human patients are not microti or duncani. Could be divergens and/or odocoilei? #ILADS2022
Read 8 tweets
I’m noticing many friends, colleagues, acquaintances developing strange, new symptoms yet not attributing them to Covid.

This is eerily reminiscent of my experience w #Lyme; migrating, hard-to-describe, bizarre symptoms that no one has answers for that you just pray will stop.
I feel strongly this needs to be addressed and that the medical world needs to consider not only persistent Covid, but other common reactivated infections other than EBV. The # of tick-borne disease pts who crashed after Covid but got better w retreated shld not be discounted.
I would have my docs look for common persistent pathogens like #Lyme, #bartonella, #EBV, #babesia, etc and treat empirically if symptoms are suggestive w/o + tests, since testing for most of these (not EBV) is terrible.
Read 4 tweets
Images of Infectious Diseases

This is the peripheral blood smear of a 71M s/p splenectomy. Rural Wisconsin. No travel.

CC: fever, sweats, dyspnea
ROS: dark urine
PE: jaundice
Hgb 10. Low haptoglobin.
TBI 3.3 LDH 1075

What is the diagnosis and recommended Rx?
#MayoIDQ MCQ next
1/
71M. WI. (see prior tweet)
S/p splenectomy.
Fever, jaundice, hemolytic anemia.

Your diagnosis: babesiosis (parasitemia 7.3%).

3 days after starting Rx: tinnitus and hypoacusis

What Rx most likely caused this adverse effect?
2/
Treatment of #Babesiosis
1. Atovaquone-azithromycin
2. Quinine-clindamycin

The two regimens have comparable efficacy in non-life-threatening babesiosis.

BUT safety profile of Atovaquone-azithromycin was better

nejm.org/doi/full/10.10…
Read 10 tweets
❗️Just what you’ve been waiting for❗️Sunday @BoggildLab #Tweetorial on Fever in the Returning Traveler!! 🤒✈️🏝🏖💉🦟🌞Buckle up, friends 😊🙏🙏 @MedTweetorials @AcademicChatter #AcademicChatter #MedTweetorials #Fever #Travel #VectorBorneDisease #VaccinesWork 1/23
2/23 Fever = hypothalamic thermostat reset to a ⬆️ temp in response to infection. It’s an adaptive biological response to pathogen invasion that assists w/ immunological control of infections. Most texts refer to fever as temp >38 C. See JAMA paper also: ncbi.nlm.nih.gov/pubmed/1302471
3/23 Fever in returning travelers is common in our population due to high mobility & travel proclivities. We collectively log millions of miles of air and land transit annually to countries that have very different endemicity profiles for infectious diseases compared to 🇨🇦 or 🇺🇸
Read 24 tweets

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