Discover and read the best of Twitter Threads about #avelumab
Most recents (2)
@myESMO #ESMO20 as a #trainee can be #overwhelming! So many good studies, some more #practicechanging then others, if you missed some and want to understand (albeit at a simplistic #trainee level), sit back, relax and enjoy as we go through some great data #ESMO20 @OncoAlert
1. #NSCLC: 2 major studies #ADAURA #CROWN for adjuvant #EGFRmNSCLC, and advanced #ALK+ experts can provide better perspective @JackWestMD @n8pennell @StephenVLiu @AMansfieldMD @CharuAggarwalMD @NarjustDumaMD @GlopesMd @DevikaDasMD @OncoAlert
1. A) #ADAURA: Stage IB-IIIA #resected #NSCLC with #EGFRm treated with #Osimertinib vs #placebo [SOC prior to this was adjuvant chemotherapy [cisplatin-based doublet based on #LACE metanalysis- pubmed.ncbi.nlm.nih.gov/18506026/] showed improvement in #DFS @NEJM nejm.org/doi/full/10.10…
1. My great thanks to @sandrapdangelo & @WTapMD for elaborating on the $250,000 grant they got from @CureSarcoma for uterine #leiomyosarcoma. curesarcoma.org/uterine-leiomy… Their research will help people with other #sarcoma subtypes, too. more ...
2. @sandrapdangelo says grant will go toward 2 immunotherapy #ClinicalTrials. She hopes the first will open @sloan_kettering in late spring. The first will combine a CSF-1R (DCC-3014 deciphera.com/pipeline/dcc-3…) with #avelumab (#Bavencio en.wikipedia.org/wiki/Avelumab). more ...
3. @sandrapdangelo doesn't know when the second #ClinicalTrial will open, but it will combine a PARP inhibitor (en.wikipedia.org/wiki/PARP_inhi…) an immunotherapy drug that has not been chosen yet. "Other #sarcoma subtypes will be allowed to enroll," not just #leiomyosarcoma. more ...
