Discover and read the best of Twitter Threads about #practicechanging

Most recents (2)

Vague and Non-Specific Cancer Symptoms: A short Tweetorial.
A bit of context courtesy of #GP150w for the #blackandwhitechallenge faced in Primary Care:
1/7
Vague and Non-Specific Cancer Symptoms
Continuing the shades of grey, we differentiate the specific cancer signatures from those non-specific symptoms, noting the lowering of the threshold for Positive Predictive Value to the current 3% level.
2/7
Vague and Non-specific Cancer Symptoms
So, what does the evidence for new pathways say?
Quite alot of support for 'gut instinct' or Clinical Suspicion- one of the two commonest reasons for referral to Multi-Diagnostic Centres, and statistically significance to support it.
3/7
Read 8 tweets
@myESMO #ESMO20 as a #trainee can be #overwhelming! So many good studies, some more #practicechanging then others, if you missed some and want to understand (albeit at a simplistic #trainee level), sit back, relax and enjoy as we go through some great data #ESMO20 @OncoAlert
1. #NSCLC: 2 major studies #ADAURA #CROWN for adjuvant #EGFRmNSCLC, and advanced #ALK+ experts can provide better perspective @JackWestMD @n8pennell @StephenVLiu @AMansfieldMD @CharuAggarwalMD @NarjustDumaMD @GlopesMd @DevikaDasMD @OncoAlert
1. A) #ADAURA: Stage IB-IIIA #resected #NSCLC with #EGFRm treated with #Osimertinib vs #placebo [SOC prior to this was adjuvant chemotherapy [cisplatin-based doublet based on #LACE metanalysis- pubmed.ncbi.nlm.nih.gov/18506026/] showed improvement in #DFS @NEJM nejm.org/doi/full/10.10…
Read 19 tweets

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