Discover and read the best of Twitter Threads about #PAH
Most recents (6)
1) Welcome to a 🆕#accredited #tweetorial from @cardiomet_CE! Earn 0.5hr 🆓 CE/#CME by following this 🧵. Our expert faculty is Sanjiv J Shah MD @HFpEF, Cardiologist & Director, Northwestern HFpEF Program (hfpef.org). Director of Research, @NMCardioVasc
#FOAMed
#FOAMed
1b) .@HFpEF will be sharing the algorithm he uses to treat #HFpEF based on evidence we have thus far and his anecdotal experience treating patients over the past 16 years in the @NMCardioVasc HFpEF Clinic.
#CardioTwitter #MedEd @MedTweetorials #HeartFailure
#CardioTwitter #MedEd @MedTweetorials #HeartFailure
2) CE/#CMEcredit for #physicians #physicianassociates #nurses #nursepractitioners #pharmacists 🇺🇸🇨🇦🇬🇧🇪🇺.
Statement of accreditation and faculty disclosures at cardiometabolic-ce.com/disclosures/.
FOLLOW US for accredited programs in #cardiometabolic space delivered wholly on Twitter!
Statement of accreditation and faculty disclosures at cardiometabolic-ce.com/disclosures/.
FOLLOW US for accredited programs in #cardiometabolic space delivered wholly on Twitter!
Proud moment! My First, First Author paper is finally published! Happy Monday News! 🥳
An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis ➡️nature.com/articles/s4200… @CommsBio #PAH #PhD #PhDChat
Here's the Tweetorial👇
An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis ➡️nature.com/articles/s4200… @CommsBio #PAH #PhD #PhDChat
Here's the Tweetorial👇
Inspired by #OrganOnChip technology, we sought to create a model of the pulmonary vascular wall in order to investigate the underlying mechanisms of vascular remodelling in Pulmonary Arterial Hypertension (#PAH).
All of our chips were produced in-house from raw materials.
We created an endothelial-smooth muscle cell interface on our chips and applied laminar fluid shear stress (6 dynes/cm^2) over the endothelial monolayer which enhanced barrier function when compared to static controls.
We created an endothelial-smooth muscle cell interface on our chips and applied laminar fluid shear stress (6 dynes/cm^2) over the endothelial monolayer which enhanced barrier function when compared to static controls.
🚨🚨🚨New @EuroRespSoc @escardio #PulmonaryHypertension guidelines 2022
There is a lot of new guidance, this is just a short thread to begin with the most notable changes...
Let's go! 🧵 👇👇👇 (1/10)
There is a lot of new guidance, this is just a short thread to begin with the most notable changes...
Let's go! 🧵 👇👇👇 (1/10)
1⃣New definition:
📌Same mPAP threshold as Nice 2018 (mPAP> 20 mmHg)
📌Lower PVR threshold (PVR >2 WU)! 👈
📌No more DPG to differentiate Ipc & Cpc
📌Re-introduction of #ExercisePH in definition!👈
(2/10)
📌Same mPAP threshold as Nice 2018 (mPAP> 20 mmHg)
📌Lower PVR threshold (PVR >2 WU)! 👈
📌No more DPG to differentiate Ipc & Cpc
📌Re-introduction of #ExercisePH in definition!👈
(2/10)
2⃣Diagnostic algorithm:
📌Fast track for referral to a #PH centre at any point of warning signs or #PAH or #CTEPH suspected
📌Individualised route for suspected #LungDisease but rapid cross-referral if necessary
📌If eventually PAH/CTEPH suspected, follow to tables 😵💫
(3/10)
📌Fast track for referral to a #PH centre at any point of warning signs or #PAH or #CTEPH suspected
📌Individualised route for suspected #LungDisease but rapid cross-referral if necessary
📌If eventually PAH/CTEPH suspected, follow to tables 😵💫
(3/10)
Technik Teil 2: Wisst ihr eigentlich, dass der #Gepard in weniger als 2,5 Sek seinen Turm um 360° drehen kann? Für den Waffenschwenk von −10° bis +85° in nur 1,5 Sek? Das ist verdammt schnell aber als Besatzung gewöhnt man sich daran. #Heer
Der #Gepard ab B2L (L für Laser) besitzt einen Laserentfernungsmesser. Wird die Laserentfernungsmessung aktiviert, wird die Feuerleitrechnung vereinfacht und beschleunigt. Es wird dadurch mehr Munition verschossen, um die unmittelbare Bedrohung von #PAH oder #Drohnen zu bekämpfen
Ich habe schon mehrfach mit Laser in Todendorf geschoßen. Man muß dabei Schutzmaßnahmen berücksichtigen. Die Umstehenden müssen eine Laserschutzbrille tragen. Wenn das Ziel in den Sendebereich kommt, ändert sich der Frequenzton. Es ist ein abgehaktes Puls-Doppler Geräusch. #Heer
1/20
New in @ATSBlueEditor, the culmination of over 4 years of work in the @bradleymaron lab, in which we identify that #NEDD9 is a hypoxia-regulated pulmonary endothelial protein that directly binds activated platelets to promote pulmonary thrombosis.
atsjournals.org/doi/10.1164/rc…
New in @ATSBlueEditor, the culmination of over 4 years of work in the @bradleymaron lab, in which we identify that #NEDD9 is a hypoxia-regulated pulmonary endothelial protein that directly binds activated platelets to promote pulmonary thrombosis.
atsjournals.org/doi/10.1164/rc…
2/20
The @bradleymaron lab previously discovered that the malignancy protein #NEDD9 promotes endothelial fibrosis by regulating collagen synthesis in human pulmonary artery endothelial cells (HPAECs), which could be targeted to inhibit #PAH in vivo.
stm.sciencemag.org/content/10/445…
The @bradleymaron lab previously discovered that the malignancy protein #NEDD9 promotes endothelial fibrosis by regulating collagen synthesis in human pulmonary artery endothelial cells (HPAECs), which could be targeted to inhibit #PAH in vivo.
stm.sciencemag.org/content/10/445…
3/20
As a pro-metastatic protein, #NEDD9 interacts with pro-thrombotic cell types, & it was shown to be ⬆️ via #HIF1α in cancer cells to promote migration. We hypothesized that #NEDD9 is ⬆️ by hypoxia in HPAECs ➡️ pathogenic platelet-EC adhesion.
cancerres.aacrjournals.org/content/70/10/…
As a pro-metastatic protein, #NEDD9 interacts with pro-thrombotic cell types, & it was shown to be ⬆️ via #HIF1α in cancer cells to promote migration. We hypothesized that #NEDD9 is ⬆️ by hypoxia in HPAECs ➡️ pathogenic platelet-EC adhesion.
cancerres.aacrjournals.org/content/70/10/…
A #MedEd Thread for #pulm #criticalcare #applicants. How do you pick a program? What questions do you ask in a fellowship #interview? Here are some ways programs differ and tagged @IUPCCM experts to answer any questions you may have! #MedTwitter
#PAH: Does Pulm house pulmonary hypertension and manage vasodilator therapy? Or is this managed by a different department? Are there opportunities to learn this if so? @TimLahm @RFPMachado
#IP: Do you have experts performing advanced #bronchoscopy such as #navigational? Does Pulm place stents, valves? Is there #EBUS volume for general fellows to become proficient? How much of this is done by other departments such as Thoracics or ENT? @ChrisKniese
