Discover and read the best of Twitter Threads about #Interferons
Most recents (5)
Daily Bookmarks to GAVNet 09/03/2021 greeneracresvaluenetwork.wordpress.com/2021/09/03/dai…
Unintended Consequences of Air Cleaning Chemistry
pubs.acs.org/doi/10.1021/ac…
#UnintendedConsequences #AirCleaningSystems #ChemicalApplications #SARSCoV2 #AirborneTransmission
pubs.acs.org/doi/10.1021/ac…
#UnintendedConsequences #AirCleaningSystems #ChemicalApplications #SARSCoV2 #AirborneTransmission
You are not the person you were before the pandemic
fastcompany.com/90612974/you-a…
#PandemicResponse #consequences
fastcompany.com/90612974/you-a…
#PandemicResponse #consequences
#location location location: thrilled to share our work @CellCellPress! #interferons dictate #COVID19 severity! Specific #IFNs are produced along the #airways in response to #SARSCoV2 and drive protective or detrimental #transcriptional programs! 1/7 doi.org/10.1016/j.cell…
Can a respiratory #virus infection confer #immunity against the other #respiratory virus? A much-debated issue in the virus immunology for many decades. What is the probable immune mechanism & does it indeed exist? What is the evidence for & against this hypothesis? 1/
It is hypothesized that a respiratory virus infection confers immunity against the same and other respiratory viruses for a short time, perhaps a few weeks. This immunologic mechanism, known as #heterosubtypic ‘temporary non-specific immunity’ 2/
This immune protection is associated with activation of the innate immune response to viral infection mediated by the release of Type I #interferons (IFN) & other cytokines that have broad protective effects against a range of viruses 3/
How does the immune system work? Will there be #COVID19 vaccines? @BioRender & I put together ‘immunology 101 tweetorial for non-immunologists’. @jerryguartist, @shizaoki, @JungHeeSciViz also made this accompanying video. Please share widely! (1/n)
The immune system protects the host from invading pathogens through 2 layers: the innate and adaptive immunity. Innate immunity acts within minutes to remove the pathogen. Adaptive immunity takes days/wks but is specific & long lived, and is the basis for #vaccines. (2/n) 
Innate immunity starts by triggering sensors that detect unusual molecules or activities, known as pattern recognition. Once microbial patterns are detected by these sensors (#PRR), they trigger immediate alarm through secretion of #cytokines and #interferons. (3/n)
An amazing collaborative effort (🇺🇸🇨🇦🇩🇪) where we reveal a new isoform of #ACE2 which we called dACE2! Importantly the shorter, inactive form dACE2, not ACE2, is the form induced by #Interferons and viruses!
biorxiv.org/content/10.110… 1/3
biorxiv.org/content/10.110… 1/3
I remember running that first qPCR to test a hypothesis @prokuninaolsson had, but couldnt test right away since her lab was shut. After a lot of hard work by her group and the whole team, and great zoom meetings, we have learned a lot but still more to understand! 2/3
