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Can a respiratory #virus infection confer #immunity against the other #respiratory virus? A much-debated issue in the virus immunology for many decades. What is the probable immune mechanism & does it indeed exist? What is the evidence for & against this hypothesis? 1/
It is hypothesized that a respiratory virus infection confers immunity against the same and other respiratory viruses for a short time, perhaps a few weeks. This immunologic mechanism, known as #heterosubtypic ‘temporary non-specific immunity’ 2/
This immune protection is associated with activation of the innate immune response to viral infection mediated by the release of Type I #interferons (IFN) & other cytokines that have broad protective effects against a range of viruses 3/
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