Discover and read the best of Twitter Threads about #tangles
Most recents (1)
Are #Amyloid and #Tau #PET positive cognitively unimpaired individuals destined to decline?
Find out in our new preprint: bit.ly/3yXRrOf.
See a thread👇1/11
Find out in our new preprint: bit.ly/3yXRrOf.
See a thread👇1/11
A major unanswered question in the field is whether cognitively unimpaired (CU) individuals who harbor both #Alzheimer’s disease neuropathological hallmarks (abeta #plaques and tau neurofibrillary #tangles) can preserve their #cognition over time or are destined to decline. 2/11
There is fundamental disagreement about the nomenclature. E.g. a CU individual with positive Abeta (A+) and tau (T+) biomarkers is classified as “preclinical AD” by the NIA-AA criteria, while the IWG criteria would label such an individual “at risk for progression to AD”. 3/11
