Discover and read the best of Twitter Threads about #neohematol
Most recents (2)
100 followers!😊 Thanks @MaartenvSmeden for introducing me to twitter. Time for a quick intro. I am an MD who also trained as clinical epidemiologist @LUMC_Leiden. I recently finished my phd in neonatal hematology (defense Jan 31st) @UvA_Amsterdam @amsterdamumc 1/3
Topics: platelet tx, @PlaNeT2_trial, SR, prediction, propensity, HTE). Great team of phd supervisors: @KDraat (pediatric hematologist), Enrico Lopriore (neonatologist), Anske vd Bom (epidemiologist) and Simon Stanworth (hematologist). I am Dutch, married to an Italian-American.
Mom of a boy (3 yr) and girl (3 months). Recently started as a postdoc @sanquin, again in neonatal hematology (#neohematol) Thanks for following, will try to keep you updated on this topic. And thanks for teaching me on other topics as well, learning lots from my twitter feed!
2dary analysis of @PlaNeT2_trial out now. @KDraat @ESteyerberg @Willem_Pieter @BloodJournal #ebneo #FOAMneo #neohematol . A thread. Primary result of trial: more bleeding/death in neonates treated acc to prophylactic platelet tx threshold of 50 comp to 25. 1/3
We reanalyzed the data to look for subgroups of neonates that might benefit from the 50 threshold after all. Instead of using conventional subgroup analyses we used a more robust predicted baseline risk approach. More info? Start reading here: doi.org/10.1136/bmj.k4… 2/3
We did not identify subgroups that benefit from the 50 threshold, though model needs further improvement. Suggests prophylactic platelet tx threshold of 25 appropriate for all preterm neonates, incl those at high risk of bleed/mortality. 3/3 @sanquin @LUMC_Leiden @amsterdamumc
