Discover and read the best of Twitter Threads about #metastatic
Most recents (4)
@TumorBoardTues @shafiarahman_ @RischZack @MPishvaian @ColonCancerCoal @colontown @coloncancermike @GlobalCRC 2/6 #TumorBoardTuesday
Thurs Case🎀
#mCRC & #EGFR tx:
âś…Anti-EGFR useful in RAS/RAF WT; debate re: timing vs anti-VEGF
✅Pt centered discussion including SEs 🗝️
âś…Emerging data: EGFR re-tx, using ctDNA to guide
📚@shafiarahman_ @RischZack’s thread:
threadreaderapp.com/thread/1638330…
Thurs Case🎀
#mCRC & #EGFR tx:
âś…Anti-EGFR useful in RAS/RAF WT; debate re: timing vs anti-VEGF
✅Pt centered discussion including SEs 🗝️
âś…Emerging data: EGFR re-tx, using ctDNA to guide
📚@shafiarahman_ @RischZack’s thread:
threadreaderapp.com/thread/1638330…
@TumorBoardTues @shafiarahman_ @RischZack @MPishvaian @ColonCancerCoal @colontown @coloncancermike @GlobalCRC 3/6 #TumorBoardTuesday
🎥 TBT in a vid- Part 1:
@shafiarahman_ 's approach: pt eligible for EGFR-directed tx in #metastatic #CRC
🔹RAS/RAF WT- more important than side
🔹Bev or pan 1L? Trend toward pan, but is 🗝️actually that pt gets anti-EGFR in tx, 🚫necessarily 1L?
🎥 TBT in a vid- Part 1:
@shafiarahman_ 's approach: pt eligible for EGFR-directed tx in #metastatic #CRC
🔹RAS/RAF WT- more important than side
🔹Bev or pan 1L? Trend toward pan, but is 🗝️actually that pt gets anti-EGFR in tx, 🚫necessarily 1L?
@TumorBoardTues @shafiarahman_ @RischZack @MPishvaian @ColonCancerCoal @colontown @coloncancermike @GlobalCRC 4/6 #TumorBoardTuesday
🎥 TBT in a vid- Part 2:
@shafiarahman_ gives us a preview of what might be coming in #EGFR directed tx in #mCRC
🔹Re-challenge based on ctDNA clearance of resistant clones; pts w resistance to EGFRi benefit later as the tumor evolves again
🔹New combos!
🎥 TBT in a vid- Part 2:
@shafiarahman_ gives us a preview of what might be coming in #EGFR directed tx in #mCRC
🔹Re-challenge based on ctDNA clearance of resistant clones; pts w resistance to EGFRi benefit later as the tumor evolves again
🔹New combos!
@usnehal Dr. Nehal I am holding space for you. My 94-year-old mother lives in VA and was admitted with pneumonia almost 2 weeks ago (COVID-). Long h/o supposed early stage BC but bone/lung mets dx on chest CT. Went to rehab, doing ok, took turn for worse. Readmitted.
@usnehal Now COVID+. ER doc called to confirm my mom’s wishes to be DNR/DNI. She’s 94, with #metastatic cancer. Yes, DNR/DNI, comfort measures. Now on hospice service with death imminent. I’m in CA, with metastatic cancer myself, only 1st shot rec’d. Nurses and docs have called me daily
@usnehal Nurses have facilitated FaceTimes, even using their personal phones, even though my mom is minimally responsive. I cry tears of sadness & guilt that I’m not there, and tears of gratitude for the compassion with which she - and I - are treated. Your mom and you deserve the same.
@myESMO #ESMO20 as a #trainee can be #overwhelming! So many good studies, some more #practicechanging then others, if you missed some and want to understand (albeit at a simplistic #trainee level), sit back, relax and enjoy as we go through some great data #ESMO20 @OncoAlert
1. #NSCLC: 2 major studies #ADAURA #CROWN for adjuvant #EGFRmNSCLC, and advanced #ALK+ experts can provide better perspective @JackWestMD @n8pennell @StephenVLiu @AMansfieldMD @CharuAggarwalMD @NarjustDumaMD @GlopesMd @DevikaDasMD @OncoAlert
1. A) #ADAURA: Stage IB-IIIA #resected #NSCLC with #EGFRm treated with #Osimertinib vs #placebo [SOC prior to this was adjuvant chemotherapy [cisplatin-based doublet based on #LACE metanalysis- pubmed.ncbi.nlm.nih.gov/18506026/] showed improvement in #DFS @NEJM nejm.org/doi/full/10.10…
Let me tell you my 7-Tweet #metastatic #cancer life stage story: I was diagnosed days after turning 50--neither young (tho my oncologist called me young for my diagnosis) nor old. I had children, a husband, plans, a life. My kids were pre-teen and teenagers. 1/
There was nothing (nothing! no books, no support groups, I was too old for YSC and I didn't fit well with the older group either). Just yesterday at #SABCS19, the evening educational program about #metastaticBC over the lifespan excluded anyone who had been a parent of teens...2/
during her diagnosis. This is my #cancer. Teens are trying to sort themselves, to find their place in the world; in short, to separate from their parents. If you think a mom (or dad) getting a Stage IV diagnosis while kids are teenagers doesn't ef up their growth, I'm here 3/
