Discover and read the best of Twitter Threads about #holobionts
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No need for skepticism of #microbiome + virome involvement in #ME/CFS š But we must factor in the activity of organisms (bacteria, viruses, phages, fungi etc) that often persist + interact outside the gutāļøAnd many such organisms are not āgoodā but are pathogens/#pathobionts
In fact, Komaroff asked if anyone has a model for #ME/CFS that links together many findings recently presented at #MECFSatNIH19 š Well, thatās what my recent paper on ME/CFS does!...w/ #microbiome + virome activity central to how separate findings connect:frontiersin.org/articles/10.33ā¦ 
That is b/c š Humans are now understood to be #holobionts: our activity is controlled by the human genome, our microbial/#viral genomes and their respective proteins + metabolites working in tandem (together!): nph.onlinelibrary.wiley.com/doi/full/10.11ā¦
John DuprĆ© kicks off proceedings, giving an intro to the ERC project heās headed at Exeter - which has focussed on the benefits accrued by focussing on processes rather than substances in biological practice
Also tweeting from this event - @LynncChiu
DuprƩ tells a semi-apocryphal story about how he became interested in processes. Markets! All the comings and goings of people and objects in a street market place (for more on this, check out his Spinoza lectures)
