Discover and read the best of Twitter Threads about #Staphylococcus
Most recents (5)
Betten machen im KH lässt #nosokomiale #Keime fliegen - da freut sich der Bettnachbar
#Deutsche Studie weißt #Korrelation zwischen der #Belastung durch #Luft- und #Oberflächenkeime nach dem #Bettenmachen nach - darunter #MRSA
#Deutsche Studie weißt #Korrelation zwischen der #Belastung durch #Luft- und #Oberflächenkeime nach dem #Bettenmachen nach - darunter #MRSA
Ein vorübergehender Anstieg von MRSA in der Raumluft wurde in den meisten Proben 1 Minute und 15 Minuten nach dem Bettenmachen festgestellt, MDRGN wurden in der Luft von zwei Patientenzimmern nachgewiesen.
Beim Bettenmachen verschoben sich die Anteile in Richtung #koagulasenegativer #Staphylokokken und #Staphylococcus #aureus.
1/ Today in @ScienceMagazine, @aspaan1 & colleagues show that human #OTULIN #haploinsufficiency impairs non-leukocytic cell-intrinsic immunity to the #staphylococcal alpha-toxin (science.org/doi/10.1126/sc…).
2/ They discovered OTULIN haploinsufficiency via a genome-wide approach in a cohort of patients with unexplained, life-threatening staphylococcal disease – the findings are relevant in vivo. 
3/ The clinical hallmark of OTULIN haploinsufficiency is necrosis of the skin and/or lungs, typically triggered by infections with #Staphylococcus aureus.
#MayoIDQ: 86M DM
2 wk of R ear pain / nasal discharge
Now: R frontal HA, facial pain, vision loss
PE: R ptosis, CN III, IV, VI palsies, purulence R middle meatus
CT: R sided paranasal sinusitis w/ phlegmonous extension to orbital apex
What is DDx, work up and etiology?
2 wk of R ear pain / nasal discharge
Now: R frontal HA, facial pain, vision loss
PE: R ptosis, CN III, IV, VI palsies, purulence R middle meatus
CT: R sided paranasal sinusitis w/ phlegmonous extension to orbital apex
What is DDx, work up and etiology?
2/
Diagnosis: Orbital Apex Syndrome
S/S due to involvement of structures in orbital apex: most common vision loss and painful / limited eye movement
CN palsies
* Optic nerve
* Oculomotor nerve
* Trochlear nerve
* First division of trigeminal nerve
* Abducens nerve
Diagnosis: Orbital Apex Syndrome
S/S due to involvement of structures in orbital apex: most common vision loss and painful / limited eye movement
CN palsies
* Optic nerve
* Oculomotor nerve
* Trochlear nerve
* First division of trigeminal nerve
* Abducens nerve
3/
DDx (overlapping symptoms) of orbital apex syndrome
1. Cavernous sinus thrombosis
2. Superior orbital fissure syndrome
ncbi.nlm.nih.gov/pmc/articles/P…
DDx (overlapping symptoms) of orbital apex syndrome
1. Cavernous sinus thrombosis
2. Superior orbital fissure syndrome
ncbi.nlm.nih.gov/pmc/articles/P…
A series of images presented by an ID fellow to a faculty panel in the “Challenging Cases” session of the #MayoIDFellowsForum
The fellow asked the experts: What diagnosis comes to mind?
#IDTwitter, what do you think?
Clinical details, #MayoIDQ and MCQ to follow...
The fellow asked the experts: What diagnosis comes to mind?
#IDTwitter, what do you think?
Clinical details, #MayoIDQ and MCQ to follow...
2/
Awesome list of potential pathogens... from staphylococcus / streptococcus to nocardia, TB, fungi (Mucor, Candida, endemics) and toxoplasma, and others.
Without knowing the host and scenario, all are possible. Thank you #IDTwitter.
Now let us learn about the case details..
Awesome list of potential pathogens... from staphylococcus / streptococcus to nocardia, TB, fungi (Mucor, Candida, endemics) and toxoplasma, and others.
Without knowing the host and scenario, all are possible. Thank you #IDTwitter.
Now let us learn about the case details..
3/
45M found unconscious.
PMH: alcohol use disorder. No IDU.
PE: T103F RR32 PR110
Meningismus.
Murmur. Rales.
No skin lesions.
WBC 27K.
Imaging (photo). No PFO.
CSF TNC 9450 /N92% /prot 150 / glu 20
Name the pathogen.
45M found unconscious.
PMH: alcohol use disorder. No IDU.
PE: T103F RR32 PR110
Meningismus.
Murmur. Rales.
No skin lesions.
WBC 27K.
Imaging (photo). No PFO.
CSF TNC 9450 /N92% /prot 150 / glu 20
Name the pathogen.
Images of Infectious Diseases
In addition to these CT findings, there are multiple wedge-shaped peripheral areas of hypoattenuation in the spleen.
Name the host and the risk factor.
In addition to these CT findings, there are multiple wedge-shaped peripheral areas of hypoattenuation in the spleen.
Name the host and the risk factor.
28 PWID. No PMH.
Fever, chills, sweats. cough, abdominal pain x 1 week
PE: ill-looking, murmur, scattered rales, petechiae
WBC 19.5, Cre 2.16
Blood culture: MSSA
CT (prior tweet)
TEE ordered.
Whic of the following options is best for Rx?
Fever, chills, sweats. cough, abdominal pain x 1 week
PE: ill-looking, murmur, scattered rales, petechiae
WBC 19.5, Cre 2.16
Blood culture: MSSA
CT (prior tweet)
TEE ordered.
Whic of the following options is best for Rx?
1/
Case diagnosis:
#MSSA #Endocarditis in #PWID
TEE: TV multiple vegetations + small aortic valve lesion. PFO with small right to left shunt
Case diagnosis:
#MSSA #Endocarditis in #PWID
TEE: TV multiple vegetations + small aortic valve lesion. PFO with small right to left shunt
