Discover and read the best of Twitter Threads about #Monocytes
Most recents (5)
How COVID actively suppresses and evades your immune system [Part 2]
Part 2 looks at how mild and moderate #COVID infection reprograms white #blood cells (#monocytes) to reduce #innate #immune functions and how it evades the mucus layer in our #nose. 🧵1/
Part 2 looks at how mild and moderate #COVID infection reprograms white #blood cells (#monocytes) to reduce #innate #immune functions and how it evades the mucus layer in our #nose. 🧵1/
An unrolled one-page web view for both parts of this long thread that may be easier to read or share can be found here ( ). 2/
If you haven't read part 1 yet on how the virus hides from T-cells and NK immune cells you can find it here: 3/
How #COVID actively suppresses and evades your immune system [Part 1]
This thread highlights multiple methods that the virus uses to help keep reinfecting people including MHC-I and interferon suppression, evasion of Natural Killer (NK) cells, and reprogramming of monocytes.🧵1/
This thread highlights multiple methods that the virus uses to help keep reinfecting people including MHC-I and interferon suppression, evasion of Natural Killer (NK) cells, and reprogramming of monocytes.🧵1/
An unrolled one-page web view for this long thread that may be easier to read or share can be found here ( ). 2/
COVID has been doing this to varying degrees since the beginning which further reinforces that a vaccine only policy is not enough to stop the cycle of sickness, long term disability, and death. 3/
#Monocytes at the Center of #SARS2 triggered inflammation & severe #Covid19
#SARS2 can cause acute respiratory distress & death in some patients. Although severe #COVID19 disease is linked to exuberant inflammation, how #SARS2 triggers inflammation is not understood. 1/
#SARS2 can cause acute respiratory distress & death in some patients. Although severe #COVID19 disease is linked to exuberant inflammation, how #SARS2 triggers inflammation is not understood. 1/
Monocytes & macrophages are the key sentinel cells that sense invasive infection to form inflammasomes that activate inflammatory cascade by secreting caspase-1 and gasdermin D, leading to inflammatory death (pyroptosis) & release of potent inflammatory mediators. 2/
~6% of monocytes in COVID patients are infected w/ SARS2
Monocyte infection depends on uptake of Ab-opsonized virus by FcÎł receptors
SARS2 begins to replicate in monocytes, but infection is aborted & infectious virus is not detected in infected monocyte culture supernatants. 3/
Monocyte infection depends on uptake of Ab-opsonized virus by FcÎł receptors
SARS2 begins to replicate in monocytes, but infection is aborted & infectious virus is not detected in infected monocyte culture supernatants. 3/
Daily Bookmarks to GAVNet 12/28/2021 greeneracresvaluenetwork.wordpress.com/2021/12/28/dai…
Tissues, not blood, are where immune cells function
nature.com/articles/d4158…
#ImmuneSystem, #COVID19, #ImmuneCells, #cytokines, #TCells, #TissueSamples, #BloodSamples, #monocytes
nature.com/articles/d4158…
#ImmuneSystem, #COVID19, #ImmuneCells, #cytokines, #TCells, #TissueSamples, #BloodSamples, #monocytes
Science fiction revisited: Ramjet propulsion
phys.org/news/2021-12-s…
#RamjetPropulsion, #PropulsionSystems, #InterstellarTravel, #ScienceFiction
phys.org/news/2021-12-s…
#RamjetPropulsion, #PropulsionSystems, #InterstellarTravel, #ScienceFiction
01/ Vous voulez savoir :
- comment se protéger d’une #COVID sévère sans médicaments sur ordonnance ?
- pourquoi elle touche certaines personnes et pas d'autres ?
- ce qui cause les #EffetsSecondaires des #vaccins ?
#COVID_19 #covid19 #covid #coronavirus #vaccination
↓↓↓↓↓
- comment se protéger d’une #COVID sévère sans médicaments sur ordonnance ?
- pourquoi elle touche certaines personnes et pas d'autres ?
- ce qui cause les #EffetsSecondaires des #vaccins ?
#COVID_19 #covid19 #covid #coronavirus #vaccination
↓↓↓↓↓
02/ Jean-Marc Sabatier (@SabatierJeanMa1), Directeur de Recherche au CNRS depuis 32 ans, PhD/HDR en Biochimie et Microbiologie, nous explique tout cela dans une vidéo (crowdbunker.com/v/Mqr69rxT) dont je résume les 42 premières minutes dans ce #thread.
03/ Le virus #SARS-CoV-2 s’attaque au #SRA (le système rénine-angiotensine), un de nos systèmes de régulation les plus importants, responsable des fonctions autonomes rénales, pulmonaires, cardiovasculaires, de l’#immunité innée et du #microbiote intestinal.
