Discover and read the best of Twitter Threads about #Klebsiella

Most recents (4)

#idboardreview 80 M originally from Philippines w/ yearly travel there, presents w/ fever, abd pain, chills, inc LFTs, +liver abscess. BC+ organism? #meded #idmeded #idtwitter
hypervirulent #klebsiella pneumoniae liver abscess Ref academic.oup.com/ofid/article/7…
Infections with #hypervirulent #Klebsiella pneumoniae isolates most frequently occur among pts with an Asian, Pacific Islander, or Hispanic ethnic background, even in absence of travel to high-prevalence areas (eg, Asian Pacific Rim). Diabetes is also a risk factor
Read 5 tweets
Images of Infectious Diseases

2 months after visiting family and friends in Manila:

39M. No PMH. One week of fever, chills, cough, pleuritic chest pain, RUQ pain.

Now complains of blurred vision due to endophthalmitis.

Your DDx? #MayoIDQ and case details to follow… Image
2/
39M. No PMH. HIV-. No IDU.
PE: jaundice, endophthalmitis, no dental issues, b/l rales, new systolic murmur, tender RUQ
WBC 18.3 Alk phos 250.
CT chest / abdomen (photo)
TEE: mitral valve vegetation
Which of the following is the most likely pathogen? #MayoIDQ
3/
Let us use this case to highlight clinical pearls about liver abscess:

Two major categories
1. Pyogenic liver abscess
2. Amoebic liver abscess

In this case, there are factors that favor pyogenic liver abscess: endocarditis, septic pulmonary emboli and endophthalmitis
Read 9 tweets
A series of images presented by an ID fellow to a faculty panel in the “Challenging Cases” session of the #MayoIDFellowsForum

The fellow asked the experts: What diagnosis comes to mind?

#IDTwitter, what do you think?
Clinical details, #MayoIDQ and MCQ to follow...
2/
Awesome list of potential pathogens... from staphylococcus / streptococcus to nocardia, TB, fungi (Mucor, Candida, endemics) and toxoplasma, and others.

Without knowing the host and scenario, all are possible. Thank you #IDTwitter.
Now let us learn about the case details..
3/
45M found unconscious.
PMH: alcohol use disorder. No IDU.
PE: T103F RR32 PR110
Meningismus.
Murmur. Rales.
No skin lesions.
WBC 27K.
Imaging (photo). No PFO.
CSF TNC 9450 /N92% /prot 150 / glu 20

Name the pathogen.
Read 16 tweets
I learned of a new #Klebsiella species today! K. huaxiensis, described in biorxiv.org/content/early/…

Here it is in a tree with the rest of Klebsiella/Raoultella: Image
In case anyone's curious, this is a neighbour-joining (BIONJ) tree made from FastANI distances between whole genome assemblies.
I've also added it to the Kleborate species database, so it can now identify K. huaxiensis assemblies.
github.com/katholt/Klebor…
Read 3 tweets

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