Discover and read the best of Twitter Threads about #Kidneywk
Most recents (24)
1/ Want to continue the learning streak of #Kidneywk ?
#MedTwitter #NephTwitter, we bring another #ASPNFOAM group tweetorial based on pathology webinar @ASPNeph on T-cell mediated rejection(TCMR) in kidney transplant (Tx)
#MedTwitter #NephTwitter, we bring another #ASPNFOAM group tweetorial based on pathology webinar @ASPNeph on T-cell mediated rejection(TCMR) in kidney transplant (Tx)
2/
Let's start with a vignette! 13 yr M with CAKUT s/p DDKT 6mo ago, p/w with doubling of Cr from 0.7 to 1.5 mg/dl, normal vitals and PE. UA normal. A lot of recent stressors and concern for non-adherence.
Sounds like a familiar scenario?
Let's start with a vignette! 13 yr M with CAKUT s/p DDKT 6mo ago, p/w with doubling of Cr from 0.7 to 1.5 mg/dl, normal vitals and PE. UA normal. A lot of recent stressors and concern for non-adherence.
Sounds like a familiar scenario?
What is the potential cause of graft dysfunction in this patient?
Different mechanisms related to Cyrstal Induced Kidney Damage
#CystalDamage #AKI #KidneyWk @ASNKidney
#CystalDamage #AKI #KidneyWk @ASNKidney
Sulfadiazine, Acyclovir, Methothrexate, Ataxanavir clinical vignettes of #CystalDamage #AKI #KidneyWk @ASNKidney
Summary of some medications causing crystalline nephropathies. #CystalDamage #AKI #KidneyWk @ASNKidney
#DrugToxicity a focus on mithocondrial damage. Consider different factors related to drug toxicity.
#KidneyWk @ASNKidney
#KidneyWk @ASNKidney
Proximal Convoluted Tubule involved in toxicity due to hi density of mitochondria #DrugToxicity #KidneyWk @ASNKidney
Plenary #3 at @ASNKidney #KidneyWk on Wearable Devices for Fluid Management: nanomaterials for #KidneyHealth - Silicon integrated circuits
Devices mounted in the human body at different sites to monitor health status: different capabilities, minimally invasive (i.e. neonatal)
#WearableDevices #KidneyWk @ASNKidney
#WearableDevices #KidneyWk @ASNKidney
Mechanical Circulatory Support Devices and the Kidney beyond Cardiogenic Shock (high incidence of AKI) #CirculatoryDevices
#KidneyWk @ASNKidney
#KidneyWk @ASNKidney
Intravascular Devices: IAMP and Impella and their relationship with GFR and/or AKI
#CirculatoryDevices
#KidneyWk @ASNKidney
#CirculatoryDevices
#KidneyWk @ASNKidney
Impact of these intravascular devices on Kidney Function and AKI
#CirculatoryDevices
#KidneyWk @ASNKidney
#CirculatoryDevices
#KidneyWk @ASNKidney
Focus on POCUS in CRS #FluidManagement
First of all understand what is POCUS and how to use it
#KidneyWk @ASNKidney
First of all understand what is POCUS and how to use it
#KidneyWk @ASNKidney
Focused Clinical Questions in #AKI. Which are our regular tools and how they perform? @NephroP
#POCUS #KidneyWk @ASNKidney
#POCUS #KidneyWk @ASNKidney
Physical Exam in Real Life, Fluid Balance (I&O’s) in real life vs. FoCUS
#POCUS #KidneyWk @ASNKidney
#POCUS #KidneyWk @ASNKidney
A MUST: “mRNA as a medicine” Melissa Moore, MD leads us through drug development, from Penicillin to MABs #KidneyWk @ASNKidney
More than 100 monoclonal antibodies have been approved by @US_FDA but they have multiple limitations #KidneyWk @ASNKidney
Proteins have been used as medicine, but only a small proportion can be used, whereas mRNA enable the body to produce “own medicine” #KidneyWk @ASNKidney
The most anticipated nephrology trial of the year has been published!
“Empagliflozin in Patients with Chronic Kidney Disease” #Kidneywk
@NEJM nejm.org/doi/full/10.10…
“Empagliflozin in Patients with Chronic Kidney Disease” #Kidneywk
@NEJM nejm.org/doi/full/10.10…
EMPA-KIDNEY trial is a randomized, parallel-group, double-blind, placebo-controlled trial designed to assess the effect of empagliflozin on progression of kidney disease & CV disease, & to examine safety profile of the drug in a wide range of pts. w/ CKD
The trial included patients without diabetes, patients with an eGFR of less than 30 ml per minute per 1.73 m2, and patients with low levels of proteinuria
People are living in crisis from hunger 🚨 @USDA est that 30 mil in USA (includ 12 mil children) are experiencing food insecurity.
Many Americans are just a job loss, missed paycheck, or 🏥 medical emergency away from experiencing hunger.
#HCWvsHunger 🍎 #UrineItToWinIt 🍏
🧵1/
Many Americans are just a job loss, missed paycheck, or 🏥 medical emergency away from experiencing hunger.
#HCWvsHunger 🍎 #UrineItToWinIt 🍏
🧵1/
Food insecurity (FI) is lack of *consistent & socially acceptable* access to enough safe food for an active, healthy life. The COVID-19 pandemic has exacerbated FI for so many.
#HCWvsHunger 🍎 #UrineItToWinIt 🍏
2/
#HCWvsHunger 🍎 #UrineItToWinIt 🍏
2/
Why should FI matter to #NephTwitter? It’s a social determinant of health w/ *major* implications 👉 poorer overall levels of health, chronic med conditions, & lower levels of psychosocial/physical functioning.
renalfellow.org/2018/02/13/hun…
@mcstarr1 @RenalFellowNtwk
#HCWvsHunger
3/
renalfellow.org/2018/02/13/hun…
@mcstarr1 @RenalFellowNtwk
#HCWvsHunger
3/
/the information dilemma_
A 17-tweet summary of my academic contribution to the #KidneyWk 2021 meeting.
@ASNKidney: Thanks for selecting my work for presentation...I appreciate it.
A 17-tweet summary of my academic contribution to the #KidneyWk 2021 meeting.
@ASNKidney: Thanks for selecting my work for presentation...I appreciate it.
2
My disclosures
I am a physician-programmer. I analyze #SoMe data, with a keen focus on Twitter. I primarily analyze tweets in #NephTwitter and #CardioTwitter, and I have analyzed tweets for Oncology and Endocrinology organizations as well.
My disclosures
I am a physician-programmer. I analyze #SoMe data, with a keen focus on Twitter. I primarily analyze tweets in #NephTwitter and #CardioTwitter, and I have analyzed tweets for Oncology and Endocrinology organizations as well.
3
We face an information dilemma we face in medical communities. The dilemma originates from customized search results. How can anything customized *to/for you* be a negative?
It's negative when ≥2 people are searching for the same thing (the truth) & getting different results.
We face an information dilemma we face in medical communities. The dilemma originates from customized search results. How can anything customized *to/for you* be a negative?
It's negative when ≥2 people are searching for the same thing (the truth) & getting different results.
Polarization in #KidneyWk Educational Community by Avrum Gillespie @AvrumGillespie
The agenda #KidneyWk
Why we tweet. #KidneyWk
Michelle Lim @whatsthegfr on Visual Abstracts. She runs the NSMC Graphical Communication Rotation. No one, even @AndrewMIbrahim himself (sorry), would be a better speaker for this talk. Great get by @ASNKidney #KidneyWk
History of the Visual Abstract #KidneyWk Check the QR code
Challenges
Busy clinical services, balance, sub-specialization, research demands, business getting complex. #KidneyWk
Busy clinical services, balance, sub-specialization, research demands, business getting complex. #KidneyWk
Getting to the goal! #KidneyWk
Mineralocorticoid receptor (MR) has a role in:
👉 BP regulation
👉 Electrolyte Homeostasis
Overactivation of MR leads to:
👉 Inflammation and Fibrosis
👉 Sodium retention
#KidneyWk #Nephpearls #Cardiorenal
👉 BP regulation
👉 Electrolyte Homeostasis
Overactivation of MR leads to:
👉 Inflammation and Fibrosis
👉 Sodium retention
#KidneyWk #Nephpearls #Cardiorenal
Finerenone: potent and selective non-steroidal MR antagonist (MRA) that is distinct from steroidal MRAs
#KidneyWk #Nephpearls #Cardiorenal
#KidneyWk #Nephpearls #Cardiorenal
FIDELITY pre-specified pooled analysis
👉 FIDELIO-DKD
👉 FIGARO-DKD
#KidneyWk #Nephpearls #Cardiorenal
👉 FIDELIO-DKD
👉 FIGARO-DKD
#KidneyWk #Nephpearls #Cardiorenal
High Impact Clinical Trials
TESTING Study: Steroids vs. Placebo in High Risk IgAN @VladoPerkovic
💥Conclusion: A 6-9 month course of oral methylprednisolone reduced risk of major kidney outcomes by 47% and kidney failure by 41%
#KidneyWk
TESTING Study: Steroids vs. Placebo in High Risk IgAN @VladoPerkovic
💥Conclusion: A 6-9 month course of oral methylprednisolone reduced risk of major kidney outcomes by 47% and kidney failure by 41%
#KidneyWk
TESTING Study - Basline Characteristics
Effect on primary outcome based on full and reduced Steroid dose
Happening now at #RPA21:
The Challenges of Social Media Education: A data-driven specialty-specific introspection
rpa2021.onlineeventpro.freeman.com/live-stream/19…
I'm live on the RPA platform and Twitter for your questions
The Challenges of Social Media Education: A data-driven specialty-specific introspection
rpa2021.onlineeventpro.freeman.com/live-stream/19…
I'm live on the RPA platform and Twitter for your questions
1/#rpa21
My disclosures
I created Nephrology On-Demand in 2010
I launched @NODanalytics in 2015
I made @NODanalytics free for educational use in 2018
I created NephTwitterArchive.com to mitigate the perils of customized search
goo.gl/mfziXG
My disclosures
I created Nephrology On-Demand in 2010
I launched @NODanalytics in 2015
I made @NODanalytics free for educational use in 2018
I created NephTwitterArchive.com to mitigate the perils of customized search
goo.gl/mfziXG
2/#rpa21
Many specialties are gravitating to Twitter for education & learning.
Some are more advanced than others; it is very evident that #NephTwitter is far more advanced than other specialties: longer experience w/#SoMe education & more offerings.
Many specialties are gravitating to Twitter for education & learning.
Some are more advanced than others; it is very evident that #NephTwitter is far more advanced than other specialties: longer experience w/#SoMe education & more offerings.
💥”Adverse Effects of SGLT2”
- amazing talk by @jardine_meg
#KidneyWk @ASNKidney
⚡️SGLT2i adverse events data from the major SGLT2i trials including the CV outcomes trials, Heart failure trials, CREDENCE trial and DAPA-CKD Trial
- amazing talk by @jardine_meg
#KidneyWk @ASNKidney
⚡️SGLT2i adverse events data from the major SGLT2i trials including the CV outcomes trials, Heart failure trials, CREDENCE trial and DAPA-CKD Trial
⚡️Overall the serious adverse events associated with SGLT2i use were lower than the adverse events seen with placebo use in most of the large SGLT2i trials👇🏽
⚡️SGLT2i associated adverse events were similar across the eGFR spectrum meaning that low eGFR was not associated with higher risk of adverse events compared to high eGFR - as seen in the CREDENCE trial👇🏽
A summary of our oral abstract at #kidneywk. Prelim outcomes utilizing both Ellipsys and WavelinQ for #endoavf creations. Compiled and presented by Dr. Genena, one of our fellows. 1/x @ASDINNews #NephTwitter
Let’s be clear. This isn’t intended as a direct device comparison. This isn’t about if one device is “better.”
These are a compilation of my experiences, thoughts, opinions and limited to my hands only. Yours may be different. That’s ok. Probably preferred. Share and learn. 2/x
These are a compilation of my experiences, thoughts, opinions and limited to my hands only. Yours may be different. That’s ok. Probably preferred. Share and learn. 2/x
It is more of a comparison between the endo-anastomoses. I hypothesized outcomes would be discerned by the location of the anast, so that’s how they are divided and grouped.
Ellipsys: prox RA - perforating vein anast
WavelinQ Ulnar: UA - UV
WavelinQ Radial: prox RA - RV 3/x
Ellipsys: prox RA - perforating vein anast
WavelinQ Ulnar: UA - UV
WavelinQ Radial: prox RA - RV 3/x
💥COVID-19 in Dialysis Patients
@ASNKidney #KidneyWk #COVID19
⚡️Limiting Spread of Infection in the HD unit by @KidneySW
Some key pearls 💎
⚡️The 1st patient to die due to COVID-19 in the United States was a Hemodialysis patient (died on 28th Feb, 2020)
@ASNKidney #KidneyWk #COVID19
⚡️Limiting Spread of Infection in the HD unit by @KidneySW
Some key pearls 💎
⚡️The 1st patient to die due to COVID-19 in the United States was a Hemodialysis patient (died on 28th Feb, 2020)
⚡️How contagious is SARS-CoV-2 virus?
⚡️More contagious than Influenza but less contagious than Measles
⚡️Each SARS-CoV-2 positive person can infect 3 more people👇🏽
⚡️More contagious than Influenza but less contagious than Measles
⚡️Each SARS-CoV-2 positive person can infect 3 more people👇🏽
⚡️ESKD patients are 5x more likely to have COVID-19 than other Medicare beneficiaries
⚡️ESKD patients are 8x more likely to be hospitalized due to COVID-19 than other Medicare beneficiaries👇🏽
⚡️ESKD patients are 8x more likely to be hospitalized due to COVID-19 than other Medicare beneficiaries👇🏽
Continuing our #KidneyWk virtual e-poster tour! Check out this thread for some interesting research on #exercise, #PhysicalActivity, & #PhysicalFunction in CKD and ESKD!
A comparison of #frailty measures among individuals referred for #KidneyTransplant in Canada (PO1704). #KidneyWk @FilteredDoc @tennankore @CNTN_RCEN
A pilot RCT to embed technology-enabled group-based #Exercise programming in the clinic: The Exercise Is Medicine in Chronic Kidney Disease Trial (PO2057). #KidneyWk @felipelobelo @ahadbootwala @Shuchi_Anand @JasonCobbMD
Fluid overload is bad news for patients:
1. Causes AKI
2. Prevents organ and patient recovery
3. Increases mortality
Ill share some of the data masterfully presented by @criticalbeansmd today at #KidneyWk starting with the take home points, in case this is the only tweet you see
1. Causes AKI
2. Prevents organ and patient recovery
3. Increases mortality
Ill share some of the data masterfully presented by @criticalbeansmd today at #KidneyWk starting with the take home points, in case this is the only tweet you see
Fluid Overload is very common, is all over the place and it has several definitios.
Patients accumulate weight at least for the first 7 days if the ICU doesn’t have some sort of FLUID STEWARDSHIP program in place. Remember fluids are drugs #KidneyWk.
Patients accumulate weight at least for the first 7 days if the ICU doesn’t have some sort of FLUID STEWARDSHIP program in place. Remember fluids are drugs #KidneyWk.
There is no single situation in which Fluid overload is beneficial for patients. On the contrary. It is bad in every situation, doesnt matter how we slice or present the data. Liberal fluid strategies are always worse #KidneyWk
All nephrologists should be learning #POCUS now. It is safe, reproducible, cheap!!! Some uses are:
1. Rule out obstruction
2. Dx cause of hemodynamic inestability
3. To guide vascular access
@WBeaubien #KidneyWk
1. Rule out obstruction
2. Dx cause of hemodynamic inestability
3. To guide vascular access
@WBeaubien #KidneyWk
Beyon the basic applications in #AKI
1. Assessment of kidney perfussion
2. Detection of early AKI
3. Prediction ofpersistent AKI
4. Detect kidney congestion
2D US is ok, but using other modalities like doppler we can get more granular data on kidney hemodynamics.
#kidneywk
1. Assessment of kidney perfussion
2. Detection of early AKI
3. Prediction ofpersistent AKI
4. Detect kidney congestion
2D US is ok, but using other modalities like doppler we can get more granular data on kidney hemodynamics.
#kidneywk
However using only color doppler or power doppler is not good enough. #KidneyWk
