Discover and read the best of Twitter Threads about #IDBR
Most recents (7)
#MayoIDFellowship Core Curriculum Lecture series
Dr. Wengenack asked our fellows to identify this fungi with “spaghetti and meatballs” appearance. #IDBR #MayoIDQ
Dr. Wengenack asked our fellows to identify this fungi with “spaghetti and meatballs” appearance. #IDBR #MayoIDQ
#Malassezia
Microbiologists identify #Malassezia as the “spaghetti and meatball” yeast that causes the prototypical recurrent skin disease, tinea / pityriasis versicolor, characterized by hypo/hyperpigmented plaques and scales, often seen over the back, chest, and neck.
Microbiologists identify #Malassezia as the “spaghetti and meatball” yeast that causes the prototypical recurrent skin disease, tinea / pityriasis versicolor, characterized by hypo/hyperpigmented plaques and scales, often seen over the back, chest, and neck.
#Malassezia species are obligatory lipophilic and requires oil for growth.
BONUS point!
#MicroBoardReview
Name the major zoophilic species of Malassezia that does NOT require lipids for growth.
BONUS point!
#MicroBoardReview
Name the major zoophilic species of Malassezia that does NOT require lipids for growth.
Weekend Digest
Name the Pathogen
5 Clues:
- #Chitlins
- #Iron sepsis
- Mesenteric #adenitis
- Reactive #arthritis
- Terminal #ileitis
Name the Pathogen
5 Clues:
- #Chitlins
- #Iron sepsis
- Mesenteric #adenitis
- Reactive #arthritis
- Terminal #ileitis
2/
#Yersinia enterocolitica
It is #zoonotic and is acquired by exposure to contaminated food.
When #IDBR says #chitlins (#chitterlings), you say Y. enterocolitica
Chitlins are food made of pork intestines (where Y enterocolitica resides)
ncbi.nlm.nih.gov/pmc/articles/P…
#Yersinia enterocolitica
It is #zoonotic and is acquired by exposure to contaminated food.
When #IDBR says #chitlins (#chitterlings), you say Y. enterocolitica
Chitlins are food made of pork intestines (where Y enterocolitica resides)
ncbi.nlm.nih.gov/pmc/articles/P…
3/
#Yersinia enterocolitica
Enterobacteriaceae #GNB that causes #enterocolitis, diarrhea (often bloody), terminal #ileitis, mesenteric #adenitis, and RLQ pain that may be mistaken as #appendicitis (#pseudoappendicitis)
#Yersinia enterocolitica
Enterobacteriaceae #GNB that causes #enterocolitis, diarrhea (often bloody), terminal #ileitis, mesenteric #adenitis, and RLQ pain that may be mistaken as #appendicitis (#pseudoappendicitis)
Weekend Digest
Name the pathogen
5 clues
GNB with musty odor
Clenched fist injury
Culture negative endocarditis
Needle licker osteomyelitis
Toothpick septic arthritis
Name the pathogen
5 clues
GNB with musty odor
Clenched fist injury
Culture negative endocarditis
Needle licker osteomyelitis
Toothpick septic arthritis
2/
#Eikenella corrodens
Part of human oral flora
Component of polymicrobial infection related to human bites.
#IDBR buzzword is clenched-fist injury – when it is inoculated to injured knuckle of a clenched fist that strikes teeth of an opponent.
doi.org/10.1016/S0363-…
#Eikenella corrodens
Part of human oral flora
Component of polymicrobial infection related to human bites.
#IDBR buzzword is clenched-fist injury – when it is inoculated to injured knuckle of a clenched fist that strikes teeth of an opponent.
doi.org/10.1016/S0363-…
3/
#Eikenella corrodens is the “E” in HACEK – agents of culture negative endocarditis
HACEK organisms can now be cultured with current culture techniques, hence they should no longer be called “culture negative” pathogens!
#Eikenella corrodens is the “E” in HACEK – agents of culture negative endocarditis
HACEK organisms can now be cultured with current culture techniques, hence they should no longer be called “culture negative” pathogens!
Weekend Digest
Name the pathogen.
Pain and discomfort when you pee
But Hans Christian Gram cannot see
Try to kill me with Doxy
Moxi chaser sets you symptom-free.
Name the pathogen.
Pain and discomfort when you pee
But Hans Christian Gram cannot see
Try to kill me with Doxy
Moxi chaser sets you symptom-free.
2/
#Mycoplasma #genitalium
“Cause of #NGU not visible by Gram stain and treated with two-stage approach using #doxycycline followed by #moxifloxacin chaser!”
Fellows, this is #IDBR material, definitely!
#Mycoplasma #genitalium
“Cause of #NGU not visible by Gram stain and treated with two-stage approach using #doxycycline followed by #moxifloxacin chaser!”
Fellows, this is #IDBR material, definitely!
3/
#Mycoplasma #genitalium
Diseases;
Men: persistent / recurrent non-gonococcal urethritis (NGU) / non-chlamydia urethritis
Women: cervicitis, PID, preterm delivery, spontaneous abortion, infertility
Many infections are asymptomatic!
Don’t forget: rectal / pharyngeal infection
#Mycoplasma #genitalium
Diseases;
Men: persistent / recurrent non-gonococcal urethritis (NGU) / non-chlamydia urethritis
Women: cervicitis, PID, preterm delivery, spontaneous abortion, infertility
Many infections are asymptomatic!
Don’t forget: rectal / pharyngeal infection
#MayoIDQ #IDBR
45M CC: tender mass on left thigh that started as an “insect bite” 4 days ago. No F/C. PE: tender fluctuant 2-cm mass with surrounding erythema.
After I&D of abscess in the clinic, what do you recommend?
45M CC: tender mass on left thigh that started as an “insect bite” 4 days ago. No F/C. PE: tender fluctuant 2-cm mass with surrounding erythema.
After I&D of abscess in the clinic, what do you recommend?
2/
2014 IDSA guideline recommends incision and drainage of purulent SSTI (abscess)
Antibiotics vs MRSA / S. aureus as an adjunct to I&D if:
1. SIRS
2. Failed initial Ab Rx
3. Impaired host defense
Any new data since then?
doi.org/10.1093/cid/ci…
2014 IDSA guideline recommends incision and drainage of purulent SSTI (abscess)
Antibiotics vs MRSA / S. aureus as an adjunct to I&D if:
1. SIRS
2. Failed initial Ab Rx
3. Impaired host defense
Any new data since then?
doi.org/10.1093/cid/ci…
3/
After 2014 IDSA guideline, placebo-controlled RCTs were published on use of antibiotics (TMP SMX or clindamycin) for uncomplicated SSTI abscess ... (next)
ncbi.nlm.nih.gov/pmc/articles/P…
After 2014 IDSA guideline, placebo-controlled RCTs were published on use of antibiotics (TMP SMX or clindamycin) for uncomplicated SSTI abscess ... (next)
ncbi.nlm.nih.gov/pmc/articles/P…
Weekend Digest
Name the pathogen!
H & E stain of heart tissue of a 27M who developed severe intractable heart failure 2 months after an allogeneic bone marrow transplant for acute leukemia.
Clue: consumption of food / water contaminated with feces of snakes
Name the pathogen!
H & E stain of heart tissue of a 27M who developed severe intractable heart failure 2 months after an allogeneic bone marrow transplant for acute leukemia.
Clue: consumption of food / water contaminated with feces of snakes
2/
#Sarcocystosis
1. Sarcocystis hominis, suihominis, nesbetti, others
2. Zoonotic: 2 forms for human infection
3. Intestinal and muscular sarcosystosis
4. Dx: intestinal (O/P), muscular (biopsy)
5. Rx: not well defined; TMP-SMX, albendazole, others
cmr.asm.org/content/28/2/2…
#Sarcocystosis
1. Sarcocystis hominis, suihominis, nesbetti, others
2. Zoonotic: 2 forms for human infection
3. Intestinal and muscular sarcosystosis
4. Dx: intestinal (O/P), muscular (biopsy)
5. Rx: not well defined; TMP-SMX, albendazole, others
cmr.asm.org/content/28/2/2…
3/
Intestinal #Sarcocystosis
1. Ingestion of sarcocyst (S. hominis / beef, suihominis / pork) in tissue
2. Sarcocyst digested —> bradyzoites —> intestinal infection / gametes —> oocysts / sporocyst detected in stool
3. Self limited. No Rx needed
cmr.asm.org/content/28/2/2…
Intestinal #Sarcocystosis
1. Ingestion of sarcocyst (S. hominis / beef, suihominis / pork) in tissue
2. Sarcocyst digested —> bradyzoites —> intestinal infection / gametes —> oocysts / sporocyst detected in stool
3. Self limited. No Rx needed
cmr.asm.org/content/28/2/2…
70M with swollen R 5th digit, hand and forearm. No fever / chills.
MRI: complex multi-compartment fluid collection with extensive flexor and extensor tenosynovitis
Debridement. Culture (photo).
What is your diagnosis and Rx?
#MayoIDQ MCQ to follow...
MRI: complex multi-compartment fluid collection with extensive flexor and extensor tenosynovitis
Debridement. Culture (photo).
What is your diagnosis and Rx?
#MayoIDQ MCQ to follow...
Elderly man with swollen right hand and forearm. MRI: complex fluid collection, extensive tenosynovitis. Debridement performed. Culture is shown (photo prior tweet).
Which of the following is the exposure associated with this infection?
Which of the following is the exposure associated with this infection?
3/
Beaver dam and blastomyces
When #IDBR says #beaverdam - you think #BLASTOMYCOSIS
nejm.org/doi/10.1056/NE…
Beaver dam and blastomyces
When #IDBR says #beaverdam - you think #BLASTOMYCOSIS
nejm.org/doi/10.1056/NE…
