Discover and read the best of Twitter Threads about #HOCM
Most recents (4)
1a) Welcome to a new #accredited #tweetorial, “MOA and Clinical Trial Data for Novel & Emerging Therapeutic Strategies for #HCM: Can We Target Our Therapy?" 
1b) Our expert (and returning @cardiomet_ce) author is Giuseppe Galati MD, MMSc in Heart Failure, FHFA, @GiuseppeGalati_ , Consultant #Cardiologist #HeartFailure & #Cardiomyopathies
2) @GiuseppeGalati_ is in Milan 🇮🇹 This program is intended for #healthcare professionals & is accredited for 0.75h CE/#CME credit for #physicians #physicianassistants #nurses #nursepractitioners #pharmacists.
1) Welcome to a new #accredited #tweetorial on #hypertrophic #cardiomyopathy #HCM. Our expert author is Ahmad Masri MD @MasriAhmadMD of @OHSUCardio where he leads the Hypertrophic Cardiomyopathy Ctr. See a previous program from him, on #Fabry disease, at cardiometabolic-ce.com/cardiorenal-fa….
2a) This program is intended for #healthcare providers and is supported by an educational grant from Bristol-Myers Squibb. Statement of accreditation and faculty disclosures at cardiometabolic-ce.com/disclosures/. FOLLOW US for the most timely expert education in #cardiometabolic care!
2b) #Physicians #Nurses #PhysicianAssociates #NursePractitioners #Pharmacists earn a full 1⃣ hour of 🆓CE/#CME credit from following this 🧵. For educational purposes, Twitter still works!! 😁
Very interesting results from Phase 3 #EXPLORER-HCM clinical trial: #mavacamten vs placebo for symptomatic #HOCM at #ESCCongress2020 . A new tool is given consideration for patients with obstructive HCM. The authors have to be congratulated. Excellent presentation by I. Olivotto
Is this the beginning of a dream in the treatment of HCM? Will it challenge and replace invasive septal reduction therapies by achieving sustained resolution of obstruction, complete symptom relief, neutralize risk of SCD without side effects? Let's deep into the study
The primary endpoint involved NYHA and VO2 consumption. The definition of responders requires minimal changes in objective exercise capacity and a drop of only one class. Despite this, only 20% of treated patients fulfilled it at 30 weeks
Hypertrophic Obstructive Cardiomyopathy #HOCM🚧
#Symptoms
Profound exertional dyspnea
#Imaging
▪️SAM/LVOT obstruction #whyCMR
▪️Classic #Doppler🗡#echofirst
#Hemodynamics
▪️Brockenbrough-Braunwald-Morrow sign, explained
#Treatment
▪️Alcohol🍷septal ablation #RadialFirst
#Symptoms
Profound exertional dyspnea
#Imaging
▪️SAM/LVOT obstruction #whyCMR
▪️Classic #Doppler🗡#echofirst
#Hemodynamics
▪️Brockenbrough-Braunwald-Morrow sign, explained
#Treatment
▪️Alcohol🍷septal ablation #RadialFirst
🙏 @hopkinsheart @JonResar @RaniKHasan @kman8585 @DoctorLatina for unlocking these concepts for me!
@PushpaShivaram @AnastasiaSMihai @HeartOTXHeartMD
@DavidWienerMD @DrJayMohan @DxRxEdu @MasriAhmadMD @onco_cardiology @NadeenFaza @dr_chirumamilla @mirvatalasnag @TheVeggieMD
@PushpaShivaram @AnastasiaSMihai @HeartOTXHeartMD
@DavidWienerMD @DrJayMohan @DxRxEdu @MasriAhmadMD @onco_cardiology @NadeenFaza @dr_chirumamilla @mirvatalasnag @TheVeggieMD
Question:
Why wouldn’t more filling time⏱ prior to post PVC beat lead to less obstruction, less gradient, & ↑ arterial pressure?
After all, doesn’t ↑LV volume in #HCM ↓gradient and improve symptoms?
Cornerstone tx is hydration/💊s that ↑ diastolic filling time ...
Why wouldn’t more filling time⏱ prior to post PVC beat lead to less obstruction, less gradient, & ↑ arterial pressure?
After all, doesn’t ↑LV volume in #HCM ↓gradient and improve symptoms?
Cornerstone tx is hydration/💊s that ↑ diastolic filling time ...
