Discover and read the best of Twitter Threads about #ESCCongress2020

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Very interesting results from Phase 3 #EXPLORER-HCM clinical trial: #mavacamten vs placebo for symptomatic #HOCM at #ESCCongress2020 . A new tool is given consideration for patients with obstructive HCM. The authors have to be congratulated. Excellent presentation by I. Olivotto
Is this the beginning of a dream in the treatment of HCM? Will it challenge and replace invasive septal reduction therapies by achieving sustained resolution of obstruction, complete symptom relief, neutralize risk of SCD without side effects? Let's deep into the study
The primary endpoint involved NYHA and VO2 consumption. The definition of responders requires minimal changes in objective exercise capacity and a drop of only one class. Despite this, only 20% of treated patients fulfilled it at 30 weeks
Read 12 tweets
Happy #VivienThomasDay! Today marks 110 years since the birth of Dr. Vivien Thomas. Although he never went to medical school, the surgical techniques he developed, such as the BTT shunt, are the foundation on which congenital heart surgery today was built. #CHD #ESCCongress2020
After graduating from high school, Thomas enrolled at Tennessee Agricultural & Industrial State College (now @TSUedu) as a pre-med. Unfortunately, the Great Depression depleted his savings, so he left college and found work as an assistant in Alfred Blalock's lab at @VUmedicine.
Blalock was doing research in traumatic shock and needed Thomas to help perform surgery on lab animals. Thomas learned quickly, and Blalock gave him more and more independence in the lab. Years later, surgical trainees who worked with Thomas would marvel at his surgical skill.
Read 10 tweets

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