Discover and read the best of Twitter Threads about #GeneExpression

Most recents (8)

Finally published! 🎉 reposting d/t broken link in first thread:

Early-life exercise primes the murine neural epigenome to facilitate gene expression and hippocampal memory consolidation | Communications Biology nature.com/articles/s4200…
Our study discovers both new and well-known #geneexpression programs involved in #hippocampal memory following #adolescent #exercise, and also investigates two #epigenetic modifications in these mechanisms (open access @CommsBio)
We asked which genes are altered following aerobic exercise (voluntary wheel running) in adolescent hippocampus, using a transgenic mouse & technique we developed for simultaneous sequencing of the epigenome and translatome in excitatory neurons.
Read 8 tweets
It’s here! 🎉 Our study reveals both new and known #geneexpression programs involved in hippocampal memory following #adolescent #exercise, and also investigates two #epigenetic regulatory mechanisms (open access @CommsBio) 1/

urldefense.com/v3/__https://r…$
We asked which genes are regulated after aerobic exercise (voluntary wheel running) in adolescent #hippocampus using a transgenic mouse & technique we developed for simultaneous sequencing of the #epigenome and translatome in excitatory #neurons. 2/
Using our “SIT”protocol from a single hippocampus (Simultaneous INTACT and TRAP; yes we used “SIT” in running mice!) found high correlation (Spearman’s) when compared to traditional INTACT/TRAP in separate samples. Protocol here: 3/

…rentprotocols.onlinelibrary.wiley.com/doi/full/10.10…
Read 9 tweets
Enamorarse hace que las células del sistema inmunitario se comporten diferente 💘🧬

Un grupo interdisciplinario de investigación en Estados Unidos reportó que algunos genes aumentan su expresión y otros la disminuyen cuando hay un enamoramiento 😍

Les cuento🧵👇🏼

1/12
Primero un pequeño recordatorio sobre la expresión génica:

Los seres vivos guardamos la información para construir todas nuestras proteínas en nuestro material genético, el #ADN🧬. El cual está dividido en secciones llamadas genes

2/12

#GeneExpression #Biology
Para que la información de un #gen se traduzca en la producción de una proteína es necesario que primero se transcriban las instrucciones en una molécula de #RNA mensajero (#mRNA) que la célula pueda leer

A la producción de ese mRNA le llamamos expresión génica

Ahora sí..

3/12
Read 13 tweets
Daily Bookmarks to GAVNet 04/12/2021 greeneracresvaluenetwork.wordpress.com/2021/04/12/dai…
The Weekly Quill – The Hope Diamond in the Rough

linkedin.com/pulse/weekly-q…

#history #diamonds #mining
You Might Have Earned It, But Don’t Forget That Your Wealth Came from Society

evonomics.com/wealth-of-huma…

#wealth #SocialInstitutions #value #InformationProcessing #profit #power #responsibility
Read 10 tweets
Please enjoy our new #preprint, "High-throughput discovery and characterization of human transcriptional effectors"! 😀

We tested thousands of protein domains and mutants for the ability to repress/activate #GeneExpression and ID effectors in 600 proteins
biorxiv.org/content/10.110…
For many human #TranscriptionFactors & #chromatin regulators, we know more about *where* they bind than *how* they regulate expression

To find effector domains in an unbiased way, we tested a library of the majority of nuclear protein domains with our new method, HT-recruit Image
We find hundreds of human #repressor domains, including several domains of unknown function Image
Read 13 tweets

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