Discover and read the best of Twitter Threads about #Dopesick
Most recents (11)
Michael Keaton has a reputation for saying no. In fact, he nearly said no to #Dopesick.
bit.ly/3SaoW7c
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The Hulu limited series, based on Beth Macy’s nonfiction book, “Dopesick: Dealers, Doctors, and the Drug Company That Addicted America,” examines the horrifying opioid crisis and its impact.
bit.ly/3SaoW7c
bit.ly/3SaoW7c
#Dopesick was Keaton’s first-ever TV series that he starred in from beginning to end. So, was that a fun process?
“Ish,” he says with a laugh. “At one point I said to Danny, ‘I ain’t ever doing this again.’”
bit.ly/3SaoW7c
“Ish,” he says with a laugh. “At one point I said to Danny, ‘I ain’t ever doing this again.’”
bit.ly/3SaoW7c
Por recomendación de @anavrama me decidí a ver #DOPESICK, aunque tenía ya un par de recomendaciones de peso, de @JC_Anglada y de @enriquemplata. Hago un mini-hilo con algunas reflexiones.
La serie plasma una situación dramática, con unos malos malísimos, encarnados por la industria farmacéutica, que se valen de malaciencia, mentiras y el marketing más agresivo, para hacer de un opioide mayor muy adictivo (oxicodona), un blockbuster.
Estos malos malísimos dejan un rastro de trágicas historias, de muerte y de desgracia, proporcional a sus ganancias. Salvando el componente de ficción de una serie, es evidente que plasma unos acontecimientos de consecuencias reales.
The anxiety-intractable pain feedback mechanism is the worst,
You get anxiety, increases pain, which increases anxiety,
It makes trying to get, well, anything done that much more difficult
You get anxiety, increases pain, which increases anxiety,
It makes trying to get, well, anything done that much more difficult
I don't tend to get writer's block,
I get ideas for writing fine,
it's more a problem of a pain block
If any of you have ideas on how to more easily overcome that difficulty I'd be happy to hear it #chronicpain #writing #WritingCommunity #writingtips #journalism
I get ideas for writing fine,
it's more a problem of a pain block
If any of you have ideas on how to more easily overcome that difficulty I'd be happy to hear it #chronicpain #writing #WritingCommunity #writingtips #journalism
There was a certain scientist I respect that said the priority of pain care is to elevate function,
Which I think is good, but more often than not, pain severely impairs my ability to function & I'm not sure how you delineate the two sides of chronic pain
Which I think is good, but more often than not, pain severely impairs my ability to function & I'm not sure how you delineate the two sides of chronic pain
“Dopesick” is compulsory viewing because in this age of vaccine mandates – when anything short of unabashed adoration of Big Pharma & govt health agencies, as well as compulsive compliance with their edicts, leaves you ostracized from society…”
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rt.com/op-ed/538714-t…
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“Dopesick”…”lays bare the corrosive corruption of capitalism on “science” and exposes egregious government complicity with a pharmaceutical company that directly led to the tragedy of the opioid epidemic.”
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rt.com/op-ed/538714-t…
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“Remarkably, Purdue… got the FDA to allow the company to put a label on OxyContin saying that danger of addiction was extremely low, despite no studies showing this claim to be true. “
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Was watching #Dopesick, and I started reflecting on when I first learned IMS (now IQVIA) tracked every prescription by every doc &sold it to pharma so the doctors could be targeted for drug sales… and how inappropriate that seemed to me. And yet I didn’t do anything.
I was on a plane and a drug representative was sitting beside me going through the prescriptions written by doctors he covered - and there was so much detail. Data-drive marketing…& we docs had no idea the companies were tracking us in this way… & IMS was making billions on it.
It felt like an invasion of privacy… & I was puzzled that it could be legal…we were saying at the time that pharma should not be giving gifts…but we didn’t talk about tracking of individual MD's prescribing patterns by the sales teams - and how they acted on that information.
this is pretty bad, there is nothing said to make clear the deaths are overwhelmingly caused by illicit black-market street quality, FENTANYL
Never made or meant for medical use,
#opioids #news #opioidcrisis #medicine #healthcare #health
Never made or meant for medical use,
#opioids #news #opioidcrisis #medicine #healthcare #health
There's an argument the initial phase of the crisis, 1990s & early 2000s was sparked by prescription opioids,
There's no evidence then or now deaths themselves were caused by anything that ever came in an orange bottle
#healthcare #health #journalism #cnn ncbi.nlm.nih.gov/pmc/articles/P…
There's no evidence then or now deaths themselves were caused by anything that ever came in an orange bottle
#healthcare #health #journalism #cnn ncbi.nlm.nih.gov/pmc/articles/P…
So many things here being conflated here,
Dependence is not addiction
Addiction & overdose deaths are not the same things,
These deaths are mostly accidental including first-time casual users
addiction isn't always the cause of death
reason.com/2021/11/24/sho…
Dependence is not addiction
Addiction & overdose deaths are not the same things,
These deaths are mostly accidental including first-time casual users
addiction isn't always the cause of death
reason.com/2021/11/24/sho…
Speaking to the Economic Roundtable of San Francisco. @CatoHealth #CatoDrugWar
I'm only 10 minutes in but so far so good,
@dr4liberty is always great on the opioid & pain topics
cato.org/multimedia/med… #chronicpain #opioids #opioidcrisis #dopesick
I'm only 10 minutes in but so far so good,
@dr4liberty is always great on the opioid & pain topics
cato.org/multimedia/med… #chronicpain #opioids #opioidcrisis #dopesick
one thing i notice watching his appearances is Dr Singer is always so concise,
always able to pack a ton of important information in just a few short minutes
always able to pack a ton of important information in just a few short minutes
The story at minute 5 about a patient's opioid phobia is pretty good btw,
if you want to jump in that's a good place imo
cato.org/multimedia/med…
if you want to jump in that's a good place imo
cato.org/multimedia/med…
Amazing @MikhailaAleksis Peterson had @slsatel & I talk about the opioid crisis, govs failed response💊
Mass patient abandonment via Opioid Prohibition🤯
#chronicpain #opioidcrisis #Dopesick #DopesickHulu #crime #JordanPeterson #JoeRogan @jordanbpeterson
Mass patient abandonment via Opioid Prohibition🤯
#chronicpain #opioidcrisis #Dopesick #DopesickHulu #crime #JordanPeterson #JoeRogan @jordanbpeterson
In this interview @MikhailaAleksis:
Why are patients being abandoned en mass?
How did the opioid crisis happen?
Why are all efforts by public health failing?
@joerogan @dr4liberty @GhanaboyPharmd @sullydish @bdomenech @wil_da_beast630 @brad_polumbo @LPNH
Why are patients being abandoned en mass?
How did the opioid crisis happen?
Why are all efforts by public health failing?
@joerogan @dr4liberty @GhanaboyPharmd @sullydish @bdomenech @wil_da_beast630 @brad_polumbo @LPNH
We had 100K overdose deaths in 2021,
despite opioid prescriptions being at historic lows
Millions suffering & dying needlessly
How F#$% did this happen?😠
@ConceptualJames @thehoffather @bernybelvedere @SonnyBunch @CathyYoung63 @chadfelixg @DrewHolden360
despite opioid prescriptions being at historic lows
Millions suffering & dying needlessly
How F#$% did this happen?😠
@ConceptualJames @thehoffather @bernybelvedere @SonnyBunch @CathyYoung63 @chadfelixg @DrewHolden360
Seen all of #Dopesick?
Few were willing to challenge OxyContin's rise. But now we have the benefit of hindsight
Here are just some of the unethical, immoral & criminal acts of Purdue Pharma the series exposes
As the Sackler Family likes to say: Judge For Yourselves
THREAD 1/18
Few were willing to challenge OxyContin's rise. But now we have the benefit of hindsight
Here are just some of the unethical, immoral & criminal acts of Purdue Pharma the series exposes
As the Sackler Family likes to say: Judge For Yourselves
THREAD 1/18
2/18
Purdue Pharma had prior experience with time-release opioids. Their morphine painkiller MS Contin was abused, diverted & highly coveted on the street. They knew all along
And yet, they moved forward with OxyContin, claiming it was safe, nonaddictive & unappealing to addicts
Purdue Pharma had prior experience with time-release opioids. Their morphine painkiller MS Contin was abused, diverted & highly coveted on the street. They knew all along
And yet, they moved forward with OxyContin, claiming it was safe, nonaddictive & unappealing to addicts
3/18
Despite having ZERO studies or data to claim OxyContin was less addictive than other opioids, the FDA granted them a label saying so
FDA Review Officer Curtis Wright secretly allowed Purdue to help write their own FDA review. Then he quit to go work for them at almost 400k
Despite having ZERO studies or data to claim OxyContin was less addictive than other opioids, the FDA granted them a label saying so
FDA Review Officer Curtis Wright secretly allowed Purdue to help write their own FDA review. Then he quit to go work for them at almost 400k
Seen #Dopesick ep 6?
I bet you were appalled by the "blood charts" & manipulated data Rick & Randy uncovered. Think that can't be real? No way #PurduePharma actually did that?
Let's start from the beginning. This is what a normal, scientific chart should look like...
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I bet you were appalled by the "blood charts" & manipulated data Rick & Randy uncovered. Think that can't be real? No way #PurduePharma actually did that?
Let's start from the beginning. This is what a normal, scientific chart should look like...
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The last chart had even intervals up the Y-axis. Totally normal. We learned how to read these in 6th grade
But #PurduePharma knew the data undermined the claim that OxyContin had fewer "peaks & valleys"
So they made a new one. Look at the Y-axis. Notice anything strange?
The last chart had even intervals up the Y-axis. Totally normal. We learned how to read these in 6th grade
But #PurduePharma knew the data undermined the claim that OxyContin had fewer "peaks & valleys"
So they made a new one. Look at the Y-axis. Notice anything strange?
3/5
Did you see the Y-axis intervals narrowing? Purdue was compressing data to mislead you.
FDA didn't approve. OxyContin didn't actually have "fewer peaks and valleys"
But Purdue kept going. Look at this Y-axis. 1-10 = 10-100. If I didn't point it out, would you have noticed?
Did you see the Y-axis intervals narrowing? Purdue was compressing data to mislead you.
FDA didn't approve. OxyContin didn't actually have "fewer peaks and valleys"
But Purdue kept going. Look at this Y-axis. 1-10 = 10-100. If I didn't point it out, would you have noticed?
#Dopesick
The history of FDA approvals of opioids
1995
At the time of approval, FDA believed the controlled-release formulation of OxyContin would result in less abuse potential, since the drug would be absorbed slowly
1/
fda.gov/drugs/informat…
The history of FDA approvals of opioids
1995
At the time of approval, FDA believed the controlled-release formulation of OxyContin would result in less abuse potential, since the drug would be absorbed slowly
1/
fda.gov/drugs/informat…
and there would not be an immediate “rush” or high that would promote abuse.
🔥In part, FDA based its judgment on the prior marketing history of a similar product (marketing created by Richard Sackler and Purdue Pharma), MS Contin, a controlled-release formulation of morphine
🔥In part, FDA based its judgment on the prior marketing history of a similar product (marketing created by Richard Sackler and Purdue Pharma), MS Contin, a controlled-release formulation of morphine
approved by FDA and used in the medical community since 1987 without significant reports of abuse and misuse.
Early 2000s (5 years)
Reports of overdose and death from prescription drug products, especially opioids, began to rise sharply, with Oxy at the center.
3/
Early 2000s (5 years)
Reports of overdose and death from prescription drug products, especially opioids, began to rise sharply, with Oxy at the center.
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