Discover and read the best of Twitter Threads about #CCTA
Most recents (5)
1/ SGLT2 inhibition initiation in the acute hospital setting? This trial showed significant benefit — REGARDLESS of ejection fraction — safe, and with incrementally added benefit when started early. EMPULSE Trial, Nature Medicine, 2022 ♥️ 
2/ SGLT2 inhibition for HFpEF? This trial showed SGLT2 inhibitors to have mortality benefit with EF > 40%, regardless of diabetes status. HFpEF represents a population of patients that beyond diuretic use, has historically been difficult to treat. DELIVER Trial, NEJM 2022 ♥️
1/ Two things..🧵
1️⃣ We need to complete registration!
You / someone you know:
👉Had LDL 160 or under before keto
👉LDL increased to 190 or more on keto
👉HDL 60 or more
👉Triglycerides 80 or below
👉2 or more years on keto
Go to LMHRstudy.com & see if u/they qualify
1️⃣ We need to complete registration!
You / someone you know:
👉Had LDL 160 or under before keto
👉LDL increased to 190 or more on keto
👉HDL 60 or more
👉Triglycerides 80 or below
👉2 or more years on keto
Go to LMHRstudy.com & see if u/they qualify
2/ Participants get:
🧬 Genetic testing
🩸Wide spectrum bloodwork
🫀 Advanced #CCTA scans
🚨🚨🚨YOU can help us get our target of 100 participants. Please do!
👉👉👉LMHRstudy.com
🧬 Genetic testing
🩸Wide spectrum bloodwork
🫀 Advanced #CCTA scans
🚨🚨🚨YOU can help us get our target of 100 participants. Please do!
👉👉👉LMHRstudy.com
3/ Please consider:
✅ Retweeting this tweet thread
✅ Sharing this thread or its contents in #Keto and #Carnivore #Facebook groups
✅ Sharing on #Instagram
✅ ... and, of course, you may already know people personally who fit this profile -- please reach out to them!
✅ Retweeting this tweet thread
✅ Sharing this thread or its contents in #Keto and #Carnivore #Facebook groups
✅ Sharing on #Instagram
✅ ... and, of course, you may already know people personally who fit this profile -- please reach out to them!
1/ #Study #MegaThread
A new study dropped with a trove of data I've long waited for around #CCTA/#CAC scans and #LDL #Cholesterol
✅ >23k studied (!)
✅ Largest sample of CCTA w/ ≥190 #LDL to date (!)
✅ Very uniform study population
Let's unpack...
jamanetwork.com/journals/jaman…
A new study dropped with a trove of data I've long waited for around #CCTA/#CAC scans and #LDL #Cholesterol
✅ >23k studied (!)
✅ Largest sample of CCTA w/ ≥190 #LDL to date (!)
✅ Very uniform study population
Let's unpack...
jamanetwork.com/journals/jaman…
2/ First, be sure to check out this short thread from the lead author, @MaBMortensen.
2 quick notes:
a) While there'll be lots of data appreciated by LDL skepticism, @MaBMortensen maintains LDL-C is still "an important causal RF"
b) Usual epi caveats, etc
2 quick notes:
a) While there'll be lots of data appreciated by LDL skepticism, @MaBMortensen maintains LDL-C is still "an important causal RF"
b) Usual epi caveats, etc
3/ Okay, so if you've followed me a while, you know just how incredibly thankful I am of studies that seek to avoid common risks of selection bias (Even if entirely unintended).
This study had the distinct advantage of categorically scooping its population directly...
This study had the distinct advantage of categorically scooping its population directly...
The NEW @AHAScience @ACCinTouch @ASE360 @accpchest @SAEMonline @Heart_SCCT @SCMRorg Guideline for the Evaluation and Diagnosis of Chest Pain has been released. #CPguideline
jacc.org/doi/10.1016/j.…
Here are highlights for #YesCCT: (1/17)
jacc.org/doi/10.1016/j.…
Here are highlights for #YesCCT: (1/17)
(2/17) #CCTA receives the highest level of recommendation (1A) in new US #CPGuideline
Guideline sponsored by: @AHAScience @ACCinTouch @ASE360 @accpchest @SAEMonline @Heart_SCCT @SCMRorg
In this CP Guideline Tweetorial the (Level of Recommendation is in parentheses).
Guideline sponsored by: @AHAScience @ACCinTouch @ASE360 @accpchest @SAEMonline @Heart_SCCT @SCMRorg
In this CP Guideline Tweetorial the (Level of Recommendation is in parentheses).
(3/17) Acute CP | Intermediate Risk & ⛔known CAD: After ruling out ACS, CCTA is useful to exclude plaque & obstructive CAD as a first line approach (1A) ✅ #CPguideline
Debate CAC vs CTA in primary prevention?
I will start with a provocative statement
Screening, foundational strategy for decades in prev cardio is a seductive paradigm
Its so 1990’s
We are barking on the wrong tree
In 2020, I will explain why this strategy is a fallacy
#ASPC2020
I will start with a provocative statement
Screening, foundational strategy for decades in prev cardio is a seductive paradigm
Its so 1990’s
We are barking on the wrong tree
In 2020, I will explain why this strategy is a fallacy
#ASPC2020
#1 Both primary and secondary prevention lower disease burden and outcomes
#2 Marginal benefit of extensive screening
#3 Whats left to screen? Majority already treatment candidates
#4 Our stakeholders asking for "derisking" vs "screening"
#APSC2020
#2 Marginal benefit of extensive screening
#3 Whats left to screen? Majority already treatment candidates
#4 Our stakeholders asking for "derisking" vs "screening"
#APSC2020
-Despite being being an avid advocate of CAC screening in past, it was time to move on
-Showed 1 in 2 statin candidates have #PowerOfZero
-Proposed CAC as SDM tool
-Concept confirmed in 3 other cohorts, better than any neg marker, cost-effective, and no statin treatment benefit
-Showed 1 in 2 statin candidates have #PowerOfZero
-Proposed CAC as SDM tool
-Concept confirmed in 3 other cohorts, better than any neg marker, cost-effective, and no statin treatment benefit
