Discover and read the best of Twitter Threads about #Bedaquiline

Most recents (3)

We did it! In a landmark verdict, the Indian Patent Office rejected Johnson and Johnson’s patent application that would have extended the monopoly on key anti-TB drug #Bedaquiline! @ptisile and I – both of us TB survivors -- had filed pre-grant opposition against the application
@Ptisile @StopTB @TbDivision @doctorsoumya @WHO Bedaquiline is key anti-TB drug for people with severe forms of TB that has shown to improve cure rates and have lesser side effects. I can't think of a better news ahead of #WorldTBDay2023 !
Thank you for the all wishes! This victory wouldn't have been possible without @MSF_Ind @priyamliz @singh_jyotsna and Roshan.
Read 3 tweets
In our @LancetMicrobe paper we report 671 Mtb genomes 🧬from 391 patients with drug #resistant #tuberculosis in KwaZulu-Natal South Africa sampled over 6 years.

We screened for resistance to #bedaquiline, a drug now central to effective #TB treatment.

➡️tinyurl.com/y5zapnbk
We found ~4% of patients harboured #Mtb with variants in genes known to mediate #resistance to bedaquiline/clofazimine.

Phylogenetic analyses show repeated & independent acquisitions of resistance variants, including onward transmission of resistant strains across South Africa.
Bedaquiline is a reasonably new, but now cornerstone, drug in the fight against #DRTB.

The lack of routine #bedaquiline susceptibility testing may allow these #resistant strains to continue to spread, unwatched, posing further significant challenges to #TB treatment & control.
Read 4 tweets
1/ Yury is the 1st person to complete treatment at @MSF’s #tuberculosis treatment programme in #Belarus. Here's his story in a few tweets ⬇
2/ Yury is celebrating a moment he thought would never arrive: he has been cured of a complicated form of TB bit.ly/2vQFBl3 #XDRTB
3/ “I thought everything had ended. That everybody would turn away from me.” Yury learned he was sick with #XDRTB in 2013. #tuberculosis
Read 8 tweets

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