Discover and read the best of Twitter Threads about #BarcelonaBeta
Most recents (7)
Tot a punt per la V Trobada anual de la Fundació, t’hi esperem! 
Comencem la Trobada anual “Passat, present i futur de la recerca en Alzheimer” amb l’il·lusionista @jorgeblass
Seguim amb el Dr. @jordicami, primer director de la Fundació i actual vicepresident i patró vitalici, per repassar la posada en marxa del projecte i les primeres fites aconseguides.
👉Una investigación liderada por el #BarcelonaBeta, con el apoyo de la @FundlaCaixa, demuestra la asociación entre marcadores del #Alzheimer y un aumento de síntomas de ansiedad y depresión durante el confinamiento por la #Covidー19 barcelonabeta.org/es/actualidad/…
🔎 El estudio es un primer paso para entender el potencial efecto de la pandemia en las enfermedades neurodegenerativas.
Las investigadoras del #BarcelonaBeta, la Dra. @ArenazaEider, líder del proyecto, y @MugeAkinci, autora principal, nos hablan sobre los resultados 👇
Las investigadoras del #BarcelonaBeta, la Dra. @ArenazaEider, líder del proyecto, y @MugeAkinci, autora principal, nos hablan sobre los resultados 👇
🧠 El estudio investigó la salud mental de mujeres y personas cuidadoras porque, generalmente, reportan mayores niveles de ansiedad y depresión. A lo que hay que sumar que las personas cuidadoras son, mayoritariamente, mujeres.
And another from my former institution, this as a first author!
We found that higher levels of GFAP, an #astroglial marker, were related to higher glucose metabolism 🧠in early stages of #Alzheimer's, especially when GFAP was measured in blood🩸
link.springer.com/article/10.100…
We found that higher levels of GFAP, an #astroglial marker, were related to higher glucose metabolism 🧠in early stages of #Alzheimer's, especially when GFAP was measured in blood🩸
link.springer.com/article/10.100…
This suggests that a higher astrocytic reactivity in early stages of Alzheimer's, probably in response to #amyloid accumulation, is related to higher glucose consumption. This may (in part) explain why we see higher levels of glucose metabolism in these early stages.
This relationship between GFAP and glucose metabolism became negative in subjects with tau pathology (A+T+), suggesting a failure to sustain the higher energetic demands required by astrocytes. Notably, this was observed in areas of typical AD hypometabolism seen in later stages.
🚨 Our paper on p-tau231 and p-tau217 as blood 🩸biomarkers 🧪 in preclinical #Alzheimers 🧠 is now published in @NatureMedicine
nature.com/articles/s4159…
@goteborgsuni #BarcelonaBeta @fpmaragall
@hospitaldelmar @IMIM_research @KingsCollegeLon
🧵 summary
👇🏾
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nature.com/articles/s4159…
@goteborgsuni #BarcelonaBeta @fpmaragall
@hospitaldelmar @IMIM_research @KingsCollegeLon
🧵 summary
👇🏾
(1/6)
We investigated 6 blood 🩸 biomarkers in 397 cognitively unimpaired individuals of the ALFA study at #BarcelonaBeta :
🟤 p-tau181
🟣 p-tau217
🟠 p-tau231
🟢 GFAP
🔵 NfL
🔴 Abeta42/40
and all were significantly increased in preclinical #Alzheimers
but ..
(2/6)
🟤 p-tau181
🟣 p-tau217
🟠 p-tau231
🟢 GFAP
🔵 NfL
🔴 Abeta42/40
and all were significantly increased in preclinical #Alzheimers
but ..
(2/6)
Plasma 🩸 p-tau231 🟠 and p-tau217 🟣 had:
👉🏾 the highest increase with the lowest #amyloid burden
👉🏽 the strongest association with amyloid PET
👉🏿 a significant association with longitudinal increases in amyloid PET uptake
(3/6)
👉🏾 the highest increase with the lowest #amyloid burden
👉🏽 the strongest association with amyloid PET
👉🏿 a significant association with longitudinal increases in amyloid PET uptake
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Un nuevo estudio del #BarcelonaBeta, con el apoyo de la @FundlaCaixa, ha investigado la relación entre las hiperintensidades de la materia blanca y la carga de amiloide.
Los resultados se han publicado en la revista científica @braincomms ⬇️ academic.oup.com/braincomms/art…
Los resultados se han publicado en la revista científica @braincomms ⬇️ academic.oup.com/braincomms/art…
Las hiperintensidades de la materia blanca son lesiones de este tejido cerebral de origen vascular que se han asociado con un mayor riesgo de enfermedad de Alzheimer.
Puedes leer más sobre esta línea de investigación aquí ⬇️
barcelonabeta.org/es/actualidad/…
Puedes leer más sobre esta línea de investigación aquí ⬇️
barcelonabeta.org/es/actualidad/…
En este nuevo estudio han participado 662 personas de cohortes asociadas al consorcio europeo @IMI_AMYPAD, una colaboración que ha supuesto una gran mejora en el conocimiento del Alzheimer mediante la tomografía por emisión de positrones.
✈️ The #BarcelonaBeta @fpmaragall 💚 team is heading to #AAIC2022 in San Diego 👩🔬👩🏿🔬👩🏾⚕️👩🏽💻
👉🏾 Keep an eye 👀 on our hashtag #BarcelonaBeta for updates on presentations from our team!
Please RT!
@alzassociation @ISTAART #ENDALZ
👉🏾 Keep an eye 👀 on our hashtag #BarcelonaBeta for updates on presentations from our team!
Please RT!
@alzassociation @ISTAART #ENDALZ
👩🏾💼 We will be presenting new results on our #Alzheimer research in neuroimaging, biomarkers, resilience, air pollution, life-style, sleep, genetics, sex and gender, cognition, and more! 🔬🧪🧠🧬🧑🏾🔬
@alzassociation @ISTAART #ENDALZ #AAIC2022
@alzassociation @ISTAART #ENDALZ #AAIC2022
📢 and we have open-positions to join our team at #BarcelonaBeta @fpmaragall 💚 !
👉🏾 Do not hesitate to write us or just meet ☕️ at #AAIC2022 and have a chat !
@alzassociation @ISTAART #ENDALZ
👉🏾 Do not hesitate to write us or just meet ☕️ at #AAIC2022 and have a chat !
@alzassociation @ISTAART #ENDALZ
Our new paper in paper in blood 🩸 and CSF p-tau in #preclinical #Alzheimers 🧠 is out in @EmboMolMed ‼️
A great collaboration between #BarcelonaBeta @fpmaragall and @goteborgsuni
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embopress.org/doi/full/10.15…
A great collaboration between #BarcelonaBeta @fpmaragall and @goteborgsuni
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embopress.org/doi/full/10.15…
A collaboration between great scientists!
@TommyKakari @NicholasAshton @Marta_Mila_ @JuandoGispert @gesalbla @CarolinaMingui2 @ArenazaEider @GSBenavides and all the team of #BarcelonaBeta and the Blennow/Zetterberg lab in @goteborgsuni
A summary below
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@TommyKakari @NicholasAshton @Marta_Mila_ @JuandoGispert @gesalbla @CarolinaMingui2 @ArenazaEider @GSBenavides and all the team of #BarcelonaBeta and the Blennow/Zetterberg lab in @goteborgsuni
A summary below
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We investigated novel CSF and plasma p‐tau biomarkers in the preclinical stage of the Alzheimer’s continuum and compared them with the widely used CSF Mid‐p-tau181.
We hypothesized that they change when subtle changes in Aβ are detectable.
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We hypothesized that they change when subtle changes in Aβ are detectable.
3/n
