Discover and read the best of Twitter Threads about #ranitidine
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Commonly used drug for acidity #Ranitidine may increase the risk of #cancers
1. Ranitidine (sold under the brand name Rantac, zinetac, aciloc) is commonly used for treating acidity. Analysis of ranitidine samples has shown contamination by a chemical NDMA (nitrosodimethylamine)
1. Ranitidine (sold under the brand name Rantac, zinetac, aciloc) is commonly used for treating acidity. Analysis of ranitidine samples has shown contamination by a chemical NDMA (nitrosodimethylamine)
2. Ranitidine use caused higher incidence of pharynx, oesophagus, stomach, liver, pancreas and colorectal cancers. Ref: Cancers (Basel), Jan 2021
3. USFDA banned ranitidine in April 2020. In India, it is not banned, but was removed from National list of essential medicines in Sep
3. USFDA banned ranitidine in April 2020. In India, it is not banned, but was removed from National list of essential medicines in Sep
Conclusion: It is better to avoid use of ranitidine for treating acidity due to a higher risk of gastro-intestinal cancers with its intake.
#MedTwitter #Acidity
#MedTwitter #Acidity
Doctors of all people, MUST NOT scare monger #ranitidine
Dropping from 'essential list' DOES NOT mean it is banned
It can be used and is still in use
'CERTAIN' manufacturer's Ranitidine products were found contaminated with NDMA - a potential...
Dropping from 'essential list' DOES NOT mean it is banned
It can be used and is still in use
'CERTAIN' manufacturer's Ranitidine products were found contaminated with NDMA - a potential...
..cancer causing agent.
US FDA has been investigating this since 2019.
In fact, a study done by the US FDA on conversion of ranitidine into significant NMDA under normal physiology conditions showed that it did not change for worse.
There is NO EVIDENCE that Ranitidine use...
US FDA has been investigating this since 2019.
In fact, a study done by the US FDA on conversion of ranitidine into significant NMDA under normal physiology conditions showed that it did not change for worse.
There is NO EVIDENCE that Ranitidine use...
..can cause cancer or HAS caused cancer in humans till now.
Certain batches of OTHER drugs too - like Metformin and Losartan were also found to have NDMA impurity - this DOES NOT mean cancers are caused by use of these drugs
aninews.in/news/national/…
Certain batches of OTHER drugs too - like Metformin and Losartan were also found to have NDMA impurity - this DOES NOT mean cancers are caused by use of these drugs
aninews.in/news/national/…
Thread #valsartan #ranitidine NDMA impurity.....
Last year when the US FDA sent out a warning letter to China's Zhejiang Huahai (ZHP) for NDMA impurities, a known carcinogen, a few large Indian drug makers may have felt the chill...one of them is Hyderabad-based Hetero Drugs.
Last year when the US FDA sent out a warning letter to China's Zhejiang Huahai (ZHP) for NDMA impurities, a known carcinogen, a few large Indian drug makers may have felt the chill...one of them is Hyderabad-based Hetero Drugs.
Following ZHL, Hetero is learnt to have changed the manufacturing process for valsartan API. Since it meant fewer stages of manufacturing, it more or less became an industry norm to adapt to a new way to cut costs; being ahead in the market competition was a priority
ZHP was reported to have used sodium azide, which leads to higher yields as compared to tributyltin azide, that was used by Sandoz. However, what was unclear was the use of solvent dimethylformamide may lead to carcinogens, though in small quantities. Some chemistry..
