Discover and read the best of Twitter Threads about #oscillations

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All vertebrate #brains have #parvalbumin #interneurons, but in mammals they play a critical role in the function of the #cortex. @ellie_bucher‘s debut paper in Brain Structure and Function surveys the field to tell this emerging and exciting story. rdcu.be/cni5M Image
Parvalbumin equips these #neurons for sustained fast firing, synchronizing large areas of cortex to focus attention. Linked in vast networks which buzz with gamma #oscillations, their outputs target cell bodies and axons of principal neurons to control their interactions. Image
Uniquely among interneurons, #perineuronal nets and #myelin anchor and stabilise the cell bodies and axons of basket cells, tightly regulating #plasticity to bind their networks into functional structures after critical periods pass. Image
Read 5 tweets
Out today in @PNASNews we reveal how Ca2+ signals coordinate the flow of milk from secretory alveoli to the nipple during lactation doi.org/10.1073/pnas.2… A wonderful team effort by @Stevenson_alex2 @DrYassum @tenealestewart @DrNickCondon @BethLloydLewis @LabEthan @_adamewing 1/
Using volumetric #calcium imaging we show how #oxytocin (released in response to suckling) produces Ca2+ #oscillations in mammary basal cells, causing them to contract and repetitively deform the innermost layer of secretory cells (shown here in red) 2/
We show that Ca2+ release from internal stores and influx across the cell membrane are sufficient for these contractions to occur but that Ca2+ influx is necessary to sustain them 3/
Read 6 tweets

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