Discover and read the best of Twitter Threads about #nasopharyngeal
Most recents (6)
1/4 "Researchers from the University of Colorado Boulder found in a 2019 study that the average house is prone to “#indoor #air quality levels on par with a polluted major city.”"
eurekalert.org/news-releases/…
eurekalert.org/news-releases/…
1/4 "Using droplet digital PCR, we found #SARSCoV2 #nucleocapsid #RNA in 7 out of 9 #adenoid and 15 out of 22 tonsil formalin-fixed, paraffin-embedded tissue blocks from post-COV individuals, despite #negative #nasopharyngeal swab #PCRs at the time of surgery..."
#pediatric
#pediatric
2/4 "... variation in memory B cell frequencies and serum-neutralizing antibody titers we observed further highlighted heterogeneity of responses that may leave some #children prone to #repeat #infection."
#pediatric #viral #persistence despite #negative #nasopharyngeal #PCR
#pediatric #viral #persistence despite #negative #nasopharyngeal #PCR
3/4 "... activated cells in these #tissues after infection may also contribute to delayed or #prolonged #sequelae of #COVID19, including long-COVID-19 and #multisystem #inflammatory syndrome in children,..."
#LongCovidKids #PASC
#LongCovidKids #PASC
1/N "... 0.5% povidone iodine (PVP-I) #mouthrinse/gargle for 30 s can reduce #SARSCoV2 virus infectivity to below detectable levels. PVP-I can even interrupt SARS-CoV-2 attachment to #oral & nasopharyngeal tissues & lower the viral particles in the saliva & respiratory droplets."
2/N
#SARSCoV2 #infection #prevention #oral #nasopharyngeal #hygiene
Source:
pubmed.ncbi.nlm.nih.gov/33747261/#:~:t….
@DropletDiaries
#SARSCoV2 #infection #prevention #oral #nasopharyngeal #hygiene
Source:
pubmed.ncbi.nlm.nih.gov/33747261/#:~:t….
@DropletDiaries
3/N "[... we propose immediate use of PVP-I in healthcare workers & their patients as described to minimise risk of spread of disease as an addition to currently recommended PPE used during management of #COVID19 patients.]"
#SARSCoV2 #oral #hygiene
ncbi.nlm.nih.gov/pmc/articles/P…
#SARSCoV2 #oral #hygiene
ncbi.nlm.nih.gov/pmc/articles/P…
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses.
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses.
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic.
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic.
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus.
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus.
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component.
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component.
I had a similar discussion in a forum recently and this was my opinion. A thread..
As long as we started monitoring COVID in Africa from Feb 2020 then there will be lots of unexplained observations.
IMHO
As long as we started monitoring COVID in Africa from Feb 2020 then there will be lots of unexplained observations.
IMHO
1) The #SARSCoV2 most likely entered #Africa way before Feb 2020, probably October 2019. Unfortunately archiving of clinical #nasopharyngeal swabs is challenging, so we might not know for sure ...
2) Most Africans like so many in other parts of the world have had infections with non-#COVID19 #coronaviridiae during their lifetime so if the cross reacting #Tcell stories are to be believed then lots of people already had them and might have offered some sort of protection
