Discover and read the best of Twitter Threads about #mdphd
Most recents (2)
Cognitive heterogeneity in Parkinson’s disease: A mechanistic view cell.com/neuron/fulltex…
Our thoughts on #synuclein strains, #Alzheimer pathology, and individual genetic and biomarker characteristics in why individuals with #Parkinson disease manifest so differently. 1/n
Our thoughts on #synuclein strains, #Alzheimer pathology, and individual genetic and biomarker characteristics in why individuals with #Parkinson disease manifest so differently. 1/n
We review how cognition looks in #Parkinsons (short answer: lots of different ways in different people). We review treatment options for cognitive impairment in PD (short answer: not many). We argue that mechanistic focus is needed for better treatment options to emerge. 2/n
Mechanistically, we focus on cell-to-cell spread of pathological #synuclein (aSyn). We think evidence for aSyn spreading and for strains (conformations) of aSyn w different biological behaviors and subsequent cognitive consequences in aSyn diseases is strong. 3/n
We are currently entering week 2 of isolation/quarantine with two kids under 3 with symptomatic covid. Here is how we got here. #tweetiatrician #mdphd #covid19 #deltavariant 1/n
Three weeks ago, my vaccinated dad left for a week long camping trip with 6 other vaccinated guys (including my uncle). They spent time outside, in the mountains, hiking, fishing, etc. They did not share tents. They did not share cars. 2/n
On 8/4 my parents, whom we have been in a bubble with since the start of the pandemic, came over for dinner to celebrate my birthday; on 8/6 they babysat my 2yo and 9mo so my husband and I could go out to dinner (we ate out doors, in a socially distanced setting). 3/n
