Discover and read the best of Twitter Threads about #lysis

Most recents (3)

#WeekendLecture
#Tenecteplase #TNK
Part 1
✅3rd generation rtPA
🧬Targeted genetic upgrade
3 specific alterations to #alteplase molecule:
👉⬆️Half life
👉⬆️Binding affinity for #fibrin
👉⬆️Resistance to inactivation by #PAI-1
bit.ly/3pqbEb1 Image
#WeekendLecture
#TNK

👉⬆️T1/2 allows single bolus dosing and⬆️clot exposure to TNK
👉Higher affinity to fibrin-rich clots & + potent/faster clot #lysis vs alteplase
👉 < consumption of fibrinogen/plasminogen/ a2- antiplasmin👉⬇️systemic fibrinolytic effect👉⏬risk for bleeding Image
#WeekendLecture
#TNK
First analysis in stroke patients was a #dose-scalation safety study
There was no #symptomatic ICHs in dosis of 0.1-0.2-0.4mg/kg, and 15% (2 of 13) in 0.5mg/kg
No differences in clinical outcomes
bit.ly/3DNHamV ImageImage
Read 11 tweets
1/ Welcome to the first part of a #Tweetorial series on #VenousDisease.

🩸To begin how about we talk about the main player in the game- C.L.O.T. (and why you should care about it)

#Cardiotwitter #Irad #fellows #fellowtwitter #medthread #clot #medtwitter #clottwitter
3/ All clots ARE NOT born equally! There is a difference! Image
Read 34 tweets
Mwanasayansi mwenye ubobezi wa kimataifa kwenye maswala ya vitendanishi na vipimo (Diagnostics), Dr. Ally Mahadhy, aliandika haya kwenye ukurasa wake wa facebook, ni vyema wadau humu wakayapata ili kuongeza uelewa @Udadisi
@MariaSTsehai @fatma_karume
#ElimikaWikiendi
Uzi 👇🏽
"Kutakucha tu!

Tukiwa tupo kwenye taharuki juu ya kipimo cha corona (covid-19) hapa nchini, baada kutoa majibu ya positive kwa mbuzi na papai, naomba nitoe maoni yangu kama mdau katika tansia hii ya vitendanishi vya maabara (diagnostics). ..." /1
Nianze kwa kutangaza maslahi yangu binafsi kwenye mada husika. Mimi ni mtafiti kwenye eneo hili la vitendanishi (Medical and clinical diagnostics). Tasnifu (thesis) yangu ya umahiri (MSc in Biotechnolgy) iljikita kwenye kutengeneza njia (method) ya kutambua kwa haraka na wepesi/2
Read 61 tweets

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