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CKD-MBD - a commonly overlooked complication in our patient population
And one of the most under-prescribed drug (atleast in India) in the armamentarium is Cinacalcet
Here's a short thread on calcimimetics
#medtweetorial #nephtweetorial #iqraakidneyclub
And one of the most under-prescribed drug (atleast in India) in the armamentarium is Cinacalcet
Here's a short thread on calcimimetics
#medtweetorial #nephtweetorial #iqraakidneyclub
Mechanism of action?
As the name says -- a 'calcium' mimetic
Makes the CaSR in the parathyroid gland feel there's 'too much' calcium and suppresses PTH
As the name says -- a 'calcium' mimetic
Makes the CaSR in the parathyroid gland feel there's 'too much' calcium and suppresses PTH
How is it different from Active Vitamin D analogues?
While both aim to suppress PTH, their actions on Ca x P and FGF 23 levels are different
This could turn out to positively effect mortality outcomes? Let's find out
While both aim to suppress PTH, their actions on Ca x P and FGF 23 levels are different
This could turn out to positively effect mortality outcomes? Let's find out
Rituximab in membranous nephropathy!
Quick poll - Has recent evidence changed your practice as first line therapy in membranous nephropathy?
Quick poll - Has recent evidence changed your practice as first line therapy in membranous nephropathy?
Rituximab is crawling it’s way as part of immunotherapy in many diseases now
But does it warrant its use as 1st line therapy in all patients with MN?
Let’s see a few clinical implications:
Let’s see a few clinical implications:
How and when do you screen for BK virus Nephropathy at your setting?
An update on BK virus Nephropathy today morning at #iqraakidneyclub
@hafeeq_benil @JyotishGopinat2 @ranji72 @drferoz
An update on BK virus Nephropathy today morning at #iqraakidneyclub
@hafeeq_benil @JyotishGopinat2 @ranji72 @drferoz
BKVAN is a 2-hit disease - with 1) local environmental factors in the kidney (IRI, ureteral injury during transplant) and 2) immunosuppression playing a key role
Risk factors can be donor/recipient/procedure/virus-related:
Risk factors can be donor/recipient/procedure/virus-related:
Local factors are the reason why:
1) BKVAN can occur quite early in transplant
2) BKVAN is more common in renal than other solid organ transplants
1) BKVAN can occur quite early in transplant
2) BKVAN is more common in renal than other solid organ transplants
Thursday mornings at #iqraakidneyclub: Excellent short lecture by Dr Vinugopal on the use of Peritoneal Dialysis in Heart Failure/Cardiorenal Syndromes
Sharing a few slides below:
@hafeeq_benil @drferoz @ranji72 @JyotishGopinat2
#NephTwitter #cardiorenal
Sharing a few slides below:
@hafeeq_benil @drferoz @ranji72 @JyotishGopinat2
#NephTwitter #cardiorenal
How frequent have you started PD for refractory heart failure or CRS type 2?
Starting with the basics -- the classification (which always confuses me btw)
1 & 2 being primarily cardiac, 3 & 4 being primarily renal
1 & 3 being acute, 2 & 4 being chronic
1 & 2 being primarily cardiac, 3 & 4 being primarily renal
1 & 3 being acute, 2 & 4 being chronic
