Discover and read the best of Twitter Threads about #geneedited
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Wanted to try a twitter tutorial (our first, so bear with it) on the v. interesting #CRISPR issues raised by the recent birth of #geneedited #Calf "Cosmo", thx to @UCDavis researcher @BioBeef. Author @MeganMolteni gamely brought in some perspective but no technical critic, so....
The following are issues neglected or barely raised in the text but should be born in mind while reading the article, which described attempts to add the SRY sex "determining" gene and make all male animals: wired.com/story/a-crispr…
2 The researchers began w/a "crude portrait" #genome sequence (so the first embryos died because the researchers chose the wrong place to edit). The premise of #geneediting is precision but this requires EXACT knowledge of the target genome, which almost invariably is lacking.
