Discover and read the best of Twitter Threads about #flavivirus
Most recents (6)
*Tamanaviruses* - a primer (medium thread)
(1) Tamana bat virus (TABV) is a highly divergent #flavivirus that was isolated in 1974, from a bat trapped at the exit of Tamana cave, on the North slope of Trinidad's Mount Tamana.
(1) Tamana bat virus (TABV) is a highly divergent #flavivirus that was isolated in 1974, from a bat trapped at the exit of Tamana cave, on the North slope of Trinidad's Mount Tamana.
(2) TABV was identified at the Trinidad Regional #Virus Laboratory (TRVL) as part of a post-war virus discovery effort lead by the Rockefeller Foundation.
The #Tamana cave system comprises several large limestone caverns and is a roost for several species of bat.
The #Tamana cave system comprises several large limestone caverns and is a roost for several species of bat.
(3) Millions of bats fly out of Tamana cave exits to feed at dusk, making for an impressive spectacle.
Researchers at TRVL trapped #bats at cave exits, took samples from these bats and attempted to cultivate viruses.
Researchers at TRVL trapped #bats at cave exits, took samples from these bats and attempted to cultivate viruses.
Short #Jingmenvirus primer - medium thread.
Jingmenvirus is a recently identified group of segmented RNA viruses that are phylogenetically linked to unsegmented flaviviruses. They appear to infect a wide range of animal hosts, including humans.
Jingmenvirus is a recently identified group of segmented RNA viruses that are phylogenetically linked to unsegmented flaviviruses. They appear to infect a wide range of animal hosts, including humans.
Jingmenviruses (JMVs) contain two #flavivirus-related segments, as well as additional segments of unknown origin. It is thought that JMVs evolved from unsegmented flaviviruses.
doi.org/10.1073/pnas.1…
doi.org/10.1073/pnas.1…
The evolutionary significance of this shift to a segmented genome is unclear, but comparative studies of JMVs and flaviviruses may illuminating.
A #thread on our recent paper in @PLOSNTDs examining ecological #evidence-base for #DiseaseControl management practices for #KyasanurForestDisease #AcademicTwitter #Scicomm #OneHealth; paper led by @SarahBurthe from @MonkeyFever_ consortium
#Diseasecontrol strategies originate through endorsements by Governments/academia/authorities; they're often not field-tested robustly; even when they are, evidence is limited to one sector (cf. #OneHealth #Intersectoral approaches);
#publichealth approaches ought to be contextual & their effectiveness ought to be evaluated, yet strategies for disease control often spread through word of mouth and are sometimes untested;
...Repasemos la enfermedad por el #VirusWestNile (#WNV):
🔘WNV es un arbovirus zoonótico emergente extendido por todo el 🌎
🔘Se transmite principalmente por la picadura de mosquitos.
🔘Las aves suelen ser el reservorio natural (migración ayuda a propagación).
Abro 🧶⬇️
🔘WNV es un arbovirus zoonótico emergente extendido por todo el 🌎
🔘Se transmite principalmente por la picadura de mosquitos.
🔘Las aves suelen ser el reservorio natural (migración ayuda a propagación).
Abro 🧶⬇️
🔘El virus puede resultar patogénico en humanos 👩🦰🧑🦰y en equinos 🐴
🔘Es una de las enfermedades incluidas en el Reglamento Sanitario Internacional de la #OMS, así como en la lista de enfermedades de declaración obligatoria de la #OIE
🔘Su diagnóstico diferencial es amplio
🔘Es una de las enfermedades incluidas en el Reglamento Sanitario Internacional de la #OMS, así como en la lista de enfermedades de declaración obligatoria de la #OIE
🔘Su diagnóstico diferencial es amplio
La infección por WNV suele ser asintomática (60-80%)
Cuando es sintomática, se caracteriza por #fiebre, #cefalea, #artromialgias y malestar general.
Hasta en el 50% puede aparecer un #rash maculopapular (tronco y extremidades)
Cuando es sintomática, se caracteriza por #fiebre, #cefalea, #artromialgias y malestar general.
Hasta en el 50% puede aparecer un #rash maculopapular (tronco y extremidades)
Flaviviruses on the rise, also in Germany: spon.de/afAy7 (German article) #virus #virology #flavivirus #emergingdiseases #zika #westnilevirus #dengue
@ChanasitJonas has more on this
En los últimos años el #dengue ha sido incontrolable. En Argentina la peor epidemia fue en 2016.Uruguay es aún una isla. Hay algunas vacunas nuevas. @GamarnikLab
Estudiar el dengue permite entender muchos otros #flavivirus que también tienen importancia para la salud pública.@GamarnikLab
