Discover and read the best of Twitter Threads about #fattyliverdisease

Most recents (2)

☪️ #4 and #5!
One of my personal favorite intersections: #Ramadan and #NAFLD

Things that are established: Ramadan fasting does not make fatty liver disease worse

But does it make it better?
The empiric answer would be YES, but how? let’s dive into the nuance
🧵1/
Observational data suggest that in patients with #fattyliverdisease, Ramadan tends to ⬇️ LFTs and ⬆️glycemic function

tinyurl.com/bdctcav8

Retrospective data seems to agree with this:

tinyurl.com/2nwd5zhc

These changes involve ⬇️ in A1c, BMI, and FIB4 scores❗️

2/
So the available data (though limited) establishes that Ramadan fasting seems to improve LFTs and leads to valuable reductions in disease-related indices like fibrosis scores

The more interesting question though, is

HOW❓🧐

3/
Read 9 tweets
A new research study in @bmj_latest doi.org/10.1136/bmj.m3… finds the risk to die early (<70yrs) increases with irregularity & length of women’s #menstrualcycle irregularity, with premature mortality mostly due to #cardiovasculardisease. What's it mean for women with #PCOS? 1/13
PCOS affects 10% of women worldwide & irregular menstrual cycles are a common symptom. Many of the women in this study likely have PCOS. Understandably, the higher rates of premature mortality reported will be worrying to women with PCOS. But what causes period irregularity? 2/13
Increased levels of male hormones #androgens are a cause of irregular periods (see: doi.org/10.1177/204201…; doi.org/10.1210/en.201…) and also impact on pancreatic beta cell function (doi.org/10.2337/db20-0…) causing #insulinresistance 3/13
Read 14 tweets

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