Discover and read the best of Twitter Threads about #crizanluzumab

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Dr. Alan Anderson here to present #crizanluzumab (which is approved for age >16 to prevent VOE) and its effect on #priapism. Long prescreening to capture these occ events. Needed 4 in prescreening 14 weeks. 1/n #ASH22 Image
24 patients met the eligibility criteria. Received 5 mg/kg and then q4 weeks and checked outcome at week 26 and treated for 52 weeks. Also reported #PRO. #ASH22 2/n
This is the baseline data -- first reported at age 13-17 years, often daily or every other day. If this is surprising to you, think about how you are asking your #SCD pts about #priapism? It has a significant impact on their life! #ASH22 3/n Image
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