Discover and read the best of Twitter Threads about #cancerresearch
Most recents (17)
💉💉 I'm A Believer 💉💉
I thought love was only true in fairytales...
I thought love was only true in fairytales...
I believe this virus is scary. >
I believe the 💉s help prevent against serious illness & death. >
💉 Here's Where the Story Ends ~ snoRNAs 💉
Small nucleolar RNAs (snoRNAs) are small bits of RNA which direct gene expression. They are involved in transcription, and translation of proteins which cause cancer. snoRNAs are biomarkers for tumerogenesis. >
Small nucleolar RNAs (snoRNAs) are small bits of RNA which direct gene expression. They are involved in transcription, and translation of proteins which cause cancer. snoRNAs are biomarkers for tumerogenesis. >
N1-methyl-pseudouridine (m1Ψ) is a snoRNA product.
N1-methyl-pseudouridine is also an ingredient in the COVID mRNA 💉.
It's used to insure strong lasting translation of the spike protein in the body. >
N1-methyl-pseudouridine is also an ingredient in the COVID mRNA 💉.
It's used to insure strong lasting translation of the spike protein in the body. >
>
Turn Down For What ~ Wheel of Cancer
Annoyed Citizen goes in depth on the topic of 💉 synthetic mRNA causing cancer. >
Annoyed Citizen goes in depth on the topic of 💉 synthetic mRNA causing cancer. >
Here is the link, if the page comes up in German, click the button on the top left for the English translation
open.substack.com/pub/genervter/…
open.substack.com/pub/genervter/…
🦴 Bad to the Bone 🦴
The 2020 SARS2/HIV research of University of Alberta scientist Shokrollah Elahi portended this. >
Teen boy died from leukemia just a day after diagnosis mol.im/a/12020923 via @MailOnline
The 2020 SARS2/HIV research of University of Alberta scientist Shokrollah Elahi portended this. >
Teen boy died from leukemia just a day after diagnosis mol.im/a/12020923 via @MailOnline
We’re pleased to announce the 2023 NAS Awards recipients! These 16 individuals are honored for their extraordinary scientific achievements in a wide range of fields spanning the physical, biological, and medical sciences. bit.ly/402ovjs #NASaward #Science #Awards
Join us in congratulating Kirk Bryan Jr. of NOAA Geophysical Fluid Dynamics Laboratory & @Princeton, winner of the 2023 Alexander Agassiz Medal for pioneering and visionary work in oceanography and climate science! Learn about his work: bit.ly/3HoGh91#NASawa… #Climate
We are honoring David J. McComas of @Princeton with the 2023 Arctowski Medal for his pioneering contributions to experimental space plasma physics! You can read more about his achievements here: bit.ly/3kqUFog #NASaward #Space #Physics
1/6 @illumina just announced the $200 whole genome 🧬 The most powerful machines in the Novaseq X series can produce 20,000 genomes a year, so how can we make sense of all that data in #cancerresearch? COSMIC has the answers 💡 #IGF
2/6 🧬Rapidly prioritise genes which have evidence of a causal role in cancer with #COSMICCGC, and understand their biological role via our Hallmarks Annotation: bit.ly/3SFN1SO
3/6 🚘 Separate driver from passenger mutations with #COSMICCMC - where mutations are classified into tiers based on bioinformatic analysis from sources such as @clinvar #DnDs ratios and core-COSMIC data: bit.ly/3y5XoaO
Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo
Its a signal getting brighter but 1 among many wins of #CancerResearch that needs unlimited Public support & resources/ facilitation from Govt/Charities pubmed.ncbi.nlm.nih.gov/35660797/
Its a signal getting brighter but 1 among many wins of #CancerResearch that needs unlimited Public support & resources/ facilitation from Govt/Charities pubmed.ncbi.nlm.nih.gov/35660797/
It's neither the 1st nor will it be the last spectacular win of cancer research against one of the several hundred forms or subtypes of human cancers
100+ y ago, early-stage Breast/ Thyroid/ Kidney/ Oral/ Stomach & other cancers then considered fatal were cured by surgery alone
100+ y ago, early-stage Breast/ Thyroid/ Kidney/ Oral/ Stomach & other cancers then considered fatal were cured by surgery alone
80+ y ago, skin cancers, early-stage cervix, oral and larynx cancers were magically cured by Radiotherapy/Radium alone
50+ y ago, cure rates for childhood cancers, Leukemia, Lymphoma skyrocketed with chemotherapy
40+ y ago, incurable germ cell tumors cured by platinum chemo
50+ y ago, cure rates for childhood cancers, Leukemia, Lymphoma skyrocketed with chemotherapy
40+ y ago, incurable germ cell tumors cured by platinum chemo
1/8
May 8th = World Ovarian Cancer Day 2022 #WOCD2022
A thread 🧵 on some points I wish to relay as a Medical Oncologist with subspecialty in GYN oncology and based in fair Ireland 🇮🇪
May 8th = World Ovarian Cancer Day 2022 #WOCD2022
A thread 🧵 on some points I wish to relay as a Medical Oncologist with subspecialty in GYN oncology and based in fair Ireland 🇮🇪
2/8
The most common symptoms of ovarian cancer are the #BEAT symptoms - always get checked out by your GP if you have these or other symptoms that are not resolving
#knowyourbody
The most common symptoms of ovarian cancer are the #BEAT symptoms - always get checked out by your GP if you have these or other symptoms that are not resolving
#knowyourbody
3/8
There is no reliable #screening test for ovarian cancer
❌ Pap smears do not diagnose ovarian cancer
❌ Ca125 is not a reliable test
❌ Pelvic/vaginal USS may miss a diagnosis or overdiagnose a normal cyst
Until we have better screening, symptoms are all we have #BEAT
There is no reliable #screening test for ovarian cancer
❌ Pap smears do not diagnose ovarian cancer
❌ Ca125 is not a reliable test
❌ Pelvic/vaginal USS may miss a diagnosis or overdiagnose a normal cyst
Until we have better screening, symptoms are all we have #BEAT
In a recent lung cancer pilot study, we identified and quantified a record number of 13,187 protein groups with our next-generation single-shot proteomics technology HRM.
This was achieved using FAIMS-DIA with highest resolution chromatography and FAIMS Exploris 480. (1/n)
This was achieved using FAIMS-DIA with highest resolution chromatography and FAIMS Exploris 480. (1/n)
The depth of analysis was superior to the one achieved in the Deep Human Proteome Atlas (deep fractionated tissue with multiple MS acquisitions, Wang et al., 2019, Mol Syst Biol).
Comprehensively, we could identify 414 oncogenes, 392 transcription factors, 837 plasma membrane proteins (25 GPCR), and 316 kinases covering a dynamic range of 10. In addition, 0.25 Mio peptides (including modifications) were measured in totality.
1/14 🆕 🚨Accelerated article on #breastcancer just out in @nature! #bcsm
We asked:
1️⃣ What drives response to #chemotherapy in #breast #cancer❓
2️⃣ Can we use #machinelearning to predict response to chemotherapy❓
Link: nature.com/articles/s4158…
A 🧵👇👇👇 @OncoAlert
We asked:
1️⃣ What drives response to #chemotherapy in #breast #cancer❓
2️⃣ Can we use #machinelearning to predict response to chemotherapy❓
Link: nature.com/articles/s4158…
A 🧵👇👇👇 @OncoAlert
2/14 We are unable to #predict #response to treatment in clinic…
✅Good response ➡️treatment very effective ➡️better survival
❌Poorer response ➡️treatment less effective ➡️worse survival
Being able to forecast response would be a landmark advance!
✅Good response ➡️treatment very effective ➡️better survival
❌Poorer response ➡️treatment less effective ➡️worse survival
Being able to forecast response would be a landmark advance!
3/14 We ran a study in women with #breastcancer @CUH_NHS+@CRUK_CI:
1️⃣who had a #cancer biopsy (which we analysed)
2️⃣received 18 weeks of chemo+/-targeted therapy
3️⃣had surgery (and we measured how much cancer remained)
We associated PRE-therapy profiles↔️POST-therapy response👇
1️⃣who had a #cancer biopsy (which we analysed)
2️⃣received 18 weeks of chemo+/-targeted therapy
3️⃣had surgery (and we measured how much cancer remained)
We associated PRE-therapy profiles↔️POST-therapy response👇
Critics of #TRIPSwaiver for #covid19 #vaccines stress importance of IPR protection for pharma industry and see future #innovation at risk. But the empirical evidence gives few indications of this. This thread explains why & proposes alternative innovation incentives.
Empirical evidence that increased patent protection leads to more innovation justifying its social costs is surprisingly thin: Little support in the literature that higher patent protection increases rate of innovation. Full references of citations: ÖFSE WorkingPaper linked below
Some studies even found statistically significant negative relationship between patent protection & productivity growth. Led to sharp increase in transaction costs&legal disputes -->discourages smaller firms&start-ups -->reduces technological innovation
1/2 Being a #virologist @DKFZ, I just HAVE to retweet this one. Yes, folks, #viruses do cause #cancer also in humans! Check out my #teaching slide in the next tweet! #HPV #HBV #HCV #EBV #HTLV #CancerResearch #infectiousdiseases #virology
@DKFZ 2/2 Merkel cell #carcinoma is a hideous #disease, but luckily very rare (though almost always associated w/ McPyV on the northern hemisphere). Even much, much more common #cancers are associated with #virus #infections (or #bacteria like H.pylori)! #HPV #HBV #HCV #EBV #HTLV
3/2 😅 Sorry, let me add one more remark: of course not ALL the shown #cancer cases are associated with #infections, but a significant fraction of the indicated cancer types are (e.g. #HPV in 99% of #CervicalCancer, aprx. 75% #HBV or #HCV in #livercancer!)
