Discover and read the best of Twitter Threads about #bullouspemphigoid
Most recents (1)
1/
BULLOUS PEMPHIGOID, a #dermatology #tweetorial!
#MedEd #FOAMEd #medtwitter #dermtwitter #medthread pc:@dermnetnz
A patient with active bullous #pemphigoid comes to see you. What do you expect on your exam?
BULLOUS PEMPHIGOID, a #dermatology #tweetorial!
#MedEd #FOAMEd #medtwitter #dermtwitter #medthread pc:@dermnetnz
A patient with active bullous #pemphigoid comes to see you. What do you expect on your exam?
2/
#bullouspemphigoid (BP) is an autoimmune blistering disorder where the pt's immune system makes auto-antibodies targeting BPAg 1&2 (BP230/BP180). Since these Ags are in the hemidesmosome, the split is lower in the skin, making for tense blisters.
pc: sciencedirect.com/science/articl…
#bullouspemphigoid (BP) is an autoimmune blistering disorder where the pt's immune system makes auto-antibodies targeting BPAg 1&2 (BP230/BP180). Since these Ags are in the hemidesmosome, the split is lower in the skin, making for tense blisters.
pc: sciencedirect.com/science/articl…
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Clinically, tense blisters (as seen in BP) usually go with a negative nikolsky, whereas flaccid blisters (seen in pemphigus) would have a positive nikolsky.
An easy mnemonic is:
pemphiguS = Superficial
pemphigoiD = Deep
Clinically, tense blisters (as seen in BP) usually go with a negative nikolsky, whereas flaccid blisters (seen in pemphigus) would have a positive nikolsky.
An easy mnemonic is:
pemphiguS = Superficial
pemphigoiD = Deep
