Discover and read the best of Twitter Threads about #Virological
Most recents (2)
TODAY at #Virological: throughout the #COVID19 pandemic, there has been a tendency to underestimate the potential of #SARSCoV2 to mutate and adapt.
As the @US_FDA meets Tuesday to discuss #molnupiravir, @sarperotto and I fear another oversight.🧵
1/15
virological.org/t/mutagenic-an…
As the @US_FDA meets Tuesday to discuss #molnupiravir, @sarperotto and I fear another oversight.🧵
1/15
virological.org/t/mutagenic-an…
To be clear, I believe vaccines and antiviral drugs BOTH have critical parts to play in the fight against #COVID19.
Oral antivirals are of particular interest given their potential for equitable distribution.
This is NOT an argument against antivirals.
2/15
Oral antivirals are of particular interest given their potential for equitable distribution.
This is NOT an argument against antivirals.
2/15
Antivirals can work via several mechanisms.
🦠PROTEASE INHIBITORS, like #paxlovid and #masitinib, prevent the production of mature viral proteins.
🧬MUTAGENS, like #molnupiravir, instead increase the viral mutation rate to intolerable levels, causing LETHAL MUTAGENESIS.
3/15
🦠PROTEASE INHIBITORS, like #paxlovid and #masitinib, prevent the production of mature viral proteins.
🧬MUTAGENS, like #molnupiravir, instead increase the viral mutation rate to intolerable levels, causing LETHAL MUTAGENESIS.
3/15
Dear @nytimes @cnn @vice @newsroomnz @thescientistllc @businessinsider @bbcnews @LaVanguardia @diariARA @NatureNews @sciencemagazine I suggest to every one of you to carefully and honestly think and reply to a very simple question regarding #bats #conservation #virus & #ethics. 
"A casual family wth 2 lovely children lives in the countryside, near a cave hosting thousands of bats. They never had an issue with them and don't know much about bats... but now they've read your most recent news and headings about #coronavirus. What would they immediately do?"
Let me give my personal view as a bat ecologist "They would probably seal the cave or massively kill as many bats as possible. Some could hopefully escape, but the colony wouldn't definitely be back." But don't misunderstand me. It is 100% logical, and I would have done the same.
