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1/As promised & after reading $CRSP latest Q4 2022 #financial #report here is my impression regarding @CRISPRTX latest corporate status. I have focused only on the main issues that I found to be the most interesting & relevant. #CRISPR #BioTech #FinTwit #Genomics #GeneEditing 🧵 
2/IMO the most significant corporate event in Q4 was $CRSP announcement that regulatory Exa-cel submissions of both #SickleCell & #BetaThalassemia validated in the #EU & #UK & that the @US_FDA BLA submission is on track by the end of Q1 ‘23 - possibly reaching the #markets in ‘23
3/Exa-cel/CTX001 - the key program in $CRSP portfolio, is an #autologous Ex-Vivo #CRISPR/#Cas9 #GeneEditing therapy aimed for patients suffering from #TDT or severe #SCD. The latest readout for both programs was phenomenal with 42/44 TDT & 31/31(!) demonstrated remarkable results
AB'nin Rus Gazı Mahrumiyeti ve Türklere Mecburiyeti
Bugün doğalgaz devi Rus #Gazprom şirketi,
Ursula von der Leyen'in başında bulunduğu AB heyetinin Bakü'de doğalgaz anlaşmasına imza attığı sırada Almanya'ya yaptığı doğalgaz akışını durdurması tesadüfi değil.👇
Bugün doğalgaz devi Rus #Gazprom şirketi,
Ursula von der Leyen'in başında bulunduğu AB heyetinin Bakü'de doğalgaz anlaşmasına imza attığı sırada Almanya'ya yaptığı doğalgaz akışını durdurması tesadüfi değil.👇
Avrupa'nın bugünlerde 'Güney gaz ve petrol koridorunun kilit ortağı' olarak nitelendirdiği #Azerbaycan, Rusya'nın doğalgaz üretim hacminde olmasa da Avrupa'daki sanayi çarklarının durmasını önleyebilecek en hızlı seçenek. Güney gaz koridoru ise doğrudan Türkiye'dir. 👇
#Ortadoğu gaz ve petrol tedarik ağının vazgeçilmez ülkesi Türkiye, en az maliyetle en güvenli gazı Avrupa'ya ulaştırması bakımından Batı için önemli bir ülkeydi. Artık sandığımızdan da önemli olmak üzere...👇
This is about Alpha Zero.
But I think it is basically how human impulse control works. If a person chronically makes "bad" short-term-oriented choices, it may very well be because they _correctly_ don't depend on themselves to be able to execute on a long term strategy.
But I think it is basically how human impulse control works. If a person chronically makes "bad" short-term-oriented choices, it may very well be because they _correctly_ don't depend on themselves to be able to execute on a long term strategy.
It's a lot less attractive to be "disciplined" and "responsible" and "prudent" if you're going to fuck it up somehow before you get the payoff.
You might as well seize some pleasure now, even if it is "self destructive" or reckless.
You might as well seize some pleasure now, even if it is "self destructive" or reckless.
If you're likely to fail anyway, there's less use in focusing on your studies. Might as well party.
If you're going to misinvest your savings, or break open the piggy bank to buy some random thing down the line, you might as well spend the money now.
If you're going to misinvest your savings, or break open the piggy bank to buy some random thing down the line, you might as well spend the money now.
