Discover and read the best of Twitter Threads about #SurrogateOutcomes
Most recents (1)
Last week I discussed composite endpoints and how while they can be useful, they can also be fraught with difficulty. The same descriptors could equally be applied to #SurrogateOutcomes in clinical trials 1/9
#MethodologyMonday
#MethodologyMonday
A #SurrogateOutcome is a substitute measure (eg blood pressure) that one might use to stand in for the real outcome of interest (eg stroke) when the real outcomes of interest may take a very long time to measure - to allow trials to be completed more quickly & efficiently 2/9
Surrogate outcomes can take many forms and may be histological, physiological, radiological etc … biomarkers that predict events 3/9
