Discover and read the best of Twitter Threads about #SINDAS
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#ASCO20 A lot to think about with the data from the #SINDAS trial: a randomized phase 3 trial of early local radiation therapy for patients with metastatic #EGFR mutant #NSCLC presented by Dr. Xiao-Shan Wang. #OncoAlert #LCSM 
#ASCO20 At this point, we're on board with the concept of oligometastatic NSCLC - that there is a spectrum within stage IV lung cancer and aggressive therapy for some will improve outcomes. Various definitions (would a biologic marker be better than # of radiographic lesions?)
#ASCO20 SINDAS enrolled 133pts with oligometastatic #EGFR NSCLC, defined as up to 5 metastases (max of 2 per organ), EXCLUDING brain metastases, ECOG 0-2. Used a 1:1 randomization to SBRT + TKI vs TKI alone, PFS primary endpoint. #OncoAlert #LCSM
