Discover and read the best of Twitter Threads about #PediatricHepatitis
Most recents (5)
1. #PediatricHepatitis: 2 groups of researchers in the UK have posted preprints that flesh out a new theory on what may be behind the apparent increase in cases of pediatric hepatitis of unknown etiology seen this spring in the UK & Europe & first reported in Alabama last fall.
2. The tl;dr version: It's complicated.
A combination of 3 factors, exacerbated by a 4th, is likely responsible for these cases of #PediatricHepatitis, the studies conclude. statnews.com/2022/07/25/new…
A combination of 3 factors, exacerbated by a 4th, is likely responsible for these cases of #PediatricHepatitis, the studies conclude. statnews.com/2022/07/25/new…
3. For a time, the leading theory was that these unusual cases of #PediatricHepatitis were caused by adenovirus 41, which was found in all the Alabama cases & a number in the UK. But the new theory suggests it's more complicated than that.
1. A thread on #PediatricHepatitis of unknown etiology.
@WHO issued an update today. It reports that 35 countries have reported 1010 cases. There've been 22 deaths (2%) & 46 (5%) of the children have needed liver transplants.
@WHO issued an update today. It reports that 35 countries have reported 1010 cases. There've been 22 deaths (2%) & 46 (5%) of the children have needed liver transplants.
2. @WHO says it appears that the trend of cases is decreasing, but notes this should be interpreted with caution because there are reporting delays, likely under-reporting, and limited surveillance for such cases in many countries.
3. To that end, @WHO has launched an effort to try to assess whether there is a true increase in #PediatricHepatitis cases in the past 10 months or so. This comes on the heels of data from @CDCgov showing there has not been an increase of liver transplants among kids in the US.
1. Short 🧵 on #PediatricHepatitis of unknown origin in kids.
@ECDC_EU & @WHO_Europe put out an update today on cases in Europe.
There've been 402 cases in 20 countries. 87 of those children have needed ICU care & 17 got liver transplants. ecdc.europa.eu/en/hepatitis/j…
@ECDC_EU & @WHO_Europe put out an update today on cases in Europe.
There've been 402 cases in 20 countries. 87 of those children have needed ICU care & 17 got liver transplants. ecdc.europa.eu/en/hepatitis/j…
2. Last week @WHO said it had been notified of 700 cases of #PediatricHepatitis globally & at least 10 deaths.
In Europe, 1 child has died. 78% of the children are under the age of 5.
In Europe, 1 child has died. 78% of the children are under the age of 5.
3. The @ECDC_EU / @WHO_Europe update on #PediatricHepatitis has an epicurve that shows either date of onset of illness or hospitalization, depending on what info is available. It urges caution in trying to interpret what looks like a recent decline in new cases.
HEPATITIS AGUDA INFANTIL de origen desconocido
¿Realmente la está causando el #Adenovirus F41? 🧐
Hay algunos puntos a considerar. Va mi opinión al respecto🧵👇🏼
1/15
#HepatitisAgudaInfantil
¿Realmente la está causando el #Adenovirus F41? 🧐
Hay algunos puntos a considerar. Va mi opinión al respecto🧵👇🏼
1/15
#HepatitisAgudaInfantil
Hace un mes (15Abr22) nos enteramos de que Reino Unido 🇬🇧 estaba reportando un incremento inusual en los casos de #hepatitis de origen desconocido en pacientes pediátricos, especialmente en l@s más jóvenes
Después otros países empezaron a reportar lo mismo (tot: 169 casos)
2/15
Después otros países empezaron a reportar lo mismo (tot: 169 casos)
2/15
La presentación clínica, es decir, la manera en la que el personal médico identifica la enfermedad👩🏻⚕️, es una #HepatitisAguda (el surgimiento rápido de inflamación en el hígado) con una elevación muy pronunciada 📈 en los niveles de proteínas provenientes de ese órgano¹
3/15
3/15
1. Interesting update on #PediatricHepatitis from @ECDC_EU + @WHO_Europe. It contains the first epicurve I've seen, which is very helpful because reported cases include current & previous cases found through record searches. The 1st case here dates to Sept 2021.
2. A large majority of the European #PediatricHepatitis cases are really young — 76% under the age of 5.
3. The @ECDC_EU/@WHO_Europe #PediatricHepatitis update says as of May 13, a total of 232 cases have been reported. Puzzled by the UK number (131) because yesterday @UKHSA reported 176 cases.
This report reports 3 epidemiologically linked cases, which is interesting.
This report reports 3 epidemiologically linked cases, which is interesting.
