Discover and read the best of Twitter Threads about #PIMSTS

Most recents (10)

Great work @acemonline SA team including @AWalterPerry organising tonight’s #COVID19 update with updates from Sydney, Melbourne & Adelaide Image
Tips from Dr Andrew Cooke, St George:
* Tolerate uncertainty - lesson 1
* an iterative approach to determining hot/cold zones, PPE etc
* workshopped training to build muscle memory
* accessible, continually updated guidelines via internal website ImageImage
* getting used to proning; which patients qualify for HFNO
* Covid shuttle bus helped with ED flow for discharges from the ward/ED
* grief & disbelief when family members not allowed to visit
* stigma of being #COVID19 (+) delaying seeking care
* a lot of anxiety in patients ImageImage
Read 30 tweets
1/
#PedsICU conversations
Just out our paper in @PedCritCareMed led by the fabulous @AnnaZanin_MD 🇮🇹 on the Live Tweeting the Discovery of #COVID19 related Syndrome in Children (#PIMS #MISC)

Nuestro artículo sobre descubrimiento Sínd niños y @Twitter

journals.lww.com/pccmjournal/Ci…
2/
Doctors have discussed clinical cases since its inception, COnversations among peers and sharing is key for medicine knowledge advancements

Los médicos siempre conversaron entre ellos y así la medicina avanza

(Rembrandt) #historicmedtwitter
smarthistory.org/rembrandt-anat… Image
3/
These conversations abled naming of diseases, etc. Unfortunately, many of those inventions/discoveries remained in silos, and massive global dissemination was impossible in real time. Moreover, tracking the origins and giving merits was difficult.
Read 19 tweets
Here is the #PedsICU #BestOf2020 collection.
Jointly chosen by
@Dr_Hari_Krishna @sgdambrauskas and myself
Pubmed collection 40 articles: bit.ly/pedsicubestof2…
Infographic (clickable PDF) in English: bit.ly/bestof2020eng
Spanish: bit.ly/bestof2020esp
#PedsCICU #NeuroPICU
This will be a bilingual tweetorial in Spanish/English!
Infographics are available in both languages in Tweet #1

El hilo será en Español/Inglés. El resumen infográfico está disponible en los dos idiomas en el primer Tweet
1/What are the outcomes that matter to children, to families and to #researchers/clinicians? @ericka_fink et al & @PostPICU_PALISI investigators identified COS using a delphi process. @CritCareMed bit.ly/381cfq8. Developmental and functional outcomes were important.
Read 44 tweets
#Tweetorial
Llegó colección de lo #Mejor2020 en #PedsICU &
@Dr_Hari_Krishna 🇬🇧@MiguelrrMD 🇪🇸 @sgdambrauskas 🇺🇾

Pubmed: bit.ly/pedsicubestof2…
Versión infográfico español: bit.ly/bestof2020esp
Version inglés: bit.ly/bestof2020eng

#SoMe4MV #neuroPICU #delirium #PedsCICU
English #BestOf2020
The #Bestof2020 #PedsICU pubmed collection will also be available in the FREE #PICCHub app (sponsored by @PICSociety) as the latest monthly #PICUJournalwatch collection:
Download links: Android: play.google.com/store/apps/det…
iOS: apps.apple.com/gb/app/picchub…
3/ La FUNCIÓN como nuevo paradigma
@ericka_fink et al POST #PedsICU investigators & @PALISInet hicieron consenso Delphi
Qué es lo importante como resultados al alta #PedsICU?

En @CritCareMed lo que encontraron con precioso infogràfico
bit.ly/381cfq8
#PedsICU #PICSp
Read 42 tweets
2020 has been extraordinary.

But we wanted to share the 10 reasons we are proud of 2020 by the S-Lab research group of @PICU_BCH & @BacrUob @unibirmingham

AND to say a HUGE 'thank you' to everyone who has made this possible #teamscience #PedsICU #2020
1)In the last 12 months we have built up a team of Neuro-critical care, resuscitation science, early rehabilitation and COVID19/PIMS-TS researchers for in Birmingham to improve the lives of critically unwell children. Currently called the S(cholefield)-Lab pending a better name!
2)In 2020 we watched our early career researchers shine

Hussin Albargi @AlBaRqi14 (PhD student: paediatric prehospital cardiac arrest)
Mirjam Kool @mirjam_kool (ACF – post-arrest #TTM Intra-arrest physiological monitoring @ILCOR) & 1st publication! tinyurl.com/ybk854tb
Read 24 tweets
Next is Prof Elizabeth Draper discussing the data reported and modelling from the UK on #COVID19 data in #PedsICU

#EPCCS20
Roles included:
* modelling #PedsICU bed requirement in the #COVID19 pandemic to ensure enough #PICU beds
* report real time #COVID cases & #PIMSTS in kids

This is helpful data for us to learn and adapt to this disease

#EPCCS20
The number of children admitted to #PedsICU with #COVID19 followed the same wave as adults, but obviously lower numbers. Starting to slowly increase again....

#EPCCS20
Read 4 tweets
Prof Mike Levin talking to us about the #physiology and #immunology of #COVID19 and #PIMSTS in #PedsICU

Generally children had a mild disease phenotype - then as the pandemic progressed more inflammatory disorders were seen and a new condition was created: PIMS-TS

#EPCCS20
Further investigation of the #COVID19 inflammatory response found 3 phenotypes - all had coronary artery disease, but not all needed #PedsICU

#EPCCS20
The new disease when compared to Kawasaki disease:
- higher CRP
- younger age
- higher ferritin
- lower lympocytes
- lower albumin
- lower haemoglobin

Shock patients:
- higher troponin
- higher BNP
- higher CRP

#PedsICU #COVID19 #EPCCS20
Read 7 tweets
Cool study in @CDCMMWR about #MISC #PIMSTS in the US

cdc.gov/mmwr/volumes/6…

Taking 570 reported cases (med age 8y, 40% hispanic/latino, 33% black) they performed statistical analysis to break cases down into 3 categories

1/7
Using a method called latent class analysis (a supervised technique maximising differences between classes and minimising differences within classes) they created 3 gruops - the breakdown is interesting so lets take a look!

2/7
Group 1: "Classic" MISC/PIMSTS which is features of muti-organ involvement and shock with only 1/3 patients testing positive on rtPCR

Group 2: High respiratory involvement and vast majority testing positive for SARS-CoV-2 rt PCR

3/7
Read 8 tweets
No10 has told Scotland no more furlough payments unless they follow No10 on lifting lockdown restrictions

Sadiq Khan has been forced by No10 to raise fairs and the Congestion Charge in return for bailing out TFL

No10 will force councils to open schools in return for bailouts
Its up to us to not send our kids to school & place direct pressure on our councils not to cave it to Tory pressure

Its not safe for our kids yet, the Tories know this, are lying saying it is, they don't care if your child dies

Likes of Eton are not reopening until September
Keep an eye on the #PIMSTS hash tag

Doctors are finding that some children who have had Covid19 are getting a Kawasaki like disease a few weeks later, they have called PIMS-TS

manchestereveningnews.co.uk/news/uk-news/i…
Read 9 tweets
Thanks to @cdc we’re now calling it MIS-C. #MISC (can’t have hyphens in hashtags).
MIS-C Tweetorial: Here’s recent alert from CDC regarding this multisystem inflammatory syndrome in children (MIS-C, or #PIMSTS on #medtwitter). emergency.cdc.gov/han/2020/han00…. This Kawasaki-like syndrome was noted about 4 weeks after #COVID peak in Italy #PedsICU
CDC named it MIS-C, diagnosed by:
✅T>38 for 24hrs
✅⬆️CRP, ESR, ferritin, procal, or IL-6, etc
✅>=2 organ system dysfxn
✅no other infxn/reason for sxs
✅recent #COVID19 or just exposure (many are PCR-, variable serology)
Read 14 tweets

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