Discover and read the best of Twitter Threads about #Ibuprofen
Most recents (9)
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses.
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses.
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic.
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic.
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus.
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus.
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component.
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component.
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%.
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%.
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies.
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies.
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others
Indeed, I got #COVID19 🤒My symptoms were high fever, short breadth, cough, and tiredness. Luckily it was not too bad, I have no other conditions, so I healed at home in 2 weeks. I am completely fine now, so don't worry!😊These things, above all, helped with my healing:
(1 ~ 5)
(1 ~ 5)
(2~ 5)1⃣#Paracetamol kept my fever under control. I avoided #Ibuprofen as a matter of precaution as there were some concerns spreading. Not sure they were scientifically supported, but Paracetamol was good enough for me so I sticked to that,
For those following the confusion around #ibuprofen: @ScienceMagazine just published a letter. It’s a bit technical, but bottom line: "People taking NSAIDs for other reasons should not stop doing so for fear of increasing their #COVID19 risk.” h/t @hholdenthorp
@ScienceMagazine @hholdenthorp So: "until we have robust evidence, patients in chronic pain should continue to take their NSAIDs rather than turn to opiates.”
And: "Patients on ACE inhibitors should continue to take them rather than risk complications, such as stroke.”
science.sciencemag.org/content/early/…
And: "Patients on ACE inhibitors should continue to take them rather than risk complications, such as stroke.”
science.sciencemag.org/content/early/…
@ScienceMagazine @hholdenthorp This is also @WHO advice. Spokesperson told me today: “At present, based on currently available information, WHO does not recommend against the use of ibuprofen.” So everyone take a deep breath and keep taking your meds. Update if and when anything changes.
1. @WHO @TheLancet My thought about #Ibuprofen is its tendency to thin blood. Imagine an 80 year old coughing hard for two weeks. Like going a round of boxing. Internal bleeds add up and thinner makes it unstoppable. Would you recommend it pre-op? I don't think so.
2. It's not the noninflammatory NSAID mechanism. Just the bleeding side-effect that triggers all the d-dimer elevations. Look at the charts if they had work up at admission. Ask family. I think aspirin or heparin would be the same. Maybe a lot worse. @cnn @MSNBC @DefenseIntel
3. We home hospiced my 94 year-old mother. Their blood vessels are frail. #NotADoctor Just son who observed someone die of old age.
1. My update on the comment Italy has young people becoming very ill. It's my understanding #Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using ibuprofen, especially in older adults.
2. The mortality data recently shows the presence of the d-dimer protein that is tested in cases of #DVT #bloodclots. The people who die show it elevated. Ones who survive don't. I think @CDCemergency @MassGeneralNews and other researchers need to determine if the organ failures
3. are being caused or exacerbated by blood thinning medications that may, in cases of of treating #COVID19 be taken by the public self-medicating over-the-counter #Ibuprofen as part of a treatment course. If there has been any more data feel free to post. @TheLancet @CDCgov
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Ich bin kein Virologe, möchte aber gern die Hypothese analysieren / widerlegen, dass #Ibuprofen eine #Coronavirusinfektion verschlimmern kann.
Am 29. Januar wurde bereits in einer virologischen Fachzeitschrift (DOI: 10.1128/JVI.00127-20) der Mechanismus des #Coronavirus ...
Ich bin kein Virologe, möchte aber gern die Hypothese analysieren / widerlegen, dass #Ibuprofen eine #Coronavirusinfektion verschlimmern kann.
Am 29. Januar wurde bereits in einer virologischen Fachzeitschrift (DOI: 10.1128/JVI.00127-20) der Mechanismus des #Coronavirus ...
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analysiert, wie dieser mit der menschlichen Wirtszelle interagiert. Dabei bindet ein Eiweiß des Virus (Spike (S)-Protein) an eine Bindungsstellen eines humanen Eiweiß (Angiotensin-Converting-Enzym-2 = ACE2) und somit kann das Virus über molekulare Veränderungen in die ...
analysiert, wie dieser mit der menschlichen Wirtszelle interagiert. Dabei bindet ein Eiweiß des Virus (Spike (S)-Protein) an eine Bindungsstellen eines humanen Eiweiß (Angiotensin-Converting-Enzym-2 = ACE2) und somit kann das Virus über molekulare Veränderungen in die ...
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Zielzelle gelangen und sich dort vermehren.
Im Lancet (medizinische Fachzeitschrift) wurde am 11.03. ein Artikel (doi.org/10.1016/S2213-…) veröffentlich, wo NUR EINE HYPOTHESE beschrieben wird. Dort wird SPEKULIERT, dass Patienten mit Diabetes und Bluthochdruck, die mit ...
Zielzelle gelangen und sich dort vermehren.
Im Lancet (medizinische Fachzeitschrift) wurde am 11.03. ein Artikel (doi.org/10.1016/S2213-…) veröffentlich, wo NUR EINE HYPOTHESE beschrieben wird. Dort wird SPEKULIERT, dass Patienten mit Diabetes und Bluthochdruck, die mit ...
IOL Chemical CMP 255
✍️ Ibuprofen price increased from $15 to $18. Management expects it to touch $20
✍️ Recently, Dept. of pharmaceuticals has clarified that no ban has been proposed on export of APIs & formulations in the wake of coronavirus outbreak
✍️ Ibuprofen price increased from $15 to $18. Management expects it to touch $20
✍️ Recently, Dept. of pharmaceuticals has clarified that no ban has been proposed on export of APIs & formulations in the wake of coronavirus outbreak
✍️ IOLCP is having 30% World Mkt Share of Ibuprofen
✍️ 1 Ibuprofen manufacturer which has 15% world Mkt Share is in Hubei province & it is in complete shutdown due to coronavirus outbreak
✍️ Ibuprofen demand increased due to Supply Constraint
✍️ Co. is having 6 months Inventory
✍️ 1 Ibuprofen manufacturer which has 15% world Mkt Share is in Hubei province & it is in complete shutdown due to coronavirus outbreak
✍️ Ibuprofen demand increased due to Supply Constraint
✍️ Co. is having 6 months Inventory
✍️ IOLCP is a leader in India for #Ibuprofen.
✍️ Two cos in India which manufacture Ibuprofen (#IOLCP & #Solara)
✍️ Co is not increasing Ibuprofen prices in Indian Mkt
✍️ Co has already started getting Ibuprofen orders at $18
✍️ Currently Ibuprofen capacity utilization is 80%
✍️ Two cos in India which manufacture Ibuprofen (#IOLCP & #Solara)
✍️ Co is not increasing Ibuprofen prices in Indian Mkt
✍️ Co has already started getting Ibuprofen orders at $18
✍️ Currently Ibuprofen capacity utilization is 80%
