Discover and read the best of Twitter Threads about #Gryphon
Most recents (6)
BREAKING🔔 The 21st paper from G2P-Japan🇯🇵 is out at Nature Communications @NatureComms . We illuminated the virological characteristics of SARS-CoV-2 XBB variant (aka #Gryphon), generated by the recombination of two #Omicron subvariants. Please RT! 1/
nature.com/articles/s4146…
nature.com/articles/s4146…
In late 2022, the Omicron subvariants have highly diversified. An example is BQ.1.1, which have convergently acquired amino acid substitutions at five critical residues in the spike protein: R346T, K444T, L452R, N460K & F486V. We reported it as below⬇️ 2/
Another variant of concern is XBB. First, two young talents, @jampei2 & @SpyrosLytras, showed that XBB emerged by recombination of two co-circulating BA.2 lineages, BJ.1 & BM.1.1.1 (a progeny of BA.2.75), during summer 2022. 3/ 
BREAKING🔔 The 15th preprint from G2P-Japan🇯🇵 is out @biorxivpreprint. We illuminated the virological characteristics of one of the latest SARS-CoV-2 lineages of concern, XBB, which was generated by recombination of two #Omicron subvariants. Please RT. 1/
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…
In late 2022, the Omicron subvariants have highly diversified. An example is BQ.1.1, which has convergently acquired amino acid substitutions at five critical residues in the spike protein: R346T, K444T, L452R, N460K & F486V. We reported it as below⬇️ 2/
Another variant of concern is XBB (aka #gryphon). First, two young talents, @jampei2 & @SpyrosLytras, showed that XBB emerged by recombination of two co-circulating BA.2 lineages, BJ.1 & BM.1.1.1 (a progeny of BA.2.75), during 2022 summer in India or its neighboring countries. 3/
#SARSCoV2 #Variants are collecting identical sets of concerning mutations (aka #Convergent #Evolution)
Latest threat is from the recombinant lineage #XBB (BJ.1/BM.1.1.1), the most immune-evasive #COVID strain seen yet
H/T @ErinMPrater @FortuneMagazine
Latest threat is from the recombinant lineage #XBB (BJ.1/BM.1.1.1), the most immune-evasive #COVID strain seen yet
H/T @ErinMPrater @FortuneMagazine
XBB (aka #Gryphon) is the most immune evasive lineage.
BA.2.75* sub-lineages bind better to host ACE2 receptor.
XBB could pick up addition mutations to optimize its ACE receptor binding!
BA.2.75* sub-lineages bind better to host ACE2 receptor.
XBB could pick up addition mutations to optimize its ACE receptor binding!
Tracking #SARSCoV2 #Convergent #Lineages ( aka #VariantSoup) over time - Globally | #30DayTrends
BQ.1 (#Typhon)/BQ.1.1(#Cerberus) are currently at the top & BA.2.75.2* (#Chiron) is not far behind!
Tracker: public.tableau.com/app/profile/ra…
Updated 10/7/2022
BQ.1 (#Typhon)/BQ.1.1(#Cerberus) are currently at the top & BA.2.75.2* (#Chiron) is not far behind!
Tracker: public.tableau.com/app/profile/ra…
Updated 10/7/2022
Granular details - #VariantSoup with Convergent Mutations #30DayTrends
BQ.1/BQ.1.1 and BA.2.75.2 are heading the charts!
2/n
BQ.1/BQ.1.1 and BA.2.75.2 are heading the charts!
2/n
Tracked #Convergent #lineages are predicted to be immune evasive and bind to host ACE2 receptor better than Omicron.BA2
XBB is most immune evasive
Most BA.2.75* binds better to ACE2 receptors
Closely watched lineages - XBB, BM.1.1.1, CA.1, BQ.1.1, BN.1
3/n
XBB is most immune evasive
Most BA.2.75* binds better to ACE2 receptors
Closely watched lineages - XBB, BM.1.1.1, CA.1, BQ.1.1, BN.1
3/n
#COVID19 #VariantDashboard - #UnitedStates
TOP lineages (15-DAY TRENDS):
21.4% BA.5.2.1
13.6% BA.5.2
10.9% BA.4.6
9.9% BA.5.1
3.9% BF.10
3.5% BA.5.5
3.0% BA.5.6
2.2% BF.7
2.2% BA.5.2.9
1.8% BA.5
Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 10/03/22
1/n
TOP lineages (15-DAY TRENDS):
21.4% BA.5.2.1
13.6% BA.5.2
10.9% BA.4.6
9.9% BA.5.1
3.9% BF.10
3.5% BA.5.5
3.0% BA.5.6
2.2% BF.7
2.2% BA.5.2.9
1.8% BA.5
Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 10/03/22
1/n
Top circulating lineages (#15DayTrends)
81.7% BA.5*
10.9% BA.4.6*
2.2% BF.7*
1.5% BA.2.75*
1.4% BA.4*
1.4% BQ.1*
0.5% BQ.1.1*
0.2% BA.2.3.30*
0.02% XBB*
2/n
81.7% BA.5*
10.9% BA.4.6*
2.2% BF.7*
1.5% BA.2.75*
1.4% BA.4*
1.4% BQ.1*
0.5% BQ.1.1*
0.2% BA.2.3.30*
0.02% XBB*
2/n
#COVID19 #VariantDashboard - #UnitedStates
TOP lineages (15-DAY TRENDS):
23.2% BA.5.2.1
13.5% BA.5.2
10.6% BA.5.1
10.0% BA.4.6
4.0% BF.10
3.3% BA.5.5
2.8% BA.5.6
2.4% BA.5.2.9
2.2% BF.7
2.0% BA.5
Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 10/02/22
1/n
TOP lineages (15-DAY TRENDS):
23.2% BA.5.2.1
13.5% BA.5.2
10.6% BA.5.1
10.0% BA.4.6
4.0% BF.10
3.3% BA.5.5
2.8% BA.5.6
2.4% BA.5.2.9
2.2% BF.7
2.0% BA.5
Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 10/02/22
1/n
Top circulating lineages (#15DayTrends)
83.7%BA.5*
10% BA.4.6*
2.2%BF.7*
1.5%BA.4*
1.2%BA.2.75*
0.5%BQ.1*
0.3%BA.2.3.30*
0.4%BQ.1.1*
2/n
83.7%BA.5*
10% BA.4.6*
2.2%BF.7*
1.5%BA.4*
1.2%BA.2.75*
0.5%BQ.1*
0.3%BA.2.3.30*
0.4%BQ.1.1*
2/n
