Discover and read the best of Twitter Threads about #FalseNegative
Most recents (4)
Joseph Burrascano, MD - Diagnostic Tools
#Lyme Clinical Presentation: nonspecific, viral-like symptoms that persist, & new ones appear. Then symptoms more focused on musculoskeletal, peripheral and central nervous systems, heart and skin. Muti-systemic & migratory. #ILADS2022
#Lyme Clinical Presentation: nonspecific, viral-like symptoms that persist, & new ones appear. Then symptoms more focused on musculoskeletal, peripheral and central nervous systems, heart and skin. Muti-systemic & migratory. #ILADS2022
2/Burrascano: Sorting out the co-infections #NotJustLyme #Bartonella #Babesia #Ehrlichia #Anaplasma #Mycoplasma #ILADS2022
3/Burrascano: Types of tests
SEROLOGIES are indirect, B-cell based tests:
B-cells create antibodies and serologies measure these antibodies #ILADS2022
SEROLOGIES are indirect, B-cell based tests:
B-cells create antibodies and serologies measure these antibodies #ILADS2022
What is the epidemiological impact of a #falsenegative #COVID test? An important question in a high vaxx/low NPI context, but one that cannot be studied in a experiment for obvious reasons. Enter the UK, a reliable supplier of #naturalexperiments. 🧵⬇️
➡️bit.ly/3DhqQv5
➡️bit.ly/3DhqQv5
On Oct 15, @UKHSA suspended an #Immensa lab, because of community reports of neg PCR tests following a pos lateral flow. There was loads of excellent reporting e.g. by @rowenamason @tomjs @JamieGrierson. NHS TT estimates that 43,000 individuals may have been given a .. 2/N
false negative result most concentrated in South West of England. Even across all of England, a notable increase in both absolute # and relative % of PCR tests matched to a positive LFD tests producing a negative result from early Sept to early Oct 3/N
So not so much a #ContactTracing app as a feature-creeping Christmas tree?
One thing about tech that's successful is that it is ultimately successful because it performs the core function it (cl)aims to provide well.
#efficacious ≠ #effectiveness
One thing about tech that's successful is that it is ultimately successful because it performs the core function it (cl)aims to provide well.
#efficacious ≠ #effectiveness
In case you're wondering, "Detection rate" refers to detecting other #phones with the app installed, not the #virus:
The #FalseNegative rate is the amount of times the app incorrectly reports a contact as 'non-infectious' when in fact it is / could be...
The #FalseNegative rate is the amount of times the app incorrectly reports a contact as 'non-infectious' when in fact it is / could be...
...and the #FalsePositive rate is how often the app incorrectly reports a contact as 'infectious' when it's not, i.e. a #FalseAlarm.
Basically, what these #ErrorRates tell us is that #Bluetooth ranging is HARD!
Would you trust a #SmokeAlarm that went off wrongly nearly half...
Basically, what these #ErrorRates tell us is that #Bluetooth ranging is HARD!
Would you trust a #SmokeAlarm that went off wrongly nearly half...
1/ Q: I want to visit older family members soon, so I went and got a #PCR test for #COVID__19 (i.e., the kind that detects *current* infection). My test came back negative, so I am in the clear, right?
A: Not necessarily. It is possible you got a false negative test result.
A: Not necessarily. It is possible you got a false negative test result.
2/ After you are exposed to #SARSCoV2, the amount of #virus in your body builds up over time. It reaches its highest level right before symptom onset.
It can take 2-14 days (average of 5-6) from the time of exposure to when symptoms develop: a.k.a. the incubation period.
It can take 2-14 days (average of 5-6) from the time of exposure to when symptoms develop: a.k.a. the incubation period.
3/ Based on this incubation period, and because it is ideal to identify cases before they even develop symptoms, #publichealth experts currently recommend people get tested about 4 days AFTER a suspected exposure.
