Discover and read the best of Twitter Threads about #FactorialTrial

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The #FactorialTrial design is one of the very original efficient trial designs yet its potential often remains underused 1/7
#MethodologyMonday
In a #FactorialTrial you can evaluate the effectiveness of more than one treatment simultaneously and for the same sample size requirements as doing a single trial 2/7
bmcmedresmethodol.biomedcentral.com/articles/10.11…
For a factorial trial of say 2 treatments, patients are allocated to 1 of 4 groups: Gp1 receives both treatments A and B; Gp2 receives only A; Gp3 receives only B; and Gp4 receives neither A nor B (the control) 3/7
cambridge.org/core/services/…
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